Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Eliana M C, Tacconi"'
Autor:
Filipa Landeiro, DPhil, Callum Harris, MA BMBCH, David Groves, MSc, Samuel O’Neill, MBBS, Kuljinder Singh Jandu, MBChB, Eliana M C Tacconi, DPhil, Samantha Field, MSc, Nileema Patel, MSc, Anya Göpfert, MSc, Hannes Hagson, MSc, José Leal, DPhil, Ramón Luengo-Fernández, DPhil
Publikováno v:
The Lancet. Healthy Longevity, Vol 5, Iss 8, Pp e514-e523 (2024)
Summary: Background: Cancer, coronary heart disease, dementia, and stroke are major contributors to morbidity and mortality in England. We aimed to assess the economic burden (including health-care, social care, and informal care costs, as well as pr
Externí odkaz:
https://doaj.org/article/2199e22368984b8fa996887a89f33110
A transcription-based mechanism for oncogenic β-catenin-induced lethality in BRCA1/2-deficient cells
Autor:
Rebecca A. Dagg, Gijs Zonderland, Emilia Puig Lombardi, Giacomo G. Rossetti, Florian J. Groelly, Sonia Barroso, Eliana M. C. Tacconi, Benjamin Wright, Helen Lockstone, Andrés Aguilera, Thanos D. Halazonetis, Madalena Tarsounas
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Germline mutations in BRCA1 or BRCA2 tumour suppressor genes predispose to different cancers, as does oncogene activation. Here the authors reveal that aberrant transcription of specific genes triggered by activation of the oncogene β-catenin causes
Externí odkaz:
https://doaj.org/article/df2c21948aa4474d8a16c5c108679eec
Autor:
Jutta, Zimmer, Eliana M C, Tacconi, Cecilia, Folio, Sophie, Badie, Manuela, Porru, Kerstin, Klare, Manuela, Tumiati, Enni, Markkanen, Swagata, Halder, Anderson, Ryan, Stephen P, Jackson, Kristijan, Ramadan, Sergey G, Kuznetsov, Annamaria, Biroccio, Julian E, Sale, Madalena, Tarsounas
Publikováno v:
Molecular Cell
Summary G-quadruplex (G4)-forming genomic sequences, including telomeres, represent natural replication fork barriers. Stalled replication forks can be stabilized and restarted by homologous recombination (HR), which also repairs DNA double-strand br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c7cfbefbdb30f2e35eaad021b8a9a7a
https://pubmed.ncbi.nlm.nih.gov/26748828
https://pubmed.ncbi.nlm.nih.gov/26748828