Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Elham Shahinfard"'
Autor:
Michele Matarazzo, Alexandra Pérez-Soriano, Nasim Vafai, Elham Shahinfard, Kevin Ju-Chieh Cheng, Jessamyn McKenzie, Nicole Neilson, Qing Miao, Paul Schaffer, Hitoshi Shinotoh, Jeffrey H. Kordower, Vesna Sossi, A. Jon Stoessl
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract Parkinson’s disease (PD) is associated with aggregation of misfolded α-synuclein and other proteins, including tau. We designed a cross-sectional study to quantify the brain binding of [11C]PBB3 (a ligand known to bind to misfolded tau an
Externí odkaz:
https://doaj.org/article/4c1e5ab38e104962a02dffa3537818be
Autor:
Julia G. Mannheim, Jessie Fanglu Fu, Tilman Wegener, Ivan S. Klyuzhin, Nasim Vafai, Elham Shahinfard, Jessamyn McKenzie, Audrey Strongosky, Zbigniew K. Wszolek, A. Jon Stoessl, Vesna Sossi
Publikováno v:
NeuroImage: Clinical, Vol 42, Iss , Pp 103600- (2024)
Several genetic pathogenic variants increase the risk of Parkinson’s disease (PD) with pathogenic variants in the leucine-rich repeat kinase 2 (LRRK2) gene being among the most common. A joint pattern analysis based on multi-set canonical correlati
Externí odkaz:
https://doaj.org/article/98a7c3ac0d274449bc932856a0d3b280
Autor:
Julia G. Mannheim, Ju-Chieh (Kevin) Cheng, Nasim Vafai, Elham Shahinfard, Carolyn English, Jessamyn McKenzie, Jing Zhang, Laura Barlow, Vesna Sossi
Publikováno v:
EJNMMI Physics, Vol 8, Iss 1, Pp 1-22 (2021)
Abstract Background The Siemens high-resolution research tomograph (HRRT - a dedicated brain PET scanner) is to this day one of the highest resolution PET scanners; thus, it can serve as useful benchmark when evaluating performance of newer scanners.
Externí odkaz:
https://doaj.org/article/15ff3c5172f1466f82e6f9aaa0addaf1
Autor:
Karteek Popuri, Mirza Faisal Beg, Hyunwoo Lee, Rakesh Balachandar, Lei Wang, Vesna Sossi, Claudia Jacova, Matt Baker, Elham Shahinfard, Rosa Rademakers, Ian R.A. Mackenzie, Ging-Yuek R. Hsiung
Publikováno v:
NeuroImage: Clinical, Vol 31, Iss , Pp 102687- (2021)
Objective: Our aim is to investigate patterns of brain glucose metabolism using fluorodeoxyglucose positron emission tomography (FDG-PET) in presymptomatic carriers of the C9orf72 repeat expansion to better understand the early preclinical stages of
Externí odkaz:
https://doaj.org/article/4e068226b77a4abea6cd627065276f3b
Autor:
Jessie Fanglu Fu, Ivan Klyuzhin, Shuying Liu, Elham Shahinfard, Nasim Vafai, Jessamyn McKenzie, Nicole Neilson, Rostom Mabrouk, Matthew A. Sacheli, Daryl Wile, Martin J. McKeown, A. Jon Stoessl, Vesna Sossi
Publikováno v:
NeuroImage: Clinical, Vol 19, Iss , Pp 652-660 (2018)
We used positron emission tomography imaging with [11C]-3-amino-4-(2-dimethylaminomethylphenylsulfanyl)- benzonitrile (DASB) and principal component analysis to investigate whether a specific Parkinson's disease (PD)-related spatial covariance patter
Externí odkaz:
https://doaj.org/article/b77d6cabc39b4feda0e61bdc31b70a56
Autor:
Jessie Fanglu Fu, Ivan Klyuzhin, Jessamyn McKenzie, Nicole Neilson, Elham Shahinfard, Katie Dinelle, Martin J. McKeown, A. Jon Stoessl, Vesna Sossi
Publikováno v:
NeuroImage: Clinical, Vol 23, Iss , Pp - (2019)
Most neurodegenerative diseases are known to affect several aspects of brain function, including neurotransmitter systems, metabolic and functional connectivity. Diseases are generally characterized by common clinical characteristics across subjects,
Externí odkaz:
https://doaj.org/article/d91f2f3656444c4cb40224625c46c22d
Autor:
Alexander D Wright, Michael Jarrett, Irene Vavasour, Elham Shahinfard, Shannon Kolind, Paul van Donkelaar, Jack Taunton, David Li, Alexander Rauscher
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0150215 (2016)
Impact-related mild traumatic brain injuries (mTBI) are a major public health concern, and remain as one of the most poorly understood injuries in the field of neuroscience. Currently, the diagnosis and management of such injuries are based largely o
Externí odkaz:
https://doaj.org/article/1329507603ea49249a20ebbb921221c6
Autor:
Adam George White, Ariana Cahn, Gayatri Saraf, Elham Shahinfard, Lakshmi N. Yatham, Jairo Vinícius Pinto, Vesna Sossi, Nasim Vafai
Publikováno v:
Journal of Affective Disorders. 295:724-732
Background Neurochemical mechanisms underlying stress induced relapse of mood episodes in Bipolar I Disorder (BD) remain unknown. This study investigated whether euthymic BD patients have a greater dopamine release in ventral striatum, caudate and pu
Autor:
Jing Zhang, Nasim Vafai, Vesna Sossi, Ju-Chieh Kevin Cheng, Carolyn English, Elham Shahinfard, Laura Barlow, Julia G. Mannheim, Jessamyn McKenzie
Publikováno v:
EJNMMI Physics, Vol 8, Iss 1, Pp 1-22 (2021)
EJNMMI Physics
EJNMMI Physics
Background The Siemens high-resolution research tomograph (HRRT - a dedicated brain PET scanner) is to this day one of the highest resolution PET scanners; thus, it can serve as useful benchmark when evaluating performance of newer scanners. Here, we
Autor:
Hyunwoo Lee, Vanessa Wiggermann, Alexander Rauscher, Christian Kames, Mirza Faisal Beg, Karteek Popuri, Roger Tam, Kevin Lam, Claudia Jacova, Elham Shahinfard, Vesna Sossi, Jacqueline A. Pettersen, Ging-Yuek Robin Hsiung
Publikováno v:
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques.
Background: A large proportion of Alzheimer’s disease (AD) patients have coexisting subcortical vascular dementia (SVaD), a condition referred to as mixed dementia (MixD). Brain imaging features of MixD presumably include those of cerebrovascular d