Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Elias A, Lianos"'
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3297 (2023)
Overexpression of the inducible heme oxygenase (HO-1) isoform in visceral renal glomerular epithelial cells (podocytes) using in vivo transgenesis methods was shown to increase glomerular expression of the complement regulatory protein decay-accelera
Externí odkaz:
https://doaj.org/article/2027aabf76a84519955ccacdd87f2337
Autor:
Maria G. Detsika, Elias A. Lianos
Publikováno v:
Current Issues in Molecular Biology, Vol 43, Iss 2, Pp 1081-1089 (2021)
In systemic hemolysis and in hematuric forms of kidney injury, the major heme scavenging protein, hemopexin (HPX), becomes depleted, and the glomerular microvasculature (glomeruli) is exposed to high concentrations of unbound heme, which, in addition
Externí odkaz:
https://doaj.org/article/e66f2a3524c54792b28799721ee843cc
Autor:
Elias A. Lianos, Maria G. Detsika
Publikováno v:
Antioxidants, Vol 12, Iss 7, p 1322 (2023)
Heme oxygenase (HO)-1 is a well-known cytoprotective enzyme due to its enzymatic action, which involves the catalysis of heme into anti-apoptotic and antioxidant molecules such as bilirubin, biliverdin and CO [...]
Externí odkaz:
https://doaj.org/article/5dcda523196a4eafaa56fe68c59fa477
Publikováno v:
Antioxidants, Vol 12, Iss 1, p 61 (2022)
Heme oxygenase has been implicated in the regulation of various immune responses including complement activation. Using a transgenic rat model of HO-1 depletion, the present study assessed the effect of HO-1 absence on the expression of complement re
Externí odkaz:
https://doaj.org/article/6a83fba6cb704563b054d1100a0db897
Publikováno v:
Data in Brief, Vol 22, Iss , Pp 279-285 (2019)
The data presented pertain to a research article titled ''Heme Oxygenase 1 Up-Regulates Glomerular Decay Accelerating Factor Expression and Minimizes Complement Deposition and Injury'' (Detsika et al., 2016). The present work provides additional data
Externí odkaz:
https://doaj.org/article/df03f4cae7ec4f63b448ff3b35fcb295
Autor:
Maria G. Detsika, Eleni D. Myrtsi, Sofia D. Koulocheri, Serkos A. Haroutounian, Elias A. Lianos, Charis Roussos
Publikováno v:
Biochemistry and Biophysics Reports, Vol 19, Iss , Pp - (2019)
The involvement of complement activation in various forms of cardiovascular disease renders it an important factor for disease progression and therapeutic intervention. The protective effect of resveratrol against cardiovascular disease via moderate
Externí odkaz:
https://doaj.org/article/47f6fb43a2394b06a040b578c0d2691a
Autor:
Maria G. Detsika, Elias A. Lianos
Publikováno v:
Antioxidants, Vol 10, Iss 1, p 60 (2021)
Heme oxygenase is a cytoprotective enzyme with strong antioxidant and anti-apoptotic properties. Its cytoprotective role is mainly attributed to its enzymatic activity, which involves the degradation of heme to biliverdin with simultaneous release of
Externí odkaz:
https://doaj.org/article/a60ba489d4914386867e56fc5899f6e5
Publikováno v:
Data in Brief, Vol 5, Iss C, Pp 921-925 (2015)
This article reports data describing HO-1 expression patterns of heme oxygenase (HO)-1 in isolated rat glomeruli and in cultured glomerular epithelial cells (GEC) in response to its natural substrate heme. Qualitative and quantitative data are presen
Externí odkaz:
https://doaj.org/article/ac1f2e2316394bb0920cc89b94793835
Autor:
Maria G. Detsika, Elias A. Lianos
Publikováno v:
Current Issues in Molecular Biology
Volume 43
Issue 2
Pages 77-1089
Current Issues in Molecular Biology, Vol 43, Iss 77, Pp 1081-1089 (2021)
Volume 43
Issue 2
Pages 77-1089
Current Issues in Molecular Biology, Vol 43, Iss 77, Pp 1081-1089 (2021)
In systemic hemolysis and in hematuric forms of kidney injury, the major heme scavenging protein, hemopexin (HPX), becomes depleted, and the glomerular microvasculature (glomeruli) is exposed to high concentrations of unbound heme, which, in addition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b878d5133e835d286366076a08109298
https://doi.org/10.3390/cimb43020077
https://doi.org/10.3390/cimb43020077
Autor:
Hariklia Gakiopoulou, K. Goudevenou, Maria G. Detsika, Elias A. Lianos, Aron M. Geurts, Eirini Grapsa
Publikováno v:
Transgenic Research. 30:11-21
Decay accelerating factor (DAF), a key complement activation control protein, is a 70 kDa membrane bound glycoprotein which controls extent of formation of the C3 and C5 convertases by accelerating their decay. Using clustered regularly-interspaced s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2accb084c1468070e21bbbf83d0c849d
https://doi.org/10.1007/s11248-020-00222-x
https://doi.org/10.1007/s11248-020-00222-x