Výsledky vyhledávání - "Elferink, Maria"

Organ-specific candidate biomarkers of inflammation found by comparative analyses of the human hepatic and adipose tissue transcriptome and secretome during LPS treatment

Autor: Vonk, Roelf, Szalowska, Ewa, Dijkstra, Martijn L., Weening, Desireé, de Vries, Marcel, Roelofsen, Han, Bruinenberg, Marcel, Hoek, Annemieke, Elferink, Maria, Groothuis, Genoveva

Publikováno v: Diabetes, 60(Supplement 1A), LB26-LB26. AMER DIABETES ASSOC

Insulin resistance (IR) is accompanied by chronic low grade systemic inflammation and deregulation of total body energy homeostasis. We induced inflammation in human adipose and liver tissue in vitro in order to mimic inflammation in vivo with the ai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::54b5d2f67683dca1f3bed30afd512ee7
https://research.rug.nl/en/publications/e09b2488-e733-488e-96e9-2863e5101ddf

Zobrazit plný text záznamu

Gene expression analysis of precision-cut human liver slices indicate stable expression of hepatotoxicity related genes

Autor: Elferink, Maria, Olinga, Peter, van Leeuwen, E. M., Bauerschmidt, S., Polman, J., Schoonen, W. G., Heisterkamp, S. H., Groothuis, Genoveva

Publikováno v: The Toxicologist. Supplement to Toxicological Sciences, 120(Supplement 2), 548-548

In the process of drug development it is of high importance to test the safety of new drugs with predictive value for human toxicity. A promising approach of toxicity testing is based on changes in the gene expression profile of the liver. Toxicity s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::a9e6f5e38c26ea39d93f9425230d16d6
https://research.rug.nl/en/publications/8a014ca5-dfd8-4dd3-b803-4052ef5805af

Zobrazit plný text záznamu

FUNCTIONAL RECONSTITUTION OF THE PURIFIED PHOSPHOENOLPYRUVATE-DEPENDENT MANNITOL-SPECIFIC TRANSPORT-SYSTEM OF ESCHERICHIA-COLI IN PHOSPHOLIPID-VESICLES - COUPLING BETWEEN TRANSPORT AND PHOSPHORYLATION

Autor: Elferink, Maria, Driessen, A.J.M., Robillard, G.T.

Publikováno v: Journal of Bacteriology, 172(12), 7119-7125. AMER SOC MICROBIOLOGY

Purified mannitol-specific enzyme II (EII) from Escherichia coli was reconstituted into phospholipid vesicles with the aid of a detergent-dialysis procedure followed by a freeze-thaw sonication step. The orientation of EII in the proteoliposomes was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::7fc7930c55c6276055bb74000b02f610
https://research.rug.nl/en/publications/738c3ec4-e320-46a9-9d21-03e304ce8f71

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání