Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Elianna Amin"'
Autor:
Daima Bukini, Julie Makani, Joseph McCune, Dennis Lee, Cathy Bansbach, Serena De Vita, Dominic Kemps, Elianna Amin, Jonathan Spector, John Tisdale
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 3, Pp 101287- (2024)
Therapeutic innovation to address sickle cell disease (SCD) is at a historical apex, characterized by a drug discovery, development, and commercialization landscape that includes potentially curative gene therapies. Given the wide geographic distribu
Externí odkaz:
https://doaj.org/article/61e617179782482faff6d68ead4aa67b
Autor:
James Taggart, Tzu-Chieh Ho, Elianna Amin, Haiming Xu, Trevor S. Barlowe, Alexendar R. Perez, Benjamin H. Durham, Patrick Tivnan, Rachel Okabe, Arthur Chow, Ly Vu, Sun Mi Park, Camila Prieto, Christopher Famulare, Minal Patel, Christopher J. Lengner, Amit Verma, Gail Roboz, Monica Guzman, Virginia M. Klimek, Omar Abdel-Wahab, Christina Leslie, Stephen D. Nimer, Michael G. Kharas
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Several studies have recently demonstrated the role of the MSI2 RNA binding protein in normal and malignant haematopoietc stem cells. In this study, the authors show that MSI2 is required for maintaining myelodysplastic syndrome stem cells in mice an
Externí odkaz:
https://doaj.org/article/3c73f9725b9740dfbe30b10dcaac4d49
Autor:
Amit Verma, Michael G. Kharas, H. Joachim Deeg, Marc H.G.P. Raaijmakers, Ulrich Steidl, Britta Will, Jacqueline Boultwood, Andrea Pellagatti, Siddhartha Mukherjee, John M. Greally, Jinghang Zhang, Kith Pradhan, Yiting Yu, Konrad Hochedlinger, Peter Aplan, Kira Gritsman, Cecilia Yeung, Amittha Wickrema, Davendra Sohal, Orsi Giricz, Prafulla Bhagat, Robert Lopez, Remi Laurence, Vineeth Sukrithan, Iaonnis Mantzaris, Nandini Ramachandra, Suman Kambhampati, Remco M. Hoogenboezem, Mathijs A. Sanders, A. Mario Marcondes, Elianna Amin, Patrick Tivnan, Gaurav S. Choudhary, Dagny Von Ahrens, A. Trevor Barlowe, Matthias Bartenstein, Si Chen, Tushar D. Bhagat
Supp Table 1: MDS Patient Disease Characteristics Supp Table 2: Pathways affected by hypermethylation in MDS stroma Supp Table 3: Genes that are methylated and underexpressed in MDS stroma Supp Table 4. MDS patient characteristics for primary MSC sam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dae0ab1066c8473f458390b001954c2
https://doi.org/10.1158/0008-5472.22414418.v1
https://doi.org/10.1158/0008-5472.22414418.v1
Autor:
Amit Verma, Michael G. Kharas, H. Joachim Deeg, Marc H.G.P. Raaijmakers, Ulrich Steidl, Britta Will, Jacqueline Boultwood, Andrea Pellagatti, Siddhartha Mukherjee, John M. Greally, Jinghang Zhang, Kith Pradhan, Yiting Yu, Konrad Hochedlinger, Peter Aplan, Kira Gritsman, Cecilia Yeung, Amittha Wickrema, Davendra Sohal, Orsi Giricz, Prafulla Bhagat, Robert Lopez, Remi Laurence, Vineeth Sukrithan, Iaonnis Mantzaris, Nandini Ramachandra, Suman Kambhampati, Remco M. Hoogenboezem, Mathijs A. Sanders, A. Mario Marcondes, Elianna Amin, Patrick Tivnan, Gaurav S. Choudhary, Dagny Von Ahrens, A. Trevor Barlowe, Matthias Bartenstein, Si Chen, Tushar D. Bhagat
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7088e12509540b55682090ae288f6768
https://doi.org/10.1158/0008-5472.22414421
https://doi.org/10.1158/0008-5472.22414421
Autor:
Amit Verma, Michael G. Kharas, H. Joachim Deeg, Marc H.G.P. Raaijmakers, Ulrich Steidl, Britta Will, Jacqueline Boultwood, Andrea Pellagatti, Siddhartha Mukherjee, John M. Greally, Jinghang Zhang, Kith Pradhan, Yiting Yu, Konrad Hochedlinger, Peter Aplan, Kira Gritsman, Cecilia Yeung, Amittha Wickrema, Davendra Sohal, Orsi Giricz, Prafulla Bhagat, Robert Lopez, Remi Laurence, Vineeth Sukrithan, Iaonnis Mantzaris, Nandini Ramachandra, Suman Kambhampati, Remco M. Hoogenboezem, Mathijs A. Sanders, A. Mario Marcondes, Elianna Amin, Patrick Tivnan, Gaurav S. Choudhary, Dagny Von Ahrens, A. Trevor Barlowe, Matthias Bartenstein, Si Chen, Tushar D. Bhagat
The bone marrow microenvironment influences malignant hematopoiesis, but how it promotes leukemogenesis has not been elucidated. In addition, the role of the bone marrow stroma in regulating clinical responses to DNA methyltransferase inhibitors (DNM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f33ca2e7ce5f82dc31f12f52089be88
https://doi.org/10.1158/0008-5472.c.6508973.v1
https://doi.org/10.1158/0008-5472.c.6508973.v1
Autor:
Amit Verma, Michael G. Kharas, H. Joachim Deeg, Marc H.G.P. Raaijmakers, Ulrich Steidl, Britta Will, Jacqueline Boultwood, Andrea Pellagatti, Siddhartha Mukherjee, John M. Greally, Jinghang Zhang, Kith Pradhan, Yiting Yu, Konrad Hochedlinger, Peter Aplan, Kira Gritsman, Cecilia Yeung, Amittha Wickrema, Davendra Sohal, Orsi Giricz, Prafulla Bhagat, Robert Lopez, Remi Laurence, Vineeth Sukrithan, Iaonnis Mantzaris, Nandini Ramachandra, Suman Kambhampati, Remco M. Hoogenboezem, Mathijs A. Sanders, A. Mario Marcondes, Elianna Amin, Patrick Tivnan, Gaurav S. Choudhary, Dagny Von Ahrens, A. Trevor Barlowe, Matthias Bartenstein, Si Chen, Tushar D. Bhagat
Supp Fig 1 : SFRP1 methylation with coculture Supp Fig 2 : Validation of methylation changes with stroma and leukemic cell coculture Supp Fig 3: FRZB upregulation in MDS stroma after 5-Azacytidine treatment SuppFig 4: FRZB knockdown leads to partial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0489f392c2b7fdad35acf602880e9cba
https://doi.org/10.1158/0008-5472.22414424.v1
https://doi.org/10.1158/0008-5472.22414424.v1