Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Eliane Duroux"'
Autor:
M. Madesclaire, Catherine Rubat, Valérie Weber, Pascal Coudert, Claire Lartigue, Eliane Duroux
Publikováno v:
Bioorganic & Medicinal Chemistry. 13:4552-4564
Two series of new furanones substituted by methylsulfonylphenyl or methylsulfamidophenyl moieties were found to protect against oxidation damage by inhibiting or quenching free radicals and reactive oxygen species in in vitro experiments. The effect
Autor:
Daniel Gardette, Jean Claude Gramain, M. Madesclaire, Eliane Duroux, Danielle Vallee-Goyet, Pascal Coudert, Fernand Leal, Marc Bria, Jacques Couquelet, Valérie Weber, Eliane Albuisson, Catherine Rubat
Publikováno v:
Bioorganic & Medicinal Chemistry. 10:1647-1658
In order to study the effect of phenol moieties on biological activities of ascorbic acid derivatives, we synthesized 13 novel 4,5-diaryl-3-hydroxy-2(5H)-furanones 5a-m with various substitution patterns. Compound 5 g bearing a 2,3-dihydroxy phenyl r
Autor:
Catherine Rubat, Eliane Duroux, Pascal Coudert, Jacques Couquelet, Fernand Leal, Valérie Weber
Publikováno v:
Journal of Pharmacy and Pharmacology. 52:523-530
Structural modifications of ascorbic acid by the introduction of lipophilic moieties has led to derivatives with increased stability against thermal and oxidative degradation. Two series of new lipophilic ascorbic analogues were synthesized to obtain
Autor:
Joseph Fialip, Axel Béal, Eliane Duroux, Nicolas Authier, Delphine Guillaume, François Coudoré
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 721:317-320
A simple and sensitive high-performance liquid chromatographic method is described for the determination of paclitaxel (Taxol) at 230 nm using a Nucleosil C18 (5 microm) column and a methanol-water (70:30, v/v) mobile phase following a single-step ex
Autor:
Fernand Leal, M. Madesclaire, Valérie Weber, Jacques Couquelet, Pascal Coudert, Eliane Duroux
Publikováno v:
ChemInform. 33
The antioxidant properties of eleven α-pyrones and four γ-pyrones were evaluated by means of three different tests: reduction of the stable free radical, 1,1-diphenyl-2-picrylhydrazyl (DPPH), superoxide anion scavenging assay and lipid peroxidation
Autor:
M. Madesclaire, Fernand Leal, Valérie Weber, Pascal Coudert, Jacques Couquelet, Eliane Duroux
Publikováno v:
Scopus-Elsevier
The antioxidant properties of eleven α-pyrones and four γ-pyrones were evaluated by means of three different tests: reduction of the stable free radical, 1,1-diphenyl-2-picrylhydrazyl (DPPH), superoxide anion scavenging assay and lipid peroxidation
Publikováno v:
Neuroreport. 8(4)
The influence of tolcapone, an inhibitor of catechol-O-methyl transferase, was evaluated on the disposition of apomorphine, a dopamine agonist used to treat Parkinson's disease, to explain a previously observed increase of duration of the effect of a
Publikováno v:
Biologicalpharmaceutical bulletin. 19(2)
Ascorbic acid, present in plasma from humans at concentrations of 50 to 200 mumol/l, has multiple antioxidant properties. Structural modification of this vitamin by the introduction of lipophilic moieties has allowed to the development of ascorbate e
Autor:
Pascal Coudert, Sylvie Mavel, P. Bastide, Catherine Rubat, P. Tronche, Jacques Couquelet, Eliane Albuisson, Eliane Duroux
Publikováno v:
Chemicalpharmaceutical bulletin. 40(6)
N-Acetic acid derivatives of 6-aryl-pyrazolo-triazin-4-ones were synthesized for evaluation as new aldose reductase inhibitors. The intrinsic activity of each compound was assessed by measuring the inhibition of enzymatic activity in an isolated pig