Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Elevated transferrin saturation"'
Publikováno v:
European Journal of Gastroenterology & Hepatology. 34:316-323
OBJECTIVE To determine whether a low aspartate aminotransferase (AST) to alanine aminotransferase (ALT) ratio (AST/ALT ratio) is associated with insulin resistance among those without liver dysfunction. METHODS In this cross-sectional study of the Na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ec9add8774596158589e5e64d7903e
https://doi.org/10.1097/meg.0000000000002215
https://doi.org/10.1097/meg.0000000000002215
Autor:
Paul C. Adams, James C. Barton
Publikováno v:
Can Liver J
Background: Elevated transferrin saturation (TS) is an imperfect test to identify adults with high-iron gene ( HFE) p.C282Y homozygosity or elevated hepatic iron concentration. Methods: We analyzed observations of non-screening, previously untreated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b27df8a922f225e4a51ed3ff280018d
https://doi.org/10.3138/canlivj.2019-0013
https://doi.org/10.3138/canlivj.2019-0013
Akademický článek
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Publikováno v:
Journal of Clinical and Experimental Hepatology. 7:269-273
Elevated serum ferritin level is a common finding in iron overload syndrome, autoimmune and viral hepatitis, alcoholic and nonalcoholic fatty liver diseases. High transferrin saturation is not a common finding in above diseases except for iron overlo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8ed156d3b2a73f9a1a3cad590ec5341
https://doi.org/10.1016/j.jceh.2017.03.006
https://doi.org/10.1016/j.jceh.2017.03.006
Autor:
Hakan Çam, Nimet Yılmaz
Publikováno v:
Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology. 21(2)
The clinical significance of serum parameters of iron metabolism and hepcidin in liver disease remains unknown. Therefore, this study aimed to evaluate the association of serum hepcidin levels with fibrosis stage and serum iron parameters in patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98b058f9a15c27f5d521d07dd313095f
https://pubmed.ncbi.nlm.nih.gov/32423859
https://pubmed.ncbi.nlm.nih.gov/32423859
Akademický článek
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Publikováno v:
Laboratory medicine. 50(2)
Hereditary hemochromatosis (HH) is an autosomal recessive disorder of iron metabolism characterized by increased iron absorption and tissue deposition. Three loss-of-function mutations in the hemochromatosis gene (HFE), namely, C282Y (c.845G>A), H63D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b436ea9e5ee72ce5fc583b3df0bbe97f
https://pubmed.ncbi.nlm.nih.gov/30339210
https://pubmed.ncbi.nlm.nih.gov/30339210
Publikováno v:
Diabetes/Metabolism Research and Reviews. 30:372-394
The literature on the role of body iron status in the development of type 2 diabetes (T2D) in humans is inconsistent. We aimed to assess the association between iron indices and T2D by a meta-analysis of previously published studies. A systematic lit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef47455efe1c48349c3a5e5f1fdcf3ba
https://doi.org/10.1002/dmrr.2506
https://doi.org/10.1002/dmrr.2506
Autor:
Yves Deugnier, Martine Ropert, Patricia Leroyer, Lénaïck Détivaud, Caroline Le Lan, Annick Mosser, Véronique David, Pierre Brissot, Edouard Bardou-Jacquet, Olivier Loréal, Marie-Laure Island, Anne-Marie Jouanolle
Publikováno v:
Human Mutation
Human Mutation, Wiley, 2013, 34 (11), pp.1529-36. ⟨10.1002/humu.22396⟩
Human Mutation, 2013, 34 (11), pp.1529-36. ⟨10.1002/humu.22396⟩
Human Mutation, Wiley, 2013, 34 (11), pp.1529-36. ⟨10.1002/humu.22396⟩
Human Mutation, 2013, 34 (11), pp.1529-36. ⟨10.1002/humu.22396⟩
International audience; Ferroportin (FPN) mediates iron export from cells and this function is modulated by serum hepcidin. Mutations in the FPN gene (SLC40A1) lead to autosomal dominant iron overload diseases related either to loss or to gain of fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a465a469174c474fe8fc46c33c91277
https://doi.org/10.1002/humu.22396
https://doi.org/10.1002/humu.22396
Autor:
Anne Tybjærg-Hansen, Henrik Ullitis Andersen, Christina Ellervik, Henrik Birgens, Merete Frandsen, Thomas Mandrup-Poulsen, Børge G. Nordestgaard
Publikováno v:
Diabetes Care
OBJECTIVE It is not known to what extent iron overload predicts prognosis in patients with diabetes after diagnosis or whether iron overload is a risk factor independent of the HFE genotype. We investigated total and cause-specific mortality accordin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bf4c2a51f6bc7958e80572e5e8c8b88
https://doi.org/10.2337/dc12-2032
https://doi.org/10.2337/dc12-2032