Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Eliane C. Arantes"'
Autor:
Caio B. Abreu, Karla C. F. Bordon, Felipe A. Cerni, Isadora S. Oliveira, Carla Balenzuela, Gabriel M. Alexandre-Silva, Karina F. Zoccal, Mouzarllem B. Reis, Gisele A. Wiezel, Steve Peigneur, Ernesto L. Pinheiro-Júnior, Jan Tytgat, Tiago M. Cunha, Loic Quinton, Lúcia H. Faccioli, Eliane C. Arantes, Umberto Zottich, Manuela B. Pucca
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Scorpionism is responsible for most accidents involving venomous animals in Brazil, which leads to severe symptoms that can evolve to death. Scorpion venoms consist of complexes cocktails, including peptides, proteins, and non-protein compounds, maki
Externí odkaz:
https://doaj.org/article/304b81820cb3475fab32a23a0e518028
Autor:
Manuela B. Pucca, Shirin Ahmadi, Felipe A. Cerni, Line Ledsgaard, Christoffer V. Sørensen, Farrell T. S. McGeoghan, Trenton Stewart, Erwin Schoof, Bruno Lomonte, Ulrich auf dem Keller, Eliane C. Arantes, Figen Çalışkan, Andreas H. Laustsen
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Toxin synergism is a complex biochemical phenomenon, where different animal venom proteins interact either directly or indirectly to potentiate toxicity to a level that is above the sum of the toxicities of the individual toxins. This provides the an
Externí odkaz:
https://doaj.org/article/f708fbc151bd4462b01ad31680dc485f
Autor:
Karina F. Zoccal, Luiz G. Gardinassi, Karla C. F. Bordon, Eliane C. Arantes, Sylvie Marleau, Huy Ong, Lúcia H. Faccioli
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Over 1 million cases of scorpion stings are estimated every year, whereas current treatment is limited to antivenom serum combined with supportive therapy. Tityus serrulatus scorpion venom (TsV) is composed of diverse molecules, including toxins that
Externí odkaz:
https://doaj.org/article/51d187fa6211407a92e65c8a6d1a5ab0
Autor:
Karina F. Zoccal, Carlos A. Sorgi, Juliana I. Hori, Francisco W. G. Paula-Silva, Eliane C. Arantes, Carlos H. Serezani, Dario S. Zamboni, Lúcia H. Faccioli
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Scorpion venom causes thousands of deaths worldwide. Here the authors show that the envenomation acts via prostaglandin E2 leading to inflammasome activation and lung pathology, counterbalanced by inflammation-limiting LTB4, and that COX inhibitors o
Externí odkaz:
https://doaj.org/article/e5a78ff56bba431db5aa20e5f7cb0854
Autor:
Shirin Ahmadi, Julius M. Knerr, Lídia Argemi, Karla C. F. Bordon, Manuela B. Pucca, Felipe A. Cerni, Eliane C. Arantes, Figen Çalışkan, Andreas H. Laustsen
Publikováno v:
Biomedicines, Vol 8, Iss 5, p 118 (2020)
Scorpion venom may cause severe medical complications and untimely death if injected into the human body. Neurotoxins are the main components of scorpion venom that are known to be responsible for the pathological manifestations of envenoming. Beside
Externí odkaz:
https://doaj.org/article/beb066f6390848d891013a7e96a5c4e1
Autor:
Christoffer V. Sørensen, Cecilie Knudsen, Ulrich auf dem auf dem Keller, Konstantinos Kalogeropoulos, Cristina Gutiérrez-Jiménez, Manuela B. Pucca, Eliane C. Arantes, Karla C. F. Bordon, Andreas H. Laustsen
Publikováno v:
Toxins, Vol 12, Iss 4, p 240 (2020)
Antibiotics are often administered with antivenom following snakebite envenomings in order to avoid secondary bacterial infections. However, to this date, no studies have evaluated whether antibiotics may have undesirable potentiating effects on snak
Externí odkaz:
https://doaj.org/article/66fd5242d24c40cd89e3ffb2ae989b2c
Autor:
Karina F. Zoccal, Luiz G. Gardinassi, Carlos A. Sorgi, Alyne F. G. Meirelles, Karla C. F. Bordon, Isaias Glezer, Palmira Cupo, Alessandra K. Matsuno, Valdes R. Bollela, Eliane C. Arantes, Francisco S. Guimarães, Lúcia Helena Faccioli
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Interleukin (IL)-1β is a potential target for treatment of several inflammatory diseases, including envenomation by the scorpion Tityus serrulatus. In this context, bioactive lipids such as prostaglandin (PG)E2 and leukotriene (LT)B4 modulate the pr
Externí odkaz:
https://doaj.org/article/cdaa09a9843e475a81ad60014e7228e0
Autor:
Manuela B. Pucca, Felipe A. Cerni, Steve Peigneur, Karla C. F. Bordon, Jan Tytgat, Eliane C. Arantes
Publikováno v:
Toxins, Vol 7, Iss 7, Pp 2534-2550 (2015)
The toxin, previously described as a “non-toxic” toxin, was isolated from the scorpion venom of Tityus serrulatus (Ts), responsible for the most severe and the highest number of accidents in Brazil. In this study, the subtype specificity and sele
Externí odkaz:
https://doaj.org/article/de28f0fea03c44e1a6a2a27a49fb82d3
Autor:
Welligton M. Santussi, Karla C. F. Bordon, Ana P. N. Rodrigues Alves, Camila T. Cologna, Suraia Said, Eliane C. Arantes
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Antimicrobial peptides (AMPs) are ubiquitous and multipotent components of the innate immune defense arsenal used by both prokaryotic and eukaryotic organisms. The search for new AMPs has increased in recent years, due to the growing development of m
Externí odkaz:
https://doaj.org/article/ffc15704d96a4cb8b4f97145a9183b56
Autor:
Felipe A. Cerni, Manuela B. Pucca, Steve Peigneur, Caroline M. Cremonez, Karla C. F. Bordon, Jan Tytgat, Eliane C. Arantes
Publikováno v:
Toxins, Vol 6, Iss 3, Pp 892-913 (2014)
In Brazil, Tityus serrulatus (Ts) is the species responsible for most of the scorpion related accidents. Among the Ts toxins, the neurotoxins with action on potassium channels (α-KTx) present high interest, due to their effect in the envenoming proc
Externí odkaz:
https://doaj.org/article/55b5c90d9072442bb61e87460506a909