Zobrazeno 1 - 10 of 237 pro vyhledávání: '"Elferink, R. P."'
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Cholestatic pruritus. New insights into pathophysiology and current treatment
Autor: Kremer, A. E., Oude Elferink, R. P. J., Beuers, U.
Publikováno v: Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete, 63(7), 532-538. Springer Verlag
Pruritus is a common symptom of hepatobiliary disorders and may considerably diminish quality of life. Cholestatic pruritus exerts a circadian rhythm and is typically most severe in the evening hours and early at night. Itching is reported often to b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::698ac491f33692c65452bee843844148
https://pure.amc.nl/en/publications/cholestatic-pruritus-new-insights-into-pathophysiology-and-current-treatment(da1d4442-5966-49bb-89e4-f337bf2702ec).html
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9
Increased bioavailability of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in MRP2-deficient rats
Autor: Dietrich, C. G., de Waart, D. R., Ottenhoff, R., Schoots, I. G., Elferink, R. P.
Publikováno v: Molecular pharmacology, 59(5), 974-980. American Society for Pharmacology and Experimental Therapeutics
MRP2 is an apical transporter expressed in hepatocytes and the epithelial cells of the small intestine and kidney proximal tubule. It extrudes organic anions, conjugated compounds, and some uncharged amphipaths. We studied the transport of an abundan
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::0c53597a0683dc93dcc4768f6b1f7653
https://pure.amc.nl/en/publications/increased-bioavailability-of-the-foodderived-carcinogen-2amino1methyl6phenylimidazo45bpyridine-in-mrp2deficient-rats(be5a74e8-a4a5-4cb9-99c0-d9b8e6f31bfd).html
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10
MDR1 P-glycoprotein transports endogenous opioid peptides
Autor: Oude Elferink, R. P., Zadina, J.
Publikováno v: Peptides, 22(12), 2015-2020. Elsevier Inc.
MDR1 P-glycoprotein is generally regarded as an efflux pump for amphipathic toxic compounds. The question remains, however, whether certain endogenous compounds are also substrates for this transporter. Certain peptides have been shown to interact wi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::7c1097288c1875743012ebd22cadb221
https://pure.amc.nl/en/publications/mdr1-pglycoprotein-transports-endogenous-opioid-peptides(9a9d9905-a160-431f-8c5b-06076d899218).html
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