Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Eliana C. De Benedetti"'
Publikováno v:
Journal of biotechnology. 323
Cladribine (2-chloro-2′-deoxy-β- d -adenosine) is a 2′-deoxyadenosine analogue, approved by the FDA for the treatment of hairy cell leukemia and more recently has been proved for therapeutic against many autoimmune diseases as multiple sclerosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abc4cc60301171973d29e9bdbdea154e
https://pubmed.ncbi.nlm.nih.gov/32841608
https://pubmed.ncbi.nlm.nih.gov/32841608
Publikováno v:
Process Biochemistry (Barking, London, England)
Graphical abstract
Highlights • Biotransformation of ribavirin was performed by E. coli ATCC 12407, reaching yields of 86%. • This mesophile microorganism was successfully stabilized in agarose and polyacrylamide. • Biocatalyst immobilized
Highlights • Biotransformation of ribavirin was performed by E. coli ATCC 12407, reaching yields of 86%. • This mesophile microorganism was successfully stabilized in agarose and polyacrylamide. • Biocatalyst immobilized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb27344ddffc05f0e66f4ec3c5a285e7
http://europepmc.org/articles/PMC7108421
http://europepmc.org/articles/PMC7108421
Autor:
Eliana C. De Benedetti, Jose M. Guisan, Jorge A. Trelles, Fernando López Gallego, Benevides C. C. Pessela, Cintia W. Rivero
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Ribavirin is a synthetic guanosine analogue with a broad-spectrum of antiviral activity. It is clinically effective against several viruses, such as respiratory syncytial virus, several hemorrhagic fever viruses and HCV when combined with pegylated i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed20bda4f28b8976d16faeb6605e5674
https://pubmed.ncbi.nlm.nih.gov/28347766
https://pubmed.ncbi.nlm.nih.gov/28347766
Autor:
Eliana C. De Benedetti, Jorge A. Trelles, Cintia W. Rivero, Mario Enrique Lozano, Claudia N. Britos
Publikováno v:
Biotechnology Progress. 28:1251-1256
An efficient and green bioprocess to obtain 2,6-diaminopurine nucleosides using thermophilic bacteria is herein reported. Geobacillus stearothermophilus CECT 43 showed a conversion rate of 90 and 83% at 2 h to obtain 2,6-diaminopurine-2 0 -deoxyribos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c412cd6167bd722c074d2d3dbf3ba7c4
https://doi.org/10.1002/btpr.1602
https://doi.org/10.1002/btpr.1602
Ribavirin is a guanosine analogue commonly used as an antiviral compound for the treatment of Hepatitis C virus (HCV) infection. The biosynthesis of this compound using Geobacillus kaustophilus ATCC 8005 as biocatalyst is herein reported. This extrem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5368fd7482d75e74aaebddced0611137
https://www.sciencedirect.com/science/article/pii/S1381117715300448
https://www.sciencedirect.com/science/article/pii/S1381117715300448
Autor:
Mario Enrique Lozano, Eliana C. De Benedetti, Jorge Enrique Sambeth, Cintia W. Rivero, Jorge A. Trelles
Publikováno v:
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
Bioorganic & Medicinal Chemistry Letters
Universidad Nacional de La Plata
instacron:UNLP
Bioorganic & Medicinal Chemistry Letters
Graphical abstract
This work describes the application of thermophilic microorganisms for obtaining 6-halogenated purine nucleosides. Biosynthesis of 6-chloropurine-2′-deoxyriboside and 6-chloropurine riboside was achieved by Geobacillus stear
This work describes the application of thermophilic microorganisms for obtaining 6-halogenated purine nucleosides. Biosynthesis of 6-chloropurine-2′-deoxyriboside and 6-chloropurine riboside was achieved by Geobacillus stear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e99a2157624a4aae8b45773a5fa67c37
http://sedici.unlp.edu.ar/handle/10915/128236
http://sedici.unlp.edu.ar/handle/10915/128236