Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Eleuterio, Lombardo"'
Autor:
Maitane Ortiz-Virumbrales, Ramón Menta, Laura M. Pérez, Ornella Lucchesi, Pablo Mancheño-Corvo, Álvaro Avivar-Valderas, Itziar Palacios, Angel Herrero-Mendez, Wilfried Dalemans, Olga de la Rosa, Eleuterio Lombardo
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-21 (2020)
Abstract Background Mesenchymal stem cells (MSCs) activate the endogenous immune regulatory system, inducing a therapeutic effect in recipients. MSCs have demonstrated the ability to modulate the differentiation of myeloid cells toward a phagocytic a
Externí odkaz:
https://doaj.org/article/01ff2df1e9774c30abd5f588892eb66d
Publikováno v:
Stem Cells Translational Medicine, Vol 8, Iss 11, Pp 1126-1134 (2019)
Summary 2018 was the year of the first marketing authorization of an allogeneic stem cell therapy by the European Medicines Agency. The authorization concerns the use of allogeneic adipose tissue‐derived mesenchymal stromal cells (MSCs) for treatme
Externí odkaz:
https://doaj.org/article/ae4c0f6b1d2d48eaa4d774369996a0f7
Autor:
Hocine Rachid Hocine, Simon Brunel, Qian Chen, Jerome Giustiniani, Mabel Jouve San Roman, Yann J. Ferrat, Itziar Palacios, Olga de laRosa, Eleuterio Lombardo, Armand Bensussan, Dominique Charron, Nabila Jabrane‐Ferrat, Reem Al‐Daccak
Publikováno v:
Stem Cells Translational Medicine, Vol 8, Iss 9, Pp 911-924 (2019)
Abstract The positive effects of therapeutic human allogeneic cardiac stem/progenitor cells (hCPC) in terms of cardiac repair/regeneration are very likely mediated by paracrine effects. Our previous studies revealed the advantageous immune interactio
Externí odkaz:
https://doaj.org/article/d39724720ec14bf7a4af7832d3e10665
Autor:
Desirée Perlee, Alex F. de Vos, Brendon P. Scicluna, Anja Maag, Pablo Mancheño, Olga de la Rosa, Wilfried Dalemans, Sandrine Florquin, Cornelis van’t Veer, Eleuterio Lombardo, Tom van der Poll
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-9 (2019)
Abstract Background Adult mesenchymal stem cells (MSCs) improve the host response during experimental sepsis in animals. MSCs from various sources express a procoagulant activity that has been linked to the expression of tissue factor. This study sou
Externí odkaz:
https://doaj.org/article/9ae00b646c894373ae7289ae8e6bde7c
Autor:
Desiree Perlee, Alex F. deVos, Brendon P. Scicluna, Pablo Mancheño, Olga de laRosa, Wilfried Dalemans, Peter Nürnberg, Eleuterio Lombardo, Tom van derPoll
Publikováno v:
Stem Cells Translational Medicine, Vol 8, Iss 8, Pp 785-796 (2019)
Abstract Adult mesenchymal stem cells exert immunomodulatory effects that might improve the host response during sepsis. Knowledge on the effect of adipose‐derived mesenchymal stem cells (ASCs) in sepsis is limited. Klebsiella (K.) pneumoniae is a
Externí odkaz:
https://doaj.org/article/2efa4294d749420091c6c7d30263edbc
Autor:
Ana Merino, Marta Sablik, Sander S. Korevaar, Carmen López-Iglesias, Maitane Ortiz-Virumbrales, Carla C. Baan, Eleuterio Lombardo, Martin J. Hoogduijn
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Proinflammatory stimuli lead to endothelial injury, which results in pathologies such as cardiovascular diseases, autoimmune diseases, and contributes to alloimmune responses after organ transplantation. Both mesenchymal stromal cells (MSC) and the e
Externí odkaz:
https://doaj.org/article/6c529fdd1fda4069a5ef572daec04477
Autor:
Fabiany da Costa Gonçalves, Sander S. Korevaar, Maitane Ortiz Virumbrales, Carla C. Baan, Marlies E. J. Reinders, Ana Merino, Eleuterio Lombardo, Martin J. Hoogduijn
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Mesenchymal stromal cells (MSC) are a promising therapy for inflammatory diseases. However, MSC are large and become trapped in the lungs after intravenous infusion, where they have a short survival time. To steer MSC immunoregulatory therapy beyond
Externí odkaz:
https://doaj.org/article/d3a52806923b47a19ac2f960e547d895
Autor:
Maria J Sebastião, Ramón Menta, Margarida Serra, Itziar Palacios, Paula M Alves, Belén Sanchez, Olga DelaRosa, Wilfried Dalemans, Eleuterio Lombardo, Patrícia Gomes-Alves
Publikováno v:
Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-7 (2018)
Abstract Transplantation of allogeneic human cardiac/stem progenitor cells (hCSCs) is currently being tested in several phase I/II clinical trials as a novel and promising therapy for restoration of myocardial tissue function in acute myocardial infa
Externí odkaz:
https://doaj.org/article/b3b36214681c469da6198d1aacffb11d
Autor:
Eduardo Martín Arranz, María Dolores Martín Arranz, Tomás Robredo, Pablo Mancheño-Corvo, Ramón Menta, Francisco Javier Alves, Jose Manuel Suárez de Parga, Pedro Mora Sanz, Olga de la Rosa, Dirk Büscher, Eleuterio Lombardo, Fernando de Miguel
Publikováno v:
Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-13 (2018)
Abstract Background Mesenchymal stem cells have potential applications in inflammatory bowel disease due to their immunomodulatory properties. Our aim was to evaluate the feasibility, safety and efficacy of endoscopic administration of adipose-derive
Externí odkaz:
https://doaj.org/article/0f3ed5bfa1e745fe9736f3753fe7a310
Autor:
Alvaro Avivar-Valderas, Cristina Martín-Martín, Cristina Ramírez, Borja Del Río, Ramón Menta, Pablo Mancheño-Corvo, Maitane Ortiz-Virumbrales, Ángel Herrero-Méndez, Julián Panés, Damián García-Olmo, José Luís Castañer, Itziar Palacios, Eleuterio Lombardo, Wilfried Dalemans, Olga DelaRosa
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Adipose mesenchymal stem cells (ASC) are considered minimally immunogenic. This is due to the low expression of human leukocyte antigens I (HLA-I), lack of HLA-II expression and low expression of co-stimulatory molecules such as CD40 and CD80. The lo
Externí odkaz:
https://doaj.org/article/da603270daf8404c98bf9261db4f3fa5