Zobrazeno 1 - 10
of 153
pro vyhledávání: '"Eli Eisenberg"'
Publikováno v:
Clinical and Translational Allergy, Vol 14, Iss 4, Pp n/a-n/a (2024)
Abstract Background The effect of the amount of transient cow's milk formula (CMF) consumed during the first days of life on IgE‐cow's milk allergy (IgE‐CMA) is unknown. Methods A cohort of 58 patients with IgE‐CMA was identified from a large s
Externí odkaz:
https://doaj.org/article/007c5581502c40bfb1f191de8dca64be
Autor:
Tram Anh Nguyen, Jia Wei Joel Heng, Yan Ting Ng, Rui Sun, Shira Fisher, Gokce Oguz, Pornchai Kaewsapsak, Shifeng Xue, Bruno Reversade, Adaikalavan Ramasamy, Eli Eisenberg, Meng How Tan
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-25 (2023)
Abstract Background Xenopus has served as a valuable model system for biomedical research over the past decades. Notably, ADAR was first detected in frog oocytes and embryos as an activity that unwinds RNA duplexes. However, the scope of A-to-I RNA e
Externí odkaz:
https://doaj.org/article/abccd887de8d46a085dc1ca76e7b252c
Autor:
Isabel C. Vallecillo-Viejo, Gjendine Voss, Caroline B. Albertin, Noa Liscovitch-Brauer, Eli Eisenberg, Joshua J. C. Rosenthal
Publikováno v:
Frontiers in Genome Editing, Vol 5 (2023)
The coleoid cephalopods display unusually extensive mRNA recoding by adenosine deamination, yet the underlying mechanisms are not well understood. Because the adenosine deaminases that act on RNA (ADAR) enzymes catalyze this form of RNA editing, the
Externí odkaz:
https://doaj.org/article/9e6f3930f21f458cbfb2c52a3327a7da
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 4, p e1010923 (2023)
Adenosine-to-inosine RNA editing is essential to prevent undesired immune activation. This diverse process alters the genetic content of the RNA and may recode proteins, change splice sites and miRNA targets, and mimic genomic mutations. Recent studi
Externí odkaz:
https://doaj.org/article/4fc29ed28e8a47918044fd39ea67cf26
Autor:
Adi Avram-Shperling, Eli Kopel, Itamar Twersky, Orshay Gabay, Amit Ben-David, Sarit Karako-Lampert, Joshua J C Rosenthal, Erez Y Levanon, Eli Eisenberg, Shay Ben-Aroya
Publikováno v:
PLoS Genetics, Vol 19, Iss 3, p e1010661 (2023)
The most abundant form of RNA editing in metazoa is the deamination of adenosines into inosines (A-to-I), catalyzed by ADAR enzymes. Inosines are read as guanosines by the translation machinery, and thus A-to-I may lead to protein recoding. The abili
Externí odkaz:
https://doaj.org/article/591564ca4c774ab6b01bc64e9f42b725
Autor:
Orshay Gabay, Yoav Shoshan, Eli Kopel, Udi Ben-Zvi, Tomer D. Mann, Noam Bressler, Roni Cohen‐Fultheim, Amos A. Schaffer, Shalom Hillel Roth, Ziv Tzur, Erez Y. Levanon, Eli Eisenberg
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Gabay et al. provide a highly-accurate atlas of recoding by A-to-I RNA editing in human, profiled across tissues and cell subpopulations. Most highly edited sites are evolutionary conserved in non-primate mammals, attesting for adaptation.
Externí odkaz:
https://doaj.org/article/9b0696ffc9df4cbd9cd96d999fdd2d5c
Autor:
Michal Barak, Hagit T. Porath, Gilad Finkelstein, Binyamin A. Knisbacher, Ilana Buchumenski, Shalom Hillel Roth, Erez Y. Levanon, Eli Eisenberg
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-10 (2020)
Abstract Background Mobile elements comprise a large fraction of metazoan genomes. Accumulation of mobile elements is bound to produce multiple putative double-stranded RNA (dsRNA) structures within the transcriptome. These endogenous dsRNA structure
Externí odkaz:
https://doaj.org/article/80a92672d7614a75a5805c2a67aea2a3
Autor:
Hagit T. Porath, Esther Hazan, Hagai Shpigler, Mira Cohen, Mark Band, Yehuda Ben-Shahar, Erez Y. Levanon, Eli Eisenberg, Guy Bloch
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Bumblebee workers are genetically highly similar but they show different behaviors such as brood care and foraging. Here the authors report a high level of ADAR-mediated RNA editing in the bumblebee Bombus terrestris and its weak correlation to task
Externí odkaz:
https://doaj.org/article/87a1442fe9154b3c97e80db85f7ebad6
Publikováno v:
iScience, Vol 24, Iss 1, Pp 101983- (2021)
Summary: Social insects exhibit extensive phenotypic diversities among the genetically similar individuals, suggesting a role for the epigenetic regulations beyond the genome level. The ADAR-mediated adenosine-to-inosine (A-to-I) RNA editing, an evol
Externí odkaz:
https://doaj.org/article/38c5679ee0fc42e58cf31215d5169320
Autor:
Claudio Lo Giudice, Domenico Alessandro Silvestris, Shalom Hillel Roth, Eli Eisenberg, Graziano Pesole, Angela Gallo, Ernesto Picardi
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Massive transcriptome sequencing through the RNAseq technology has enabled quantitative transcriptome-wide investigation of co-/post-transcriptional mechanisms such as alternative splicing and RNA editing. The latter is abundant in human transcriptom
Externí odkaz:
https://doaj.org/article/71f8fd4c17054856b761ea76504259c8