Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Eliana Trapani"'
Autor:
Cinzia Antognelli, Eliana Trapani, Simona Delle Monache, Andrea Perrelli, Claudia Fornelli, Francesca Retta, Paola Cassoni, Vincenzo Nicola Talesa, Saverio Francesco Retta
Publikováno v:
Data in Brief, Vol 16, Iss , Pp 929-938 (2018)
This article contains additional data related to the original research article entitled “KRIT1 loss-of-function induces a chronic Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: implication for Cerebral Cavernous Malfo
Externí odkaz:
https://doaj.org/article/7c97ed754cb04cf9853be2257185f359
Autor:
Luca Goitre, Peter V. DiStefano, Andrea Moglia, Nicholas Nobiletti, Eva Baldini, Lorenza Trabalzini, Julie Keubel, Eliana Trapani, Vladimir V. Shuvaev, Vladimir R. Muzykantov, Ingrid H. Sarelius, Saverio Francesco Retta, Angela J. Glading
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract The intracellular scaffold KRIT1/CCM1 is an established regulator of vascular barrier function. Loss of KRIT1 leads to decreased microvessel barrier function and to the development of the vascular disorder Cerebral Cavernous Malformation (CC
Externí odkaz:
https://doaj.org/article/6fc3adc7ae70457492848b492ff196e1
Autor:
Saverio Marchi, Mariangela Corricelli, Eliana Trapani, Luca Bravi, Alessandra Pittaro, Simona Delle Monache, Letizia Ferroni, Simone Patergnani, Sonia Missiroli, Luca Goitre, Lorenza Trabalzini, Alessandro Rimessi, Carlotta Giorgi, Barbara Zavan, Paola Cassoni, Elisabetta Dejana, Saverio Francesco Retta, Paolo Pinton
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 11, Pp 1403-1417 (2015)
Abstract Cerebral cavernous malformation (CCM) is a major cerebrovascular disease affecting approximately 0.3–0.5% of the population and is characterized by enlarged and leaky capillaries that predispose to seizures, focal neurological deficits, an
Externí odkaz:
https://doaj.org/article/5b50193f8a5849aebd091244eb7e131d
Autor:
Simona Delle Monache, Stefania Pizzimenti, Adriano Angelucci, Vincenzo Nicola Talesa, Martina Daga, Andrea Perrelli, Paola Cassoni, Lorenza Trabalzini, Eliana Trapani, Giuseppina Barrera, Luca Goitre, Saverio Francesco Retta, Cinzia Antognelli
Publikováno v:
Free Radical Biology & Medicine
KRIT1 (CCM1) is a disease gene responsible for Cerebral Cavernous Malformations (CCM), a major cerebrovascular disease of proven genetic origin affecting 0.3–0.5% of the population. Previously, we demonstrated that KRIT1 loss-of-function is associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9626ca3388471d5ac6e4cae96d0dfe5e
http://hdl.handle.net/2318/1663006
http://hdl.handle.net/2318/1663006
Autor:
Andrea Perrelli, Eliana Trapani, Cinzia Antognelli, Simona Delle Monache, Claudia Fornelli, Valerio Benedetti, Giulia Costantino, Federica Geddo, Alessia Zotta, Sara Sarri, Giovanna Bratti, Luca Goitre, Saverio Francesco Retta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ac30f9a70f0732a8afa2d3c9c6f59d
http://hdl.handle.net/11391/1453936
http://hdl.handle.net/11391/1453936
Autor:
Eliana Trapani, Saverio Francesco Retta, Vincenzo Nicola Talesa, Lorenza Trabalzini, Cinzia Antognelli, Andrea Perrelli, Giuseppina Barrera, Sara Sarri, Luca Goitre
Cerebral Cavernous Malformation (CCM) is a major cerebrovascular disease of genetic origin affecting 0.3-0.5% of the population and still awaiting therapies other than neurosurgery. It is characterized by abnormally enlarged and leaky capillaries, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91faea31c8d4bad57d5d2a31692fc73d
http://hdl.handle.net/2318/1723206
http://hdl.handle.net/2318/1723206
Autor:
Eliana Trapani, Fiorella Biasi, Federica Geddo, Andrea Perrelli, Raffaella Mastrocola, Giulia Costantino, Enrica Boda, Claudia Fornelli, Luca Goitre, Alessia Zotta, Saverio Francesco Retta, Valerio Benedetti
Cerebral Cavernous Malformation (CCM) is a major cerebrovascular disease with a prevalence of 0.3–0.5% in the general population and highly variable clinical expressivity. It may cause various symptoms at any age, including recurrent headaches, neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6fe4e700bc6b580e8b066ba489fc256
http://hdl.handle.net/2318/1723210
http://hdl.handle.net/2318/1723210
Autor:
Eva Baldini, Eliana Trapani, Jules Beekwilder, Antonella Scattina, Silvia Gianoglio, Giancarlo Dondo, Saverio Francesco Retta, Andrea Genre, Andrea Moglia, Lorenza Trabalzini, Luca Goitre
Publikováno v:
BioFactors. 41:15-27
Saccharomyces cerevisiae has been proven to be a valuable tool for the expression of plant metabolic pathways. By engineering a S. cerevisiae strain with two plant genes (4cl-2 from tobacco and hct from globe artichoke) we previously set up a system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::229bcfabad9d7105af607fc12e3159cd
https://doi.org/10.1002/biof.1197
https://doi.org/10.1002/biof.1197
Autor:
Stefano Braggion, Luca Goitre, Andrea Moglia, Lorenza Trabalzini, Michela Guglielmotto, Eliana Trapani, Marco Forni, Fiorella Biasi, Saverio Francesco Retta, Elisa De Luca
Publikováno v:
Free Radical Biology & Medicine
Loss-of-function mutations in the KRIT1 gene (CCM1) have been associated with the pathogenesis of cerebral cavernous malformations (CCM), a major cerebrovascular disease. However, KRIT1 functions and CCM pathogenetic mechanisms remain incompletely un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37cfe58d6ce868e505bb880df82f17f4
https://doi.org/10.1016/j.freeradbiomed.2013.11.020
https://doi.org/10.1016/j.freeradbiomed.2013.11.020
Autor:
Eliana Trapani, Leslie Morrison, Helen Kim, Blaine L. Hart, Amy Akers, Hélène Choquet, Lorenza Trabalzini, Saverio Francesco Retta, Marco Maria Fontanella, Ludmila Pawlikowska, Luca Goitre
Publikováno v:
Free Radical Biology & Medicine
Background Familial Cerebral Cavernous Malformation type 1 (CCM1) is an autosomal dominant disease caused by mutations in the Krev Interaction Trapped 1 (KRIT1/CCM1) gene, and characterized by multiple brain lesions. CCM lesions manifest across a ran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88d84c4e775795015bd548fd69c3791e
http://hdl.handle.net/11379/533891
http://hdl.handle.net/11379/533891