A fluorescent perilipin 2 knock-in mouse model reveals a high abundance of lipid droplets in the developing and adult brain

Autor: Sofia Madsen, Ana C. Delgado, Christelle Cadilhac, Vanille Maillard, Fabrice Battiston, Carla Marie Igelbüscher, Simon De Neck, Elia Magrinelli, Denis Jabaudon, Ludovic Telley, Fiona Doetsch, Marlen Knobloch

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)

Abstract Lipid droplets (LDs) are dynamic lipid storage organelles. They are tightly linked to metabolism and can exert protective functions, making them important players in health and disease. Most LD studies in vivo rely on staining methods, provi

Externí odkaz: https://doaj.org/article/ff4e8e685b804c22b99533daadebdf61

Pum2 and TDP-43 refine area-specific cytoarchitecture post-mitotically and modulate translation of Sox5, Bcl11b, and Rorb mRNAs in developing mouse neocortex

Autor: Kawssar Harb, Melanie Richter, Nagammal Neelagandan, Elia Magrinelli, Hend Harfoush, Katrin Kuechler, Melad Henis, Irm Hermanns-Borgmeyer, Froylan Calderon de Anda, Kent Duncan

Publikováno v: eLife, Vol 11 (2022)

In the neocortex, functionally distinct areas process specific types of information. Area identity is established by morphogens and transcriptional master regulators, but downstream mechanisms driving area-specific neuronal specification remain uncle

Externí odkaz: https://doaj.org/article/52d7db56e86447c3bcf8bfe8b80e5c2d

A fluorescent perilipin 2 knock-in mouse model visualizes lipid droplets in the developing and adult brain

Autor: Sofia Madsen, Ana C. Delgado, Christelle Cadilhac, Fabrice Battison, Vanille Maillard, Elia Magrinelli, Denis Jabaudon, Ludovic Telley, Fiona Doetsch, Marlen Knobloch

Lipid droplets (LDs) are dynamic lipid storage organelles. They are tightly linked to metabolism and can exert protective functions, making them important players in health and disease. Most LD studies in vivo rely on staining methods, providing only

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8782e9daa5925279582d8feadaedb3c2
https://edoc.unibas.ch/91765/

Heterogeneous Fates of Simultaneously-Born Neurons During Early Corticogenesis

Autor: Esther Klingler, Camilla Bellone, Denis Jabaudon, Elia Magrinelli, Christelle Glangetas, Robin Jan Wagener, Natalia Baumann

Neocortical excitatory neurons belong to diverse cell types, which can be distinguished by their dates of birth, laminar location, connectivity and molecular identities. During embryogenesis, apical progenitors (APs) located in the ventricular zone f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::072c20b0811ed71ee36ae28b1468f474
https://doi.org/10.21203/rs.3.rs-956593/v1

COUP-TFI/Nr2f1 Orchestrates Intrinsic Neuronal Activity during Development of the Somatosensory Cortex

Autor: Christian Alfano, Andreas Frick, Chiara Tocco, Xavier Leinekugel, Andrea Marcantoni, Michèle Studer, Elia Magrinelli, Celeste Ferraguto, Giulia Tomagra, Michele Bertacchi, Isabel del Pino

Publikováno v: Cerebral Cortex
Cerebral Cortex, Oxford University Press (OUP), 2020, ⟨10.1093/cercor/bhaa137⟩
CEREBRAL CORTEX
r-CIPF: Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
Centro de Investigación Principe Felipe (CIPF)
r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
instname

The formation of functional cortical maps in the cerebral cortex results from a timely regulated interaction between intrinsic genetic mechanisms and electrical activity. To understand how transcriptional regulation influences network activity and ne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20ae759e75dfea365a848fb608da75dd
https://hal.archives-ouvertes.fr/hal-02903178