Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Eliana Clark"'
Autor:
Nikunja Kolluri, Gardner Noah Paul, Eliana Clark, Shreelekha Jaligama, Vinita Doshi, Riley Cole, Jason Zarate, Chris Luby, Justin Eng, Kristy Wood, Shloka Aiyer, Casey Kimball, Daniel Cossette
Publikováno v:
Blood. 138:3881-3881
Adoptive T cell therapy has shown exciting efficacy in the treatment of certain hematological malignancies, particularly B cell tumors. However, with other cancers there has been limited success to date, and there remain significant challenges to dev
Publikováno v:
Epilepsia. 53:142-149
To gain insights into the phenotype of Kv1.1 and Kv4.2 knockout mice, we used immunohistochemistry to analyze expression of component principal or α subunits and auxiliary subunits of neuronal Kv channels in knockout mouse brains. Genetic ablation o
Autor:
Eliana Clark, John R. L. Constable, Faten El-Sabeawy, Philip Washbourne, A. Kimberley McAllister, Stephanie L. Barrow
Publikováno v:
Neural Development, Vol 4, Iss 1, p 17 (2009)
Neural Development
Neural Development
Background The cell adhesion molecule pair neuroligin1 (Nlg1) and β-neurexin (β-NRX) is a powerful inducer of postsynaptic differentiation of glutamatergic synapses in vitro. Because Nlg1 induces accumulation of two essential components of the post
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 104(50)
Kv1.2 α-subunits are components of low-threshold, rapidly activating voltage-gated potassium (Kv) channels in mammalian neurons. Expression and localization of Kv channels is regulated by trafficking signals encoded in their primary structure. Kv1.2
Autor:
Eliana Clark, Robert M. Sapolsky, H. Jürgen Wenzel, Helene Vacher, Bruce L. Tempel, Angela L. Lee, Philip A. Schwartzkroin, James S. Trimmer
Publikováno v:
Epilepsia. 48(11)
Summary Purpose: Mice lacking the Kv1.1 potassium channel α subunit encoded by the Kcna1 gene develop recurrent behavioral seizures early in life. We examined the neuropathological consequences of seizure activity in the Kv1.1−/− (knock-out) mou
Publikováno v:
Neuron. 52(3)
In the October 6th issue of Science , Raab-Graham et al. described two surprising findings. They discovered that local dendritic translation of Kv1.1 occurs in CA1 dendrites of rat hippocampal slices and in cultured neurons. This local translation is
Publikováno v:
Neuron. 40(3)
Voltage-gated channels operate through the action of a voltage-sensing domain (membrane segments S1-S4) that controls the conformation of gates located in the pore domain (membrane segments S5-S6). Recent structural studies on the bacterial KvAP pota