Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Elias, Adikwu"'
Publikováno v:
Pharmaceutical and Biomedical Research, Vol 9, Iss 1, Pp 7-16 (2023)
Background: Oxidative stress may be a causative factor for bisphenol A (BPA) -induced hepatotoxicity. Glutamine (GM) is an amino acid with the ability to inhibit oxidative stress. Objective: This study evaluated the ability of GM to prevent BPA-induc
Externí odkaz:
https://doaj.org/article/be6c4c82ef8441acbd3c41c81296643e
Publikováno v:
Journal of Clinical and Basic Research, Vol 6, Iss 3, Pp 23-26 (2022)
Background and objectives: Bisphenol A (BPA) can impair kidney function via oxidative stress. Glutamine (Gln) is an amino acid with antioxidant and immunomodulatory activities. This study assessed the protective activity of Gln against BPA-induced ne
Externí odkaz:
https://doaj.org/article/0103311889cb401282d61138b0475a09
Publikováno v:
Journal of Research in Applied and Basic Medical Sciences, Vol 8, Iss 4, Pp 189-195 (2022)
Background & Aims: Human immunodeficiency virus (HIV) is a retrovirus belonging to the family of lentiviruses. It is the causative organism of Acquired Immune Deficiency Syndrome (AIDS), which has become one of the greatest public health challenges f
Externí odkaz:
https://doaj.org/article/25cfb345874e42fc8d71067c0ebdafde
Autor:
Udeme Owunari Georgewill, Elias Adikwu
Publikováno v:
Biology, Medicine & Natural Product Chemistry, Vol 11, Iss 1, Pp 1-6 (2022)
Antimalarial drug resistance is one of the greatest challenges towards eradicating malaria. Exploring new combination therapies can overcome resistance challenges. The present study examined the antiplasmodial effect of artemether/lumefantrine/doxycy
Externí odkaz:
https://doaj.org/article/adeb8c1dafb1471cb9cade1fc064e11d
Publikováno v:
Journal of Human Reproductive Sciences, Vol 15, Iss 4, Pp 337-342 (2022)
Background: The induction of testicular toxicity by bisphenol A (BPA) may involve oxidative stress. Glutamine (Gln) is a rate limiter for the synthesis of glutathione (GSH), which inhibits oxidative stress. Aim: This study assessed the potential of B
Externí odkaz:
https://doaj.org/article/386b1b67b01f444a8ee608bae9647c9d
Autor:
Udeme Owunari Georgewill, Elias Adikwu
Publikováno v:
Biology, Medicine & Natural Product Chemistry, Vol 10, Iss 2, Pp 135-140 (2021)
Artemisinin-based combination (ACT) therapy is the mainstay for malaria treatment. However, Plasmodium parasite with decreased susceptibility to ACT has emerged. Hence, it is imperative to discover new drugs or explore new drug combinations that can
Externí odkaz:
https://doaj.org/article/09dd23abbb4e4f1e9afeb117742c51ee
Publikováno v:
Trends in Pharmaceutical Sciences, Vol 7, Iss 1, Pp 49-58 (2021)
The clinical use of paclitaxel (PCL) may cause nephrotoxicity. Antioxidants have shown potential benefits in some disease conditions. This study examined the protective abilities of coenzyme Q10 (CoQ10) and resveratrol (RSV) against PCL-induced nephr
Externí odkaz:
https://doaj.org/article/613a5944b0254ecda38cb6be7be1783b
Autor:
Elias Adikwu, Ebiladei Liverpool
Publikováno v:
Journal of Nature and Science of Medicine, Vol 4, Iss 2, Pp 118-123 (2021)
Background: The use of valproic acid (VPA) as therapy for epileptic and other neuropsychiatric disorders may cause hepatotoxicity. Selenium (Se), a component of selenoproteins, which performs important enzymic functions, may protect biomolecules from
Externí odkaz:
https://doaj.org/article/146d7587e8054993b9ab73974d09eda6
Publikováno v:
Journal of Medical Sciences, Vol 41, Iss 3, Pp 116-122 (2021)
Background: Treatment modalities for Fanconi syndrome caused by ifosfamide (IFO) are very limited. This study assessed the protective effect of lycopene (LYP) against IFO-induced Fanconi syndrome in albino rats. Methods: Forty adult male albino rats
Externí odkaz:
https://doaj.org/article/907257352b6c42d88ae6d42657bbbdba
Publikováno v:
Journal of Marine Medical Society, Vol 23, Iss 1, Pp 47-51 (2021)
Background: The therapeutic benefit of tenofovir/lamivudine/efavirenz (TLE) in the treatment of human immunodeficiency virus can be truncated by the occurrence of hepatotoxicity. This study evaluated the protective effect of selenium (Se) against hep
Externí odkaz:
https://doaj.org/article/0a693aa5f5a34b178b0aed977217b35e