Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Elia J Duh"'
Publikováno v:
PLoS Biology, Vol 19, Iss 12, p e3001510 (2021)
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infects a broader range of mammalian species than previously predicted, binding a diversity of angiotensin converting enzyme 2 (ACE2) orthologs despite extensive sequence divergence. Within
Externí odkaz:
https://doaj.org/article/ef2cd11c4f3441b2be1b8c76cc620b93
Autor:
Lingli Zhou, Zhenhua Xu, Haining Lu, Hongkwan Cho, Yangyiran Xie, Grace Lee, Kaoru Ri, Elia J. Duh
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-16 (2024)
Abstract Ischemic retinopathies including diabetic retinopathy are major causes of vision loss. Inner blood-retinal barrier (BRB) breakdown with retinal vascular hyperpermeability results in macular edema. Although dysfunction of the neurovascular un
Externí odkaz:
https://doaj.org/article/8cb0084117dc4cfc9d87846b0b1230c0
Autor:
M. Elizabeth Hartnett, MD, Ward Fickweiler, MD, PhD, Anthony P. Adamis, MD, Michael Brownlee, MD, Arup Das, MD, PhD, Elia J. Duh, MD, Edward P. Feener, PhD, George King, MD, Renu Kowluru, PhD, Ulrich F.O. Luhmann, PhD, Federica Storti, PhD, Charles C. Wykoff, MD, PhD, Lloyd Paul Aiello, MD, PhD
Publikováno v:
Ophthalmology Science, Vol 4, Iss 5, Pp 100521- (2024)
Purpose: Hyperglycemia is a major risk factor for early lesions of diabetic retinal disease (DRD). Updating the DRD staging system to incorporate relevant basic and cellular mechanisms pertinent to DRD is necessary to better address early disease, di
Externí odkaz:
https://doaj.org/article/d168a05b499a4366a82cce9f5b9f8421
Autor:
Tien-En Tan, MBBS (Hons), FRCOphth, Lee M. Jampol, MD, Frederick L. Ferris, MD, Ramin Tadayoni, MD, PhD, Srinivas R. Sadda, MD, Victor Chong, MD, FRCOphth, Amitha Domalpally, MD, PhD, Barbara L. Blodi, MD, Elia J. Duh, MD, Christine A. Curcio, PhD, David A. Antonetti, PhD, Sanjoy Dutta, PhD, S. Robert Levine, MD, Jennifer K. Sun, MD, MPH, Thomas W. Gardner, MD, MS, Tien Yin Wong, MD, PhD
Publikováno v:
Ophthalmology Science, Vol 4, Iss 3, Pp 100449- (2024)
Purpose: To review the evidence for imaging modalities in assessing the vascular component of diabetic retinal disease (DRD), to inform updates to the DRD staging system. Design: Standardized narrative review of the literature by an international exp
Externí odkaz:
https://doaj.org/article/bbd3d6852c8f4fc5a8e43e9cf46b6999
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature Communications
Birds (Aves) display high metabolic rates and oxygen consumption relative to mammals, increasing reactive oxygen species (ROS) formation. Although excess ROS reduces lifespan by causing extensive cellular dysfunction and damage, birds are remarkably
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71bb8dfdc9ad065f034b31532fb48be8
http://link.springer.com/article/10.1038/s41467-020-16129-4
http://link.springer.com/article/10.1038/s41467-020-16129-4
Autor:
Sheldon Rowan, Shuhong Jiang, Sarah G. Francisco, Laura C. D. Pomatto, Zhiwei Ma, Xiaodong Jiao, Maria M. Campos, Sandeep Aryal, Shaili D. Patel, Binapani Mahaling, S. Amer Riazuddin, Elia J. Duh, Salil A. Lachke, J. Fielding Hejtmancik, Rafael de Cabo, Paul G. FitzGerald, Allen Taylor
Publikováno v:
Investigative ophthalmology & visual science, vol 62, iss 15
Investigative Ophthalmology & Visual Science
Investigative Ophthalmology & Visual Science
Purpose Age-related cataracts affect the majority of older adults and are a leading cause of blindness worldwide. Treatments that delay cataract onset or severity have the potential to delay cataract surgery, but require relevant animal models that r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bfc6180f7e42f5e7785cd513a215d47
https://escholarship.org/uc/item/3d327405
https://escholarship.org/uc/item/3d327405
Autor:
Evan M. Bloch, Yu Jui Kung, John H. Lin, Tzyy Choou Wu, Liangmei He, Ya Chea Tsai, Ssu-Hsueh Tseng, Chien Fu Hung, Brandon Lam, Elia J. Duh, Gianni M Castiglione, Aaron M. Milstone, Aaron A.R. Tobian, Richard B. S. Roden, Emily R Egbert
Publikováno v:
Cell Reports, Vol 37, Iss 3, Pp 109838-(2021)
Cell Reports
Cell Reports
As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spreads, variants with enhanced virulence and transmissibility have emerged. Although in vitro systems allow rapid characterization, they do not fully recapitulate the dynamic interactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::064829e7b9b5615be78288f1820de70f
http://www.sciencedirect.com/science/article/pii/S2211124721013024
http://www.sciencedirect.com/science/article/pii/S2211124721013024
Autor:
Hongkwan Cho, Yangyiran Xie, Lingli Zhou, Elia J. Duh, Grace P. Lee, Qiaoyan Hui, Siva P. Kambhampati, Rangaramanujam M. Kannan, Michael J. Lai
Publikováno v:
Adv Ther (Weinh)
Diabetic retinopathy (DR) is the leading cause of blindness in working-age adults. Severe visual loss in DR is primarily due to proliferative diabetic retinopathy, characterized by pathologic preretinal angiogenesis driven by retinal ischemia. Microg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e004e3e2337437640c5eb721998c1493
https://pubmed.ncbi.nlm.nih.gov/34527806
https://pubmed.ncbi.nlm.nih.gov/34527806
Expression of the SARS-CoV-2 Receptor ACE2 in Human Retina and Diabetes—Implications for Retinopathy
Autor:
Lingli Zhou, James Guerra, Elia J. Duh, Paride Fenaroli, Avi Z. Rosenberg, Zhenhua Xu, Charles G. Eberhart
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose: To investigate the expression of angiotensin-converting enzyme 2 (ACE2), the receptor for SARS-CoV-2 in human retina. Methods: Human post-mortem eyes from 13 non-diabetic control cases and 11 diabetic retinopathy cases were analyzed for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e8f88e085edf329b274fa38aa510f79
http://europepmc.org/articles/PMC8185397
http://europepmc.org/articles/PMC8185397
Autor:
Elia J. Duh, Qingguo Xu, Jin Yang, Tuo Meng, Yumin Oh, Yoo Chun Kim, Shiyu Xia, Matthew J. Hartsock, Jennifer E. Thorne, Charles G. Eberhart, Justin Hanes, Laura M. Ensign, Zheng Ding, Walter J. Stark, Lixia Luo
Publikováno v:
Journal of Controlled Release. 296:68-80
Noninfectious uveitis is a potentially blinding ocular condition that often requires treatment with corticosteroids to prevent inflammation-related ocular complications. Severe forms of uveitis such as panuveitis that affects the whole eye often requ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::760604b18948df02beca894c3b5eef82
https://doi.org/10.1016/j.jconrel.2019.01.018
https://doi.org/10.1016/j.jconrel.2019.01.018