Výsledky vyhledávání - "Elfriede G. Van den Eeckhout"

Analysis of benzo[a]pyrene diol epoxide-DNA adducts by capillary zone electrophoresis- electrospray ionization-mass spectrometry in conjunction with sample stacking

Autor: Dieter Deforce, Elfriede G. Van den Eeckhout, An Willems, Jan Van Bocxlaer, André P. De Leenheer, Willy E. Lambert, Carlos Van Peteghem

Publikováno v: ELECTROPHORESIS. 23:4092-4103

Benzo[a]pyrene diol epoxide (BPDE) was reacted in vitro with (2'-deoxy)nucleotides and with calf thymus DNA. The modified DNA was enzymatically hydrolyzed to the 5'-monophosphate nucleotides using deoxyribonuclease I (DNA-ase I), nuclease P1 and snak

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::404f65cc23b5566615a6149abc342841
https://doi.org/10.1002/elps.200290026

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Evaluation of automated single mass spectrometry to tandem mass spectrometry function switching for comprehensive drug profiling analysis using a quadrupole time-of-flight mass spectrometer

Autor: Carlos Van Peteghem, André P. De Leenheer, Elfriede G. Van den Eeckhout, Jan Van Bocxlaer, Tineke N. Decaestecker, Karine M. Clauwaert, Willy E. Lambert

Publikováno v: Rapid Communications in Mass Spectrometry. 14:1787-1792

A liquid chromatographic mass spectrometric strategy for systematic toxicological analysis (STA) is presented using the automatic 'on-the-fly' single mass spectrometry mode to tandem mass spectrometry mode (MS to MS/MS) switching abilities of a quadr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ce1a38315a53cb2a3e639a21b7a7ba15
https://doi.org/10.1002/1097-0231(20001015)14:19<1787::aid-rcm94>3.0.co

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Preparative capillary zone electrophoresis in combination with off-line graphite furnace atomic absorption for the analysis of DNA complexes formed by a new aminocoumarine platinum (II) compound

Autor: Dieter Deforce, Andreas De Leenheer, George Kokotos, Elfriede G. Van den Eeckhout, Eddy L. Esmans

Publikováno v: Electrophoresis. 19:2454-2458

Calf thymus DNA was incubated in vitro with a new aminocoumarin platinum (II) complex in order to study its interaction with DNA. The platinated DNA was hydrolyzed enzymatically to the 5'-mononucleotide level using DNAase I and nuclease P1. Analysis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bff5f442a98a4d30fa6676359c12d4f9
https://doi.org/10.1002/elps.1150191417

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Characterization of DNA Oligonucleotides by Coupling of Capillary Zone Electrophoresis to Electrospray Ionization Q-TOF Mass Spectrometry

Autor: Elfriede G. Van den Eeckhout, Jos Raymackers, Frans Van Wijnendaele, and Andreas De Leenheer, Lydie Meheus, Dieter Deforce

Publikováno v: Analytical Chemistry. 70:3060-3068

A procedure for fast and precise molecular weight, purity, and base composition determination of oligonucleotides (in the size range of 20−120 bases) using capillary zone electrophoresis (CZE) coupled by an electrospray interface (ES) on-line to a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::364dc619eaa1ca7b4c936740edeb7ee6
https://doi.org/10.1021/ac980147x

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Population genetic study of four short tandem repeat loci in the Belgian population, using capillary electrophoresis

Autor: V. Brochez, Annemieke Vergauwe, Elfriede G. Van den Eeckhout, Els Van Geldre, Dieter Deforce, Rebecca E. M. Millecamps, David Van Hoofstat, Annick Sijs

Publikováno v: Electrophoresis. 19:719-722

Allele frequencies of four short tandem repeat loci (HumCD4, HumTH01, HumD21S11 and HumSE33) were investigated in a sample of 395 unrelated Belgian individuals using multiplex polymerase chain reaction and capillary electrophoresis. Automated laser f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7a7451ebaefb49f564adee2dba1725c
https://doi.org/10.1002/elps.1150190520

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Differentiation between isomeric phenylglycidyl ether adducts of 2'-deoxyguanosine and 2'-deoxyguanosine-5'-monophosphate using liquid chromatography/electrospray tandem mass spectrometry

Autor: Magda Claeys, Eddy L. Esmans, Harry Van Onckelen, Filip Lemière, Radek Marek, K. Vanhoutte, Elfriede G. Van den Eeckhout, Tim H. M. Jonckers

Publikováno v: Journal of mass spectrometry

The reaction between phenylglycidyl ether and 2'-deoxyguanosine or 2'-deoxyguanosine-5'-monophosphate yields a variety of different nucleoside and nucleotide adducts. The corresponding mixtures were analyzed by liquid chromatography/electrospray tand

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::029fdb028000d99de52429f36a962493
https://hdl.handle.net/10067/255350151162165141

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Comparison of slab gel electrophoresis and capillary electrophoresis for the detection of the fluorescently labeled polymerase chain reaction products of short tandem repeat fragments

Autor: Elfriede G. Van den Eeckhout, David Van Hoofstat, Dieter Deforce, Rebecca E. M. Millecamps

Publikováno v: Journal of chromatography. A. 806(1)

The sizing capability of slab gel electrophoresis for short tandem repeat (STR) fragments was compared to the sizing capability of capillary electrophoresis (CE). Both systems used automated laser fluorescence detection to detect four fluorescent dye

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83f21dd8c381b506f32d537a8c153d4e
https://pubmed.ncbi.nlm.nih.gov/9639885

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Analysis of the DNA damage induced by phenylglycidyl ether using capillary zone electrophoresis-electrospray mass spectrometry

Autor: Andreas De Leenheer, Eddy L. Esmans, Elfriede G. Van den Eeckhout, Dieter Deforce, Filip Lemière

Publikováno v: Analytical biochemistry

The in vitro adduct formation between phenyl glycidyl ether (PGE) and calf thymus DNA was inves-tigated. Agarose slab gel electrophoresis of DNA incubated with PGE revealed that nearly all high-molecular-weight species were degraded after 10 h of inc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62b1cff8af95054d0fcd6a8432168690
https://hdl.handle.net/10067/252530151162165141

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Analysis of DNA-adducts in DNA hydrolysates by capillary zone electrophoresis and capillary zone electrophoresis electrospray mass-spectrometry

Autor: Eddy L. Esmans, Dieter Deforce, Filip Lemière and, Elfriede G. Van den Eeckhout, and Filip P. K. Ryniers

Publikováno v: Analytical chemistry

The in vitro adduct formation with phenyl glycidyl ethers (PGEs) was studied on 2'-deoxynucleotides and DNA. The modified DNA was hydrolyzed enzymatically, and the mixtures consisting of unmodified 2'-deoxynucleotide adducts were analyzed by capillar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f62349e89bf8c5f2a9c670bf66bb8693
https://hdl.handle.net/10067/149330151162165141

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