Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Elhadj Djeriou"'
Autor:
Adama Gansane, Moussa Lingani, Adoke Yeka, Alain Nahum, Marielle Bouyou-Akotet, Ghyslain Mombo-Ngoma, Grace Kaguthi, Catalina Barceló, Bart Laurijssens, Cathy Cantalloube, Fiona Macintyre, Elhadj Djeriou, Andreas Jessel, Raphaël Bejuit, Helen Demarest, Anne Claire Marrast, Siaka Debe, Halidou Tinto, Afizi Kibuuka, Diolinda Nahum, Denise Patricia Mawili-Mboumba, Rella Zoleko-Manego, Irene Mugenya, Frederick Olewe, Stephan Duparc, Bernhards Ogutu
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-16 (2023)
Abstract Background The contribution of artefenomel to the clinical and parasiticidal activity of ferroquine and artefenomel in combination in uncomplicated Plasmodium falciparum malaria was investigated. Methods This Phase 2a, randomized, open-label
Externí odkaz:
https://doaj.org/article/f65785a4b7b84297a418e877222c7d6a
Autor:
Jana Held, Christian Supan, Carmen L. Ospina Salazar, Halidou Tinto, Léa Nadège Bonkian, Alain Nahum, Ali Sié, Salim Abdulla, Cathy Cantalloube, Elhadj Djeriou, Marielle Bouyou-Akotet, Bernhards Ogutu, Benjamin Mordmüller, Andrea Kreidenweiss, Mohamadou Siribie, Sodiomon B. Sirima, Peter G. Kremsner
Publikováno v:
Malaria Journal, Vol 16, Iss 1, Pp 1-12 (2017)
Abstract Background Malaria remains one of the most important infectious diseases. Treatment options for severe malaria are limited and the choline analogue SAR97276A is a novel chemical entity that was developed primarily as treatment for severe mal
Externí odkaz:
https://doaj.org/article/ef1036a672254739b5714c7719ed185b
Autor:
Samantha Akakpo, James S. McCarthy, Elhadj Djeriou, Katalin Csermak-Renner, G. Dennis Shanks, Didier Leboulleux, Anand Odedra, Cornelis Winnips, Mohamed Farouk Chughlay, Aditya H. Gaur, Stephan Chalon
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 103:378-393
Malaria volunteer infection studies (VISs) accelerate new drug and vaccine development. In the induced blood-stage malaria (IBSM) model, volunteers are inoculated with erythrocytes infected with Plasmodium falciparum. Observations of elevated liver e
Autor:
Mohamed Farouk, Chughlay, Samantha, Akakpo, Anand, Odedra, Katalin, Csermak-Renner, Elhadj, Djeriou, Cornelis, Winnips, Didier, Leboulleux, Aditya H, Gaur, G Dennis, Shanks, James, McCarthy, Stephan, Chalon
Publikováno v:
The American Journal of Tropical Medicine and Hygiene
Malaria volunteer infection studies (VISs) accelerate new drug and vaccine development. In the induced blood-stage malaria (IBSM) model, volunteers are inoculated with erythrocytes infected with Plasmodium falciparum. Observations of elevated liver e
Autor:
Cantalloube C, Bernhards Ogutu, Otsula N, Peter G. Kremsner, Apollo D, Walsh Ds, Elhadj Djeriou, Christian Supan, Ghyslain Mombo-Ngoma, John N. Waitumbi, Mark E. Polhemus, Bertrand Lell, Ospina Salazar Cl, Maryvonne Kombila, Jana Held
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 97:514-525
Artemisinin-based combination therapies are recommended as first-line agents for treating uncomplicated Plasmodium falciparum malaria. Ferroquine, a 4-aminoquinolone, is a novel long-acting combination partner for fast-acting drugs like artesunate (A
Autor:
Chantal Din-Bell, Jana Held, Ali Sié, Carmen L. Ospina Salazar, Sodiomon B. Sirima, Alain Nahum, Léa Nadège Bonkian, Nekoye Otsyula, Lucas Otieno, Ahmed M Abdallah, Peter G. Kremsner, Bertrand Lell, Bancole Moulero, Robert Kimutai, Kimiko Koiwai, Mohamadou Siribié, Elhadj Djeriou, Cathy Cantalloube, Benjamin Mordmüller, Maryvonne Kombila, Marielle K. Bouyou-Akotet, Christian Supan, Daniel Ter-Minassian, Halidou Tinto, John N. Waitumbi, Boubacar Coulibaly
Publikováno v:
The Lancet Infectious Diseases. 15:1409-1419
Summary Background Artemisinin-based combination therapies (ACTs) are the recommended first-line treatment for uncomplicated Plasmodium falciparum malaria. Ferroquine is a new combination partner for fast-acting ACTs such as artesunate. We aimed to a
Autor:
Held, Jana, Supan, Christian, Salazar, Carmen, Halidou Tinto, LĂŠa Bonkian, Nahum, Alain, SiĂŠ, Ali, Abdulla, Salim, Cantalloube, Cathy, Elhadj Djeriou, Bouyou-Akotet, Marielle, Bernhards Ogutu, MordmĂźller, Benjamin, Kreidenweiss, Andrea, Siribie, Mohamadou, Sodiomon Sirima, Kremsner, Peter
Additional file 6. ECG parameters (Study 2). Table S2. Electrocardiogram abnormalities during TEAE period (Study2). Table S3. Respiratory parameters (Study 2).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa403e25d04d8947c0a7e0d2f0465cf
Autor:
Paul M. Griffin, James S. McCarthy, Elhadj Djeriou, Rob Hooft van Huijsduijnen, Cathy Cantalloube, Mark Baker, Thomas Rückle, Daniel Ter-Minassian, Jörg J. Möhrle, Peter O'Rourke, Louise Marquart
Publikováno v:
Malaria Journal
Background Ferroquine (SSR97193) is a candidate anti-malarial currently undergoing clinical trials for malaria. To better understand its pharmacokinetic (PK) and pharmacodynamic (PD) parameters the compound was tested in the experimentally induced bl
Autor:
Gansane, Adama1 (AUTHOR) agansane.cnrfp@fasonet.bf, Lingani, Moussa2 (AUTHOR), Yeka, Adoke3 (AUTHOR), Nahum, Alain4 (AUTHOR), Bouyou-Akotet, Marielle5 (AUTHOR), Mombo-Ngoma, Ghyslain6,7,8 (AUTHOR), Kaguthi, Grace9 (AUTHOR), Barceló, Catalina10 (AUTHOR), Laurijssens, Bart11 (AUTHOR), Cantalloube, Cathy12 (AUTHOR), Macintyre, Fiona10 (AUTHOR), Djeriou, Elhadj12 (AUTHOR), Jessel, Andreas13 (AUTHOR), Bejuit, Raphaël12 (AUTHOR), Demarest, Helen10 (AUTHOR), Marrast, Anne Claire10 (AUTHOR), Debe, Siaka1 (AUTHOR), Tinto, Halidou2 (AUTHOR), Kibuuka, Afizi3 (AUTHOR), Nahum, Diolinda4 (AUTHOR)
Publikováno v:
Malaria Journal. 1/3/2023, Vol. 22 Issue 1, p1-16. 16p.
Autor:
McCarthy, James, Rückle, Thomas, Elhadj Djeriou, Cantalloube, Cathy, Ter-Minassian, Daniel, Baker, Mark, O’Rourke, Peter, Griffin, Paul, Marquart, Louise, Huijsduijnen, Rob Hooft Van, Möhrle, Jörg
Additional file 1. McCarthy et al._Supplement. Supplementary data for probably related adverse events, detailed transaminase findings, individual parasite growth following inoculation (prior to ferroquine administration), pharmacokinetic model visual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::469d5f871c43c5c4acc5d1cec44cb74a