Suppressing NLRP3 activation and PI3K/AKT/mTOR signaling ameliorates amiodarone-induced pulmonary fibrosis in rats: a possible protective role of nobiletin.

Autor: El Tabaa MM; Pharmacology and Environmental Toxicology, Environmental Studies and Research Institute (ESRI), University of Sadat City, Sadat City, Minofia Governorate, Egypt. manar.eltabaa@esri.usc.edu.eg., El Tabaa MM; Medical Physiology, Faculty of Medicine, Tanta University, Tanta, Egypt., Elgharabawy RM; Pharmacology and Toxicology, Faculty of Pharmacy, Tanta University, Tanta, Egypt.; Pharmacology and Toxicology, College of Pharmacy, Qassim University, Buraydah, Kingdom of Saudi Arabia., Abdelhamid WG; Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Publikováno v: Inflammopharmacology [Inflammopharmacology] 2023 Jun; Vol. 31 (3), pp. 1373-1386. Date of Electronic Publication: 2023 Mar 22.

Innovative challenge for the inhibition of hepatocellular carcinoma progression by combined targeting of HSP90 and STAT3/HIF-1α signaling.

Autor: Saber S; Department of Pharmacology, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa 11152, Egypt. Electronic address: sampharm81@gmail.com., El-Fattah EEA; Department of Biochemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa 11152, Egypt. Electronic address: eslam_620@yahoo.com., Abdelhamid AM; Department of Pharmacology, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa 11152, Egypt. Electronic address: amir_algendy@yahoo.com., Mourad AAE; Pharmacology and Toxicology Department, Faculty of Pharmacy, Port-Said University, Port-Said 42511, Egypt. Electronic address: ahmed.mourad@yahoo.com., Hamouda MAM; Clinical Pharmacy Department, Faculty of Pharmacy, Menoufia University, Menoufia 32511, Egypt. Electronic address: manalhamouda124@gmail.com., Elrabat A; Gastroenterology and Hepatology Department, Faculty of Medicine, Mansoura University, Mansoura 35516, Egypt. Electronic address: amr.rabat@yahoo.com., Zakaria S; Department of Tropical Medicine, Faculty of Medicine, Mansoura University, Mansoura 35516, Egypt. Electronic address: sahar@mans.edu.eg., Haleem AA; Medical Biochemistry and Molecular Biology Department, Faculty of Medicine, Mansoura University, Mansoura 35516, Egypt. Electronic address: mero2015up@gmail.com., Mohamed SZ; Department of Internal Medicine, Faculty of Medicine, Horus University, New Damietta 34518, Egypt. Electronic address: shzohdy@horus.edu.eg., Elgharabawy RM; Pharmacology and Toxicology Department, Faculty of Pharmacy, Tanta University, Tanta 31527, Egypt. Electronic address: drrehab200932@yahoo.com., Morsy NE; Pulmonary Medicine Department, Mansoura University Sleep Center, Faculty of Medicine, Mansoura University, Mansoura 35516, Egypt. Electronic address: neselmorsy@mans.edu.eg., El Adle Khalaf N; Department of Clinical Pharmacology, Faculty of Medicine, Mansoura University, Mansoura 35516, Egypt. Electronic address: nouraeladle@mans.edu.eg., Mohammed OA; Department of Clinical Pharmacology, Faculty of Medicine, Ain Shams University, Cairo 11566, Egypt. Electronic address: osamaabbass@med.asu.edu.eg., El-Bahouty WB; Pharmacology Department, Faculty of Medicine, Tanta University, Tanta 31527, Egypt. Electronic address: wbpharmacology@gmail.com., Mostafa SA; Medical Biochemistry and Molecular Biology Department, Faculty of Medicine, Mansoura University, Mansoura 35516, Egypt. Electronic address: sallyabdallah@mans.edu.eg., Abdelhady R; Pharmacology and Toxicology Department, Faculty of Pharmacy, Fayoum University, Fayoum, Egypt. Electronic address: ram14@fayoum.edu.eg., Galal O; Department of Pharmacology, Faculty of Pharmacy, Ahram Canadian University, Giza 12451, Egypt. Electronic address: omneyagalal@hotmail.com., ElSaid ZH; Department of Medical Physiology, Faculty of Medicine, Mansoura University, Mansoura 35516, Egypt. Electronic address: Zeinabelsaid1@gmail.com., Yahya G; Department of Microbiology and Immunology, Faculty of Pharmacy, Zagazig University, Al Sharqia 44519, Egypt. Electronic address: galalyehia@zu.edu.eg., Shata A; Department of Clinical Pharmacology, Faculty of Medicine, Mansoura University, Mansoura 35516, Egypt; Department of Clinical Pharmacy, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa 11152, Egypt. Electronic address: ahmedmhes@mans.edu.eg., Youssef ME; Department of Pharmacology, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa 11152, Egypt. Electronic address: Mahmoodelsaid@hotmail.com.

Publikováno v: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2023 Feb; Vol. 158, pp. 114196. Date of Electronic Publication: 2023 Jan 02.

Ambroxol, a mucolytic agent, boosts HO-1, suppresses NF-κB, and decreases the susceptibility of the inflamed rat colon to apoptosis: A new treatment option for treating ulcerative colitis.

Autor: Cavalu S; Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania., Sharaf H; Department of Biochemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt., Saber S; Department of Pharmacology, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt., Youssef ME; Department of Pharmacology, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt., Abdelhamid AM; Department of Pharmacology, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt., Mourad AAE; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Port Said University, Port Said, Egypt., Ibrahim S; Department of Pharmacy Practice, Faculty of Pharmacy, Ahram Canadian University, Giza, Egypt., Allam S; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Menoufia University, Menoufia, Egypt., Elgharabawy RM; Pharmacology and Toxicology Department, Faculty of Pharmacy, Tanta University, Tanta, Egypt., El-Ahwany E; Department of Immunology, Theodor Bilharz Research Institute, Giza, Egypt., Amin NA; Department of Haematology, Theodor Bilharz Research Institute, Giza, Egypt., Shata A; Department of Clinical Pharmacology, Faculty of Medicine, Mansoura University, Mansoura, Egypt.; Department of Clinical Pharmacy, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt., Eldegla M; Department of Biochemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt., Atef M; Department of Biochemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt., Aboraya M; Department of Biochemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt., Mohamed M; Department of Biochemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt., Anz N; Department of Biochemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt., Elmotelb DA; Department of Biochemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt., Gabr F; Department of Biochemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt., Elzablawy D; Department of Biochemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt., Hamada M; Department of Biochemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt., Yehia A; Department of Biochemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt., Osama D; Department of Biochemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt., Mohammed OA; Department of Clinical Pharmacology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.; Department of Clinical Pharmacology, Faculty of medicine, Bisha University, Bisha, Saudi Arabia.

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2022 Sep; Vol. 36 (9), pp. e22496.

Carbocisteine as a Modulator of Nrf2/HO-1 and NFκB Interplay in Rats: New Inspiration for the Revival of an Old Drug for Treating Ulcerative Colitis.

Autor: Abdelhamid AM; Department of Pharmacology, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt., Youssef ME; Department of Pharmacology, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt., Cavalu S; Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania., Mostafa-Hedeab G; Pharmacology Department and Health Research Unit, Medical College, Jouf University, Sakakah, Saudi Arabia.; Pharmacology Department, Faculty of Medicine, Beni-Suef University, Beni Suef, Egypt., Youssef A; Medical Pharmacology Department, Faculty of Medicine, Cairo University, Giza, Egypt., Elazab ST; Department of Pharmacology, Faculty of Veterinary Medicine, Mansoura University, Mansoura, Egypt., Ibrahim S; Department of Pharmacy Practice, Faculty of Pharmacy, Ahram Canadian University, Giza, Egypt., Allam S; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Menoufia University, Menoufia, Egypt., Elgharabawy RM; Pharmacology and Toxicology Department, Faculty of Pharmacy, Tanta University, Tanta, Egypt., El-Ahwany E; Department of Immunology, Theodor Bilharz Research Institute, Giza, Egypt., Amin NA; Department of Haematology, Theodor Bilharz Research Institute, Giza, Egypt., Shata A; Department of Clinical Pharmacology, Faculty of Medicine, Mansoura University, Mansoura, Egypt.; Department of Clinical Pharmacy, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt., Mohammed OA; Department of Clinical Pharmacology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.; Department of Clinical Pharmacology, Faculty of Medicine, Bisha University, Bisha, Saudi Arabia., Ibrahim Abdeldaiem MS; Clinical Pharmacy Department, School of Pharmaceutical Sciences, Universiti Sains Malaysia, George Town, Malaysia.; Pharmacy Practice Department, Faculty of Pharmacy, Sinai University, Ismailia, Egypt., Alhowail A; Department of Pharmacology and Toxicology, College of Pharmacy, Qassim University, Buraidah, Saudi Arabia., El-Saber Batiha G; Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour, Egypt., El-Mahmoudy EA; Department of Biochemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt., Attia M; Department of Biochemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt., Allam A; Department of Biochemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt., Zaater MY; Department of Biochemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt., Osman MM; Department of Biochemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt., Nader M; Department of Biochemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt., Taha A; Department of Biochemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt., Makarem NA; Department of Biochemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt., Saber S; Department of Pharmacology, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt.

Publikováno v: Frontiers in pharmacology [Front Pharmacol] 2022 Jun 08; Vol. 13, pp. 887233. Date of Electronic Publication: 2022 Jun 08 (Print Publication: 2022).

Nifuroxazide-loaded cubosomes exhibit an advancement in pulmonary delivery and attenuate bleomycin-induced lung fibrosis by regulating the STAT3 and NF-κB signaling: A new challenge for unmet therapeutic needs.

Autor: Saber S; Department of Pharmacology, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa 11152, Egypt. Electronic address: sampharm81@gmail.com., Nasr M; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Helwan University, Cairo 11790, Egypt; Department of Pharmaceutics, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt. Electronic address: m2nasr@yahoo.com., Kaddah MMY; Pharmaceutical and Fermentation Industries Development Center, City of Scientific Research and Technological Applications, New Borg El-Arab 21934, Alexandria, Egypt. Electronic address: mmkaddah1978@gmail.com., Mostafa-Hedeab G; Pharmacology Department & Health Research Unit, Medical College, Jouf University, Saudi Arabia; Pharmacology Department, Faculty of Medicine, Beni-Suef University, Beni Suef, Egypt. Electronic address: gomaa@ju.edu.sa., Cavalu S; Faculty of Medicine and Pharmacy, University of Oradea, P-ta 1 Decembrie 10, 410087 Oradea, Romania. Electronic address: simona.cavalu@gmail.com., Mourad AAE; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Port Said University, Port Said 42511, Egypt. Electronic address: ahmed.mourad@yahoo.com., Gaafar AGA; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Port Said University, Port Said 42511, Egypt. Electronic address: agafer777@yahoo.com., Zaghlool SS; Pharmacology and Toxicology Department, Faculty of Pharmacy, Modern University for Technology and Information (MTI), Mokattam, Cairo 11571, Egypt. Electronic address: samehsaadzaghlool@yahoo.com., Saleh S; Department of Clinical Physiology, Faculty of Medicine, Menoufia University, Menoufia, Egypt. Electronic address: safaa_kotb48@yahoo.com., Hafez MM; Department of Biochemistry, Faculty of Pharmacy, Ahram Canadian University, Giza, Egypt. Electronic address: mohkhalifa2000@yahoo.com., Girgis S; Department of Pharmaceutics, Faculty of Pharmacy, Alsalam University, Egypt. Electronic address: girgissamuel2@gmail.com., Elgharabawy RM; Pharmacology and Toxicology Department, Faculty of Pharmacy, Tanta University, Tanta, Egypt. Electronic address: drrehab200932@yahoo.com., Nader K; Department of Biochemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa 11152, Egypt. Electronic address: kareemnadersamra@gmail.com., Alsharidah M; Department of Physiology, College of Medicine, Qassim University, Qassim 51452, Kingdom of Saudi Arabia. Electronic address: malsharidah@qu.edu.sa., Batiha GE; Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour 22511, AlBeheira, Egypt. Electronic address: gaberbatiha@gmail.com., El-Ahwany E; Department of Immunology, Theodor Bilharz Research Institute, Giza 12411, Egypt. Electronic address: ahwany@aucegypt.edu., Amin NA; Department of Haematology, Theodor Bilharz Research Institute, Giza 12411, Egypt. Electronic address: esmaealn78@gmail.com., Elagamy HI; Department of Pharmaceutics, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt. Electronic address: hebaelagamy1985@yahoo.com., Shata A; Department of Clinical Pharmacology, Faculty of Medicine, Mansoura University, Mansoura, Egypt; Department of Clinical Pharmacy, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt. Electronic address: ahmedmhes@mans.edu.eg., Nader R; Department of Biochemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa 11152, Egypt. Electronic address: reemnadersamra@gmail.com., Khodir AE; Department of Pharmacology, Faculty of Pharmacy, Horus University, New Damietta, Egypt. Electronic address: Dr.ahmed_esam@yahoo.com.

Publikováno v: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2022 Apr; Vol. 148, pp. 112731. Date of Electronic Publication: 2022 Feb 24.