Výsledky vyhledávání - "Elia Brodsky"

Akademický článek

Global Analysis of Plasmodium falciparum Dihydropteroate Synthase Variants Associated with Sulfadoxine Resistance Reveals Variant Distribution and Mechanisms of Resistance: A Computational-Based Study

Autor: Rita Afriyie Boateng, James L. Myers-Hansen, Nigel N. O. Dolling, Benedicta A. Mensah, Elia Brodsky, Mohit Mazumder, Anita Ghansah

Publikováno v: Molecules, Vol 28, Iss 1, p 145 (2022)

The continual rise in sulfadoxine (SDX) resistance affects the therapeutic efficacy of sulfadoxine-pyrimethamine; therefore, careful monitoring will help guide its prolonged usage. Mutations in Plasmodium falciparum dihydropteroate synthase (Pfdhps)

Externí odkaz: https://doaj.org/article/261f3684324c4a75a9416ec774f113ab

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Akademický článek

Comparative Genomics Analysis of Repetitive Elements in Ten Gymnosperm Species: 'Dark Repeatome' and Its Abundance in Conifer and Gnetum Species

Autor: Avi Titievsky, Yuliya A. Putintseva, Elizaveta A. Taranenko, Sofya Baskin, Natalia V. Oreshkova, Elia Brodsky, Alexandra V. Sharova, Vadim V. Sharov, Julia Panov, Dmitry A. Kuzmin, Leonid Brodsky, Konstantin V. Krutovsky

Publikováno v: Life, Vol 11, Iss 11, p 1234 (2021)

Repetitive elements (RE) and transposons (TE) can comprise up to 80% of some plant genomes and may be essential for regulating their evolution and adaptation. The “repeatome” information is often unavailable in assembled genomes because genomic a

Externí odkaz: https://doaj.org/article/405290e96a494cba8566672ffe00de22

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Global Analysis of

Autor: Rita Afriyie, Boateng, James L, Myers-Hansen, Nigel N O, Dolling, Benedicta A, Mensah, Elia, Brodsky, Mohit, Mazumder, Anita, Ghansah

Publikováno v: Molecules (Basel, Switzerland). 28(1)

The continual rise in sulfadoxine (SDX) resistance affects the therapeutic efficacy of sulfadoxine-pyrimethamine; therefore, careful monitoring will help guide its prolonged usage. Mutations in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ea331fb85b3c491d43036c8268e8d5ab
https://pubmed.ncbi.nlm.nih.gov/36615340

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Transcriptomic analysis of DNA damage response in zebrafish embryos under simulated microgravity

Autor: Subhrajit Barua, Aleksey Komissarov, Harpreet Kaur, Elia Brodsky

ObjectiveThe objective of this study is to study the transcriptome of zebrafish embryos subjected to simulated microgravity and explore affected biological pathways, especially DNA damage response (DDR). The research question is whether simulated mic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::440d33acdcb44df56ed4b7d073e9cd20
https://doi.org/10.1101/2021.09.30.462627

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Analysis of gene expression profiles to study malaria vaccine dose efficacy and immune response modulation

Autor: Supantha Dey, Harpreet Kaur, Mohit Mazumder, Elia Brodsky

Publikováno v: Genomics & Informatics. 20:e32

Malaria is a life-threatening disease, and Africa is still one of the most affected endemic regions despite years of policy to limit infection and transmission rates. Further, studies into the variable efficacy of the vaccine are needed to provide a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::127af04d9d35f9ab28d825c833df0399
https://doi.org/10.5808/gi.22049

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In silico Analysis of Transcriptomic Profiling and Affected Biological pathways in Multiple Sclerosis

Autor: Elia Brodsky, Harpreet Kaur, Rutvi D Vaja, Mohit Mazumder

Multiple sclerosis (MS) is a chronic autoimmune, inflammatory neurological disease that is widely associated with Grey and white matter degradation due to the demyelination of axons. Thus exposing the underlying causes of this condition can lead to a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6d3826c7ea7d3198cf218b749b608ed9
https://doi.org/10.1101/2021.08.15.456398

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Analysis of Gene Expression Profiles to study Malaria Vaccine Dose Efficacy & Immune Response Modulation

Autor: Harpreet Kaur, S. Dey, Mohit Mazumder, Elia Brodsky

Malaria is a life-threatening disease, and the Africa is still one of the most affected endemic regions despite years of policy to limit infection and transmission rates. Further, studies into the variable efficacy of the vaccine are needed to provid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0e960e3c4e765000f61956be46e95254
https://doi.org/10.1101/2021.08.05.454986

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A defective viral genome strategy elicits broad protective immunity against respiratory viruses

Publikováno v: Cell, vol 184, iss 25

Summary RNA viruses generate defective viral genomes (DVG) that can interfere with replication of the parental wild-type virus. To examine their therapeutic potential, we created a DVG by deleting the capsid-coding region of poliovirus. Strikingly, i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10580689b8609c812f9c903a99feb401
https://pubmed.ncbi.nlm.nih.gov/35590140

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In Silico Analysis and Characterization of Differentially Expressed Genes to Distinguish Glioma Stem Cells from Normal Neural Stem Cells

Autor: Urja Parekh, Mohit Mazumder, Elia Brodsky, Harpreet Kaur

Glioblastoma multiforme (GBM) is a heterogeneous, invasive primary brain tumor that develops chemoresistance post therapy. Theories regarding the aetiology of GBM focus on transformation of normal neural stem cells (NSCs) to a cancerous phenotype or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a67e673d8f53f56248d8b28f63b54933
https://doi.org/10.1101/2021.04.05.438487

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