Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Eliana Barriocanal‐Casado"'
Autor:
Pilar González-García, María Elena Díaz-Casado, Agustín Hidalgo-Gutiérrez, Laura Jiménez-Sánchez, Mohammed Bakkali, Eliana Barriocanal-Casado, Germaine Escames, Riccardo Zenezini Chiozzi, Franziska Völlmy, Esther A. Zaal, Celia R. Berkers, Albert J.R. Heck, Luis C. López
Publikováno v:
Redox Biology, Vol 55, Iss , Pp 102403- (2022)
Defects in Coenzyme Q (CoQ) metabolism have been associated with primary mitochondrial disorders, neurodegenerative diseases and metabolic conditions. The consequences of CoQ deficiency have not been fully addressed, and effective treatment remains c
Externí odkaz:
https://doaj.org/article/a2808f9af5f749cfa28f555ecb1b8d8d
Autor:
Eliana Barriocanal-Casado, Agustín Hidalgo-Gutiérrez, Nuno Raimundo, Pilar González-García, Darío Acuña-Castroviejo, Germaine Escames, Luis C. López
Publikováno v:
EBioMedicine, Vol 42, Iss , Pp 511-523 (2019)
Background: The vast majority of mitochondrial disorders have limited the clinical management to palliative care. Rapamycin has emerged as a potential therapeutic drug for mitochondrial diseases since it has shown therapeutic benefits in a few mouse
Externí odkaz:
https://doaj.org/article/07065bcff0254f3b931335575664d3fe
Autor:
Agustín Hidalgo‐Gutiérrez, Eliana Barriocanal‐Casado, Mohammed Bakkali, M Elena Díaz‐Casado, Laura Sánchez‐Maldonado, Miguel Romero, Ramy K Sayed, Cornelia Prehn, Germaine Escames, Juan Duarte, Darío Acuña‐Castroviejo, Luis C López
Publikováno v:
EMBO Molecular Medicine, Vol 11, Iss 1, Pp 1-18 (2018)
Abstract Coenzyme Q (CoQ) deficiency has been associated with primary defects in the CoQ biosynthetic pathway or to secondary events. In some cases, the exogenous CoQ supplementation has limited efficacy. In the Coq9R239X mouse model with fatal mitoc
Externí odkaz:
https://doaj.org/article/9013018b61324fb0803832ef7595dea9
Autor:
Agustín Hidalgo-Gutiérrez, Eliana Barriocanal-Casado, María Elena Díaz-Casado, Pilar González-García, Riccardo Zenezini Chiozzi, Darío Acuña-Castroviejo, Luis Carlos López
Publikováno v:
Biomedicines, Vol 9, Iss 10, p 1457 (2021)
Primary mitochondrial diseases are caused by mutations in mitochondrial or nuclear genes, leading to the abnormal function of specific mitochondrial pathways. Mitochondrial dysfunction is also a secondary event in more common pathophysiological condi
Externí odkaz:
https://doaj.org/article/29411af8ce9c4e47b9a63df8169739f7
Autor:
Pilar González-García, Eliana Barriocanal-Casado, María Elena Díaz-Casado, Sergio López-Herrador, Agustín Hidalgo-Gutiérrez, Luis C. López
Publikováno v:
Antioxidants, Vol 10, Iss 11, p 1687 (2021)
Coenzyme Q (CoQ) is a vital lipophilic molecule that is endogenously synthesized in the mitochondria of each cell. The CoQ biosynthetic pathway is complex and not completely characterized, and it involves at least thirteen catalytic and regulatory pr
Externí odkaz:
https://doaj.org/article/a1125c1a52ef4f1eb8439aceaba38194
Autor:
Agustín Hidalgo-Gutiérrez, Pilar González-García, María Elena Díaz-Casado, Eliana Barriocanal-Casado, Sergio López-Herrador, Catarina M. Quinzii, Luis C. López
Publikováno v:
Antioxidants, Vol 10, Iss 4, p 520 (2021)
Coenzyme Q10 (CoQ10) is classically viewed as an important endogenous antioxidant and key component of the mitochondrial respiratory chain. For this second function, CoQ molecules seem to be dynamically segmented in a pool attached and engulfed by th
Externí odkaz:
https://doaj.org/article/d2f2d7c4ceb944a5aeba191f41b9ec50
Autor:
Marta Luna‐Sánchez, Agustín Hidalgo‐Gutiérrez, Tatjana M Hildebrandt, Julio Chaves‐Serrano, Eliana Barriocanal‐Casado, Ángela Santos‐Fandila, Miguel Romero, Ramy KA Sayed, Juan Duarte, Holger Prokisch, Markus Schuelke, Felix Distelmaier, Germaine Escames, Darío Acuña‐Castroviejo, Luis C López
Publikováno v:
EMBO Molecular Medicine, Vol 9, Iss 1, Pp 78-95 (2016)
Abstract Coenzyme Q (CoQ) is a key component of the mitochondrial respiratory chain, but it also has several other functions in the cellular metabolism. One of them is to function as an electron carrier in the reaction catalyzed by sulfide:quinone ox
Externí odkaz:
https://doaj.org/article/cfc05c1d2c8d4810a7dc5eb296a00eff
Autor:
Ana López, Francisco Ortiz, Carolina Doerrier, Carmen Venegas, Marisol Fernández-Ortiz, Paula Aranda, María E Díaz-Casado, Beatriz Fernández-Gil, Eliana Barriocanal-Casado, Germaine Escames, Luis C López, Darío Acuña-Castroviejo
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183090 (2017)
MPTP-mouse model constitutes a well-known model of neuroinflammation and mitochondrial failure occurring in Parkinson's disease (PD). Although it has been extensively reported that nitric oxide (NO●) plays a key role in the pathogenesis of PD, the
Externí odkaz:
https://doaj.org/article/b1b2b621e3034003ad635b07d645433a
Autor:
Eliana Barriocanal-Casado, Cristina Cueto-Ureña, Karim Benabdellah, Alejandra Gutiérrez-Guerrero, Marién Cobo, Agustín Hidalgo-Gutiérrez, Juan José Rodríguez-Sevilla, Francisco Martín, Luis C López
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0158344 (2016)
Recent clinical trials have shown that in vivo and ex vivo gene therapy strategies can be an option for the treatment of several neurological disorders. Both strategies require efficient and safe vectors to 1) deliver the therapeutic gene directly in
Externí odkaz:
https://doaj.org/article/bf2b493fbe1f46f4be69e7d4d6eeb7f7
Autor:
Alba Pesini, Giacomo Monzio-Compagnoni, Eliana Barriocanal-Casado, Agustin Hidalgo-Gutierrez, Giulio Kleiner, Giussepe A. Yanez, Mohamed Bakkali, Edoardo Monfrini, Yashpal S. Chhonker, Saba Tadesse, Delfina Larrea, Daryl J. Murry, Caterina Mariotti, Barbara Castellotti, Luis Lopez, Alesio Di Fonzo, Estela Area-Gomez, Catarina M. Quinzii
Publikováno v:
Thursday, April 27.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7063df5b865534b1f0ae43b9146d2d90
https://doi.org/10.1212/wnl.0000000000203767
https://doi.org/10.1212/wnl.0000000000203767