Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Eliana H. Akamine"'
Autor:
Davide Di Bella, João P. S. Ferreira, Renee de Nazare O. Silva, Cinthya Echem, Aline Milan, Eliana H. Akamine, Maria H. Carvalho, Stephen F. Rodrigues
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-15 (2021)
Abstract Background Sepsis is an emergency medical condition that can lead to death and it is defined as a life-threatening organ dysfunction caused by immune dysregulation in response to an infection. It is considered the main killer in intensive ca
Externí odkaz:
https://doaj.org/article/e98cb7baf0a94dc9b0a00f72a76aff3b
Publikováno v:
Frontiers in Aging, Vol 2 (2021)
Increasing scientific interest has been directed to sex as a biological and decisive factor on several diseases. Several different mechanisms orchestrate vascular function, as well as vascular dysfunction in cardiovascular and metabolic diseases in m
Externí odkaz:
https://doaj.org/article/87e65d68b1314f29ac667f0b0ee74c19
Autor:
Tiago J. Costa, Josiane F. Silva, Renée de Nazaré O. da Silva, Paula R. Barros, Juliana Bolsoni, Daniel Rodrigues, Eliana H. Akamine, Rita Tostes
Publikováno v:
Artery Research, Vol 25, Iss 1 (2020)
The glycosylation with O-linked-N-acetylglucosamine (O-GlcNAc) is an enzymatic process found on nuclear and cytoplasmic proteins. Augmented levels of O-GlcNAc-modified proteins have been associated to cardiovascular disease (CD) in male. However, the
Externí odkaz:
https://doaj.org/article/4b61a77854cc44c5ab704496ee59139c
Autor:
Mayara C. F. Gewehr, Alexandre A. S. Teixeira, Bruna A. C. Santos, Luana A. Biondo, Fábio C. Gozzo, Amanda M. Cordibello, Rosangela A. S. Eichler, Patrícia Reckziegel, Renée N. O. Da Silva, Nilton B. Dos Santos, Niels O. S. Camara, Angela Castoldi, Maria L. M. Barreto-Chaves, Camila S. Dale, Nathalia Senger, Joanna D. C. C. Lima, Marilia C. L. Seelaender, Aline C. Inada, Eliana H. Akamine, Leandro M. Castro, Alice C. Rodrigues, José C. Rosa Neto, Emer S. Ferro
Publikováno v:
Biomolecules, Vol 10, Iss 2, p 321 (2020)
Thimet oligopeptidase (EC 3.4.24.15; EP24.15; THOP1) is a potential therapeutic target, as it plays key biological functions in processing biologically functional peptides. The structural conformation of THOP1 provides a unique restriction regarding
Externí odkaz:
https://doaj.org/article/cd23c3a4fd914795937480a86869742c
Autor:
Tiago J. Costa, Graziela S. Ceravolo, Cinthya Echem, Carolina M. Hashimoto, Beatriz P. Costa, Rosangela A. Santos-Eichler, Maria Aparecida Oliveira, Francesc Jiménez-Altayó, Eliana H. Akamine, Ana Paula Dantas, Maria Helena C. Carvalho
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Postmenopausal period has been associated to different symptoms such as hot flashes, vulvovaginal atrophy, hypoactive sexual desire disorder (HSDD) and others. Clinical studies have described postmenopausal women presenting HSDD can benefit from the
Externí odkaz:
https://doaj.org/article/a1dbf904d2e1496395afad85210092a7
Autor:
Tiago J. Costa, Paula R. Barros, Diego A. Duarte, Júlio A. Silva-Neto, Sara Cristina Hott, Thamyris Santos-Silva, Claudio M. Costa-Neto, Felipe V. Gomes, Eliana H. Akamine, Cameron G. McCarthy, Francesc Jimenez-Altayó, Ana Paula Dantas, Rita C. Tostes
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 324:H417-H429
The present study provides evidence that senescence induces hyperreactivity of α1-adrenoceptor-mediated contraction of the common carotid. Impairment of α1-adrenoceptor responses is linked to increased Ca2+ influx and release of COX-derived vasocon
Autor:
Eduardo H Moretti, Abner C Rodrigues, Bruno V Marques, Leonardo T Totola, Caroline B Ferreira, Camila F Brito, Caroline M Matos, Filipe A da Silva, Robson A S Santos, Luciana B Lopes, Thiago S Moreira, Eliana H Akamine, Luiz A Baccala, André Fujita, Alexandre A Steiner
Publikováno v:
PNAS Nexus. 2
Uncontrolled vasodilation is known to account for hypotension in the advanced stages of sepsis and other systemic inflammatory conditions, but the mechanisms of hypotension in earlier stages of such conditions are not clear. By monitoring hemodynamic
Autor:
Simone M, Sartoretto, Rosângela, Santos-Eichler, Rita, de Cássia A Tostes, Maria Helena C, Carvalho, Eliana H, Akamine, Zuleica B, Fortes
Publikováno v:
Journal of diabetes. 5(2)
Diabetes differentially affects the vascular system in males and females. Although various results have been reported, very few studies have focused on responses in females. In the present study, we investigated contractile responses to norepinephrin
Autor:
Maria do Carmo P, Franco, Zuleica B, Fortes, Eliana H, Akamine, Elisa M, Kawamoto, Cristoforo, Scavone, Luiz Roberto Giorgetti, de Britto, Marcelo N, Muscara, Simone A, Teixeira, Rita C A, Tostes, Maria Helena C, Carvalho, Dorothy, Nigro
Publikováno v:
The Journal of physiology. 558(Pt 1)
In the present study, we investigated the effects of the exogenous application of tetrahydrobiopterin on the endothelium-dependent vasorelaxation and superoxide anion generation in the mesenteric microvessels of intrauterine undernourished rats. In a
Autor:
Eveline A. I. Fonseca, Maria Aparecida Oliveira, Rosangela Eichler, Eliana H. Akamine, Maria Helena C. Carvalho, Aneli M. Barbosa, Robert F. H. Dekker, Neelam Khaper, Zuleica B. Fortes
Publikováno v:
Cancer Research. 73:PR15-PR15
Epidemiological studies have associated obesity with a wide variety of cancers such as metastatic breast cancer. Insulin resistance and hyperinsulinemia have been proposed as the mechanisms by which obesity induces or promotes tumorigenesis. Metformi