Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Eli Shobin"'
Autor:
Ilana Fogelman, Tim West, Joel B. Braunstein, Philip B. Verghese, Kristopher M. Kirmess, Matthew R. Meyer, John H. Contois, Eli Shobin, Kyle L. Ferber, Jake Gagnon, Carrie E. Rubel, Danielle Graham, Randall J. Bateman, David M. Holtzman, Shuguang Huang, Joanne Yu, Sha Yang, Kevin E. Yarasheski
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 10, Iss 5, Pp 765-778 (2023)
Abstract Background The amyloid probability score (APS) is the model read‐out of the analytically validated mass spectrometry‐based PrecivityAD® blood test that incorporates the plasma Aβ42/40 ratio, ApoE proteotype, and age to identify the lik
Externí odkaz:
https://doaj.org/article/93cd3d1753d44499bd17189a775abc36
Autor:
Tara L. Moore, Penny L. Shultz, Mark B. Moss, Samantha M. Calderazzo, Eli Shobin, Douglas L. Rosene, Ronald J. Killiany, Bethany G E Bowley
Publikováno v:
GeroScience. 39:571-584
Studies of both humans and non-human primates have demonstrated that aging is typically characterized by a decline in cognition that can occur as early as the fifth decade of life. Age-related changes in working memory are particularly evident and me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5148684968571498a1f3961ba2caa8f0
https://doi.org/10.1007/s11357-017-9998-2
https://doi.org/10.1007/s11357-017-9998-2
Autor:
Adrian L. Oblak, Douglas L. Rosene, Farzad Mortazavi, Brian C Kramer, Eli Shobin, Samantha M. Calderazzo, Tara L. Moore, Mary E. Orczykowski, Seth P. Finklestein, Monica A. Pessina
Publikováno v:
Brain Res
Cortical injury elicits long-term cytotoxic and cytoprotective mechanisms within the brain and the balance of these pathways can determine the functional outcome for the individual. Cytotoxicity is exacerbated by production of reactive oxygen species
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f3c964e1b98826d7b45bbc7e2741058
https://doi.org/10.1096/fasebj.2019.33.1_supplement.lb166
https://doi.org/10.1096/fasebj.2019.33.1_supplement.lb166
Autor:
Douglas L. Rosene, Ajay R Uprety, Penny L. Shultz, Samantha M. Calderazzo, Mark B. Moss, Bethany G E Bowley, Tara L. Moore, Eli Shobin
Publikováno v:
Somatosensorymotor research. 35(1)
Aged individuals experience decreased fine motor function of the hand and digits, which could result, in part, from the chronic, systemic state of inflammation that occurs with aging. Recent research for treating age-related inflammation has focused
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c7fd0e922c59dcfeb9b279d502d0947
https://pubmed.ncbi.nlm.nih.gov/29447046
https://pubmed.ncbi.nlm.nih.gov/29447046
Autor:
Samantha M. Calderazzo, Larissa I. Estrada, Nadine C. Heyworth, Douglas L. Rosene, Sherri A. Eldridge, Eli Shobin, Farzad Mortazavi, Tara L. Moore, Mary E. Orczykowski, Michael P. Bowley
While cognitive decline is observed in the normal aging monkey, neurons are not lost with age. Instead, frontal white matter is lost as myelin degenerates and both correlate with age-related cognitive decline. As age-related myelin damage increases,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a035e9d539dc8648ec4dec7cc310de38
https://europepmc.org/articles/PMC5411373/
https://europepmc.org/articles/PMC5411373/
Autor:
Eli Shobin, Samantha M. Calderazzo, Tara L. Moore, Mary E. Orczykowski, Brian C Kramer, Farzad Mortazavi, Douglas L. Rosene
Publikováno v:
Stroke. 48
Introduction: Stroke is the leading cause of long-term disability in the United States due to impairments that endure after brain injury. While studies in rodent models have evaluated numerous neurorestorative treatments following stroke, none have r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b71d691827afbd75dc009e3aa9b9007
https://doi.org/10.1161/str.48.suppl_1.wp112
https://doi.org/10.1161/str.48.suppl_1.wp112
Publikováno v:
Neuroscience. 227:10-21
The ventral pallidum (VP) is a major recipient of inhibitory projections from nucleus accumbens (Acb) neurons that differentially express the reward (enkephalin) and aversion (dynorphin)-associated opioid peptides. The cannabinoid-1 receptor (CB1R) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9996acf8e2b4d35eff6f1face779fd4
https://doi.org/10.1016/j.neuroscience.2012.07.050
https://doi.org/10.1016/j.neuroscience.2012.07.050
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 38(1)
Cannabinoid modulation of dopaminergic transmission is suggested by the ability of delta9-tetrahydrocanabinoid to affect motor and motivated behaviors in a manner similar to that produced by pharmacological manipulation of the nigrostriatal and mesoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d3572f8603e9039768807a8da8303eb
https://pubmed.ncbi.nlm.nih.gov/22265889
https://pubmed.ncbi.nlm.nih.gov/22265889