Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Eliana, Mariño"'
Autor:
Valerie Vandenbempt, Sema Elif Eski, Manoja K. Brahma, Ao Li, Javier Negueruela, Ylke Bruggeman, Stéphane Demine, Peng Xiao, Alessandra K. Cardozo, Nicolas Baeyens, Luciano G. Martelotto, Sumeet Pal Singh, Eliana Mariño, Conny Gysemans, Esteban N. Gurzov
Publikováno v:
iScience, Vol 27, Iss 1, Pp 108694- (2024)
Summary: An altered gut microbiota is associated with type 1 diabetes (T1D), affecting the production of short-chain fatty acids (SCFA) and glucose homeostasis. We previously demonstrated that enhancing serum acetate and butyrate using a dietary supp
Externí odkaz:
https://doaj.org/article/5023158edf454661a1c63b4ee36c62b7
Autor:
Kirstine J. Bell, Sonia Saad, Bree J. Tillett, Helen M. McGuire, Sara Bordbar, Yu Anne Yap, Long T. Nguyen, Marc R. Wilkins, Susan Corley, Shannon Brodie, Sussan Duong, Courtney J. Wright, Stephen Twigg, Barbara Fazekas de St Groth, Leonard C. Harrison, Charles R. Mackay, Esteban N. Gurzov, Emma E. Hamilton-Williams, Eliana Mariño
Publikováno v:
Microbiome, Vol 10, Iss 1, Pp 1-21 (2022)
Abstract Background Short-chain fatty acids (SCFAs) produced by the gut microbiota have beneficial anti-inflammatory and gut homeostasis effects and prevent type 1 diabetes (T1D) in mice. Reduced SCFA production indicates a loss of beneficial bacteri
Externí odkaz:
https://doaj.org/article/e25eb74805594ff78c91c45cb9747d55
Autor:
Signe Schultz Pedersen, Michala Prause, Christina Sørensen, Joachim Størling, Thomas Moritz, Eliana Mariño, Nils Billestrup
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4533 (2023)
Butyrate produced by the gut microbiota has beneficial effects on metabolism and inflammation. Butyrate-producing bacteria are supported by diets with a high fiber content, such as high-amylose maize starch (HAMS). We investigated the effects of HAMS
Externí odkaz:
https://doaj.org/article/7415f26618174b6f97fea38509fef945
Autor:
Mingjing Hu, David Eviston, Peter Hsu, Eliana Mariño, Ann Chidgey, Brigitte Santner-Nanan, Kahlia Wong, James L. Richards, Yu Anne Yap, Fiona Collier, Ann Quinton, Steven Joung, Michael Peek, Ron Benzie, Laurence Macia, David Wilson, Ann-Louise Ponsonby, Mimi L. K. Tang, Martin O’Hely, Norelle L. Daly, Charles R. Mackay, Jane E. Dahlstrom, The BIS Investigator Group, Peter Vuillermin, Ralph Nanan
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Maternal immunological dysregulation might affect the immunological development of the fetus. Here the authors show that decreased maternal acetate is associated with preeclampsia, impaired fetal thymic output and regulatory T cell development.
Externí odkaz:
https://doaj.org/article/c9a435d8124048e595fe54577e177533
Publikováno v:
Antioxidants, Vol 11, Iss 4, p 632 (2022)
Geraniin, an ellagitannin, has ameliorative properties against high-fat diet (HFD)-induced metabolic syndrome. Since geraniin has poor bioavailability, we hypothesised the interaction of this compound with gut microbiota as the main mechanism for imp
Externí odkaz:
https://doaj.org/article/62518620269e457e80dfbf4967ace869
Autor:
Abhirup Jayasimhan, Eliana Mariño
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Microbial metabolites have a profound effect on the development of type 1 diabetes (T1D). The cross-talk between the gut microbiota, the nervous system, and immune system is necessary to establish and maintain immune and gut tolerance. As quoted by H
Externí odkaz:
https://doaj.org/article/c08efd00c70d46f28e00418e4b6d3e58
Autor:
Yu Anne Yap, Eliana Mariño
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The rising global incidence of autoimmune and inflammatory conditions can be attributed to changes in the large portion of the immune system that belongs to our gastrointestinal tract (GI). The intestinal immune system serves as a gatekeeper to preve
Externí odkaz:
https://doaj.org/article/aeedf83959a7428bbe3629f98b6bd0d6
Publikováno v:
Bio-Protocol, Vol 8, Iss 1 (2018)
Alterations in diet and gut microbial ecology underlie the pathogenesis of type 1 diabetes (T1D). In the non-obese diabetic (NOD) mouse, we found high concentrations of bacterial metabolites acetate and butyrate in blood and faeces correlated with pr
Externí odkaz:
https://doaj.org/article/b14fb09a320d418f8e85f26730f5f8be
Autor:
Juliana Echevarria-Lima, Leandro Araujo Lobo, Charles R. Mackay, Dario S. Zamboni, Robson Coutinho-Silva, Ana Carolina Oliveira, Julio Scharfstein, Regina Maria Cavalcanti Pilotto Domingues, Aline Cristina Abreu Moreira-Souza, Eliana Mariño, Erivan Schnaider Ramos-Junior, Maria Bellio, Eliane de Oliveira Ferreira, Juliana P Castelpoggi, Bruno Jennings-Almeida
Publikováno v:
The Journal of Immunology. 206:2441-2452
Intestinal barrier is essential for dietary products and microbiota compartmentalization and therefore gut homeostasis. When this barrier is broken, cecal content overflows into the peritoneal cavity, leading to local and systemic robust inflammatory
Autor:
Artiene Tatian, Sara Bordbar, Samuel Der Sarkissian, Jane A. Woods, Geoffrey D. Cains, Chun Wie Chong, Eliana Mariño, John W. Frew
Publikováno v:
Experimental dermatologyREFERENCES. 31(12)
Altered gut microbiota composition has been observed in individuals with hidradenitis suppurutiva (HS) and many other inflammatory diseases, including obesity, type 1 and type 2 diabetes. Here, we addressed whether adalimumab, a systemic anti-inflamm