A microRNA signature that correlates with cognition and is a target against cognitive decline.

Autor: Islam MR; Department for Epigenetics and Systems Medicine in Neurodegenerative Diseases, German Center for Neurodegenerative Diseases, Göttingen, Germany., Kaurani L; Department for Epigenetics and Systems Medicine in Neurodegenerative Diseases, German Center for Neurodegenerative Diseases, Göttingen, Germany.; Department for Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany., Berulava T; Department for Epigenetics and Systems Medicine in Neurodegenerative Diseases, German Center for Neurodegenerative Diseases, Göttingen, Germany., Heilbronner U; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, Ludwig-Maximilians-University Munich, Munich, Germany., Budde M; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, Ludwig-Maximilians-University Munich, Munich, Germany., Centeno TP; Department for Epigenetics and Systems Medicine in Neurodegenerative Diseases, German Center for Neurodegenerative Diseases, Göttingen, Germany., Elerdashvili V; Department for Epigenetics and Systems Medicine in Neurodegenerative Diseases, German Center for Neurodegenerative Diseases, Göttingen, Germany., Zafieriou MP; Institute of Pharmacology and Toxicology, University Medical Center Göttingen, Göttingen, Germany., Benito E; Department for Epigenetics and Systems Medicine in Neurodegenerative Diseases, German Center for Neurodegenerative Diseases, Göttingen, Germany., Sertel SM; Department of Neuro- and Sensory Physiology, University Medical Center Göttingen, Göttingen, Germany., Goldberg M; Department for Epigenetics and Systems Medicine in Neurodegenerative Diseases, German Center for Neurodegenerative Diseases, Göttingen, Germany., Senner F; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, Ludwig-Maximilians-University Munich, Munich, Germany.; Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University Munich, München, Germany., Kalman JL; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, Ludwig-Maximilians-University Munich, Munich, Germany.; Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University Munich, München, Germany., Burkhardt S; Department for Epigenetics and Systems Medicine in Neurodegenerative Diseases, German Center for Neurodegenerative Diseases, Göttingen, Germany., Oepen AS; Department for Epigenetics and Systems Medicine in Neurodegenerative Diseases, German Center for Neurodegenerative Diseases, Göttingen, Germany., Sakib MS; Department for Epigenetics and Systems Medicine in Neurodegenerative Diseases, German Center for Neurodegenerative Diseases, Göttingen, Germany., Kerimoglu C; Department for Epigenetics and Systems Medicine in Neurodegenerative Diseases, German Center for Neurodegenerative Diseases, Göttingen, Germany., Wirths O; Department for Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany., Bickeböller H; Department of Genetic Epidemiology, University Medical Center Göttingen, Göttingen, Germany., Bartels C; Department for Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany., Brosseron F; German Center for Neurodegenerative Diseases, Bonn, Germany.; Department of Neurodegeneration and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany., Buerger K; German Center for Neurodegenerative Diseases (DZNE, Munich), Munich, Germany.; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany., Cosma NC; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin, Berlin, Germany., Fliessbach K; German Center for Neurodegenerative Diseases, Bonn, Germany.; Department of Neurodegeneration and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany., Heneka MT; German Center for Neurodegenerative Diseases, Bonn, Germany.; Department of Neurodegeneration and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany., Janowitz D; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany., Kilimann I; German Center for Neurodegenerative Diseases (DZNE), Rostock, Germany.; Department of Psychosomatic Medicine, Rostock University Medical Center, Rostock, Germany., Kleinedam L; German Center for Neurodegenerative Diseases, Bonn, Germany.; Department of Neurodegeneration and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany., Laske C; Department of Psychosomatic Medicine, Rostock University Medical Center, Rostock, Germany.; Section for Dementia Research, Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany., Metzger CD; German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research (IKND), Otto-von-Guericke University, Magdeburg, Germany.; Department of Psychiatry and Psychotherapy, Otto-von-Guericke University, Magdeburg, Germany., Munk MH; Section for Dementia Research, Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany.; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany., Perneczky R; Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University Munich, München, Germany.; German Center for Neurodegenerative Diseases (DZNE, Munich), Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy) Munich, Munich, Germany.; Ageing Epidemiology Research Unit (AGE), School of Public Health, Imperial College London, London, UK., Peters O; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin, Berlin, Germany.; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany., Priller J; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Department of Psychiatry and Psychotherapy, Charité, Berlin, Germany., Rauchmann BS; Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University Munich, München, Germany., Roy N; German Center for Neurodegenerative Diseases, Bonn, Germany., Schneider A; German Center for Neurodegenerative Diseases, Bonn, Germany.; Department of Neurodegeneration and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany., Spottke A; German Center for Neurodegenerative Diseases, Bonn, Germany.; Department of Neurology, University of Bonn, Bonn, Germany., Spruth EJ; German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.; Department of Psychiatry and Psychotherapy, Charité, Berlin, Germany., Teipel S; German Center for Neurodegenerative Diseases (DZNE), Rostock, Germany.; Department of Psychosomatic Medicine, Rostock University Medical Center, Rostock, Germany., Tscheuschler M; Department of Psychiatry, Medical Faculty, University of Cologne, Cologne, Germany., Wagner M; German Center for Neurodegenerative Diseases, Bonn, Germany.; Department of Neurodegeneration and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany., Wiltfang J; Department for Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany.; German Center for Neurodegenerative Diseases (DZNE), Göttingen, Germany.; Department of Medical Sciences, Neurosciences and Signaling Group, Institute of Biomedicine (iBiMED), University of Aveiro, Aveiro, Portugal., Düzel E; German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.; Institute of Cognitive Neurology and Dementia Research (IKND), Otto-von-Guericke University, Magdeburg, Germany., Jessen F; German Center for Neurodegenerative Diseases, Bonn, Germany.; Department of Psychiatry, Medical Faculty, University of Cologne, Cologne, Germany.; Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Köln, Germany., Rizzoli SO; Department of Neuro- and Sensory Physiology, University Medical Center Göttingen, Göttingen, Germany.; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), University of Göttingen, Göttingen, Germany., Zimmermann WH; Institute of Pharmacology and Toxicology, University Medical Center Göttingen, Göttingen, Germany.; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), University of Göttingen, Göttingen, Germany.; DZKH (German Center for Cardiovascular Diseases), Göttingen, Germany., Schulze TG; Department for Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany.; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, Ludwig-Maximilians-University Munich, Munich, Germany.; Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University Munich, München, Germany., Falkai P; Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University Munich, München, Germany., Sananbenesi F; Department for Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany.; Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University Munich, München, Germany.; German Center for Neurodegenerative Diseases, Research Group for Genome Dynamics in Brain Diseases, Göttingen, Germany., Fischer A; Department for Epigenetics and Systems Medicine in Neurodegenerative Diseases, German Center for Neurodegenerative Diseases, Göttingen, Germany.; Department for Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany.; German Center for Neurodegenerative Diseases, Bonn, Germany.; German Center for Neurodegenerative Diseases (DZNE), Göttingen, Germany.; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), University of Göttingen, Göttingen, Germany.

Publikováno v: EMBO molecular medicine [EMBO Mol Med] 2021 Nov 08; Vol. 13 (11), pp. e13659. Date of Electronic Publication: 2021 Oct 11.

Changes in m6A RNA methylation contribute to heart failure progression by modulating translation.

Autor: Berulava T; Department for Epigenetics and Systems Medicine in Neurodegenerative Diseases, German Center for Neurodegenerative Diseases (DZNE), Göttingen, Germany., Buchholz E; Clinic for Cardiology and Pneumology, University Medical Center, Göttingen, Germany.; German Centre for Cardiovascular Research (DZHK), partner site Göttingen, Göttingen, Germany., Elerdashvili V; Department for Epigenetics and Systems Medicine in Neurodegenerative Diseases, German Center for Neurodegenerative Diseases (DZNE), Göttingen, Germany.; Bioinformatics Unit, German Center for Neurodegenerative Diseases (DZNE), Göttingen, Germany., Pena T; Department for Epigenetics and Systems Medicine in Neurodegenerative Diseases, German Center for Neurodegenerative Diseases (DZNE), Göttingen, Germany.; Bioinformatics Unit, German Center for Neurodegenerative Diseases (DZNE), Göttingen, Germany., Islam MR; Department for Epigenetics and Systems Medicine in Neurodegenerative Diseases, German Center for Neurodegenerative Diseases (DZNE), Göttingen, Germany., Lbik D; Clinic for Cardiology and Pneumology, University Medical Center, Göttingen, Germany.; German Centre for Cardiovascular Research (DZHK), partner site Göttingen, Göttingen, Germany., Mohamed BA; Clinic for Cardiology and Pneumology, University Medical Center, Göttingen, Germany.; German Centre for Cardiovascular Research (DZHK), partner site Göttingen, Göttingen, Germany., Renner A; Clinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Centre NRW, Ruhr-University Bochum, Bochum, Germany., von Lewinski D; Department of Cardiology, Medical University Graz, Graz, Austria., Sacherer M; Department of Cardiology, Medical University Graz, Graz, Austria., Bohnsack KE; Department of Molecular Biology, University Medical Center, Göttingen, Germany., Bohnsack MT; Department of Molecular Biology, University Medical Center, Göttingen, Germany., Jain G; Department for Epigenetics and Systems Medicine in Neurodegenerative Diseases, German Center for Neurodegenerative Diseases (DZNE), Göttingen, Germany.; Bioinformatics Unit, German Center for Neurodegenerative Diseases (DZNE), Göttingen, Germany., Capece V; Department for Epigenetics and Systems Medicine in Neurodegenerative Diseases, German Center for Neurodegenerative Diseases (DZNE), Göttingen, Germany., Cleve N; Department for Epigenetics and Systems Medicine in Neurodegenerative Diseases, German Center for Neurodegenerative Diseases (DZNE), Göttingen, Germany., Burkhardt S; Department for Epigenetics and Systems Medicine in Neurodegenerative Diseases, German Center for Neurodegenerative Diseases (DZNE), Göttingen, Germany., Hasenfuss G; Clinic for Cardiology and Pneumology, University Medical Center, Göttingen, Germany.; German Centre for Cardiovascular Research (DZHK), partner site Göttingen, Göttingen, Germany., Fischer A; Department for Epigenetics and Systems Medicine in Neurodegenerative Diseases, German Center for Neurodegenerative Diseases (DZNE), Göttingen, Germany.; Department of Psychiatry and Psychotherapy, University Medical Center, Göttingen, Germany.; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), University of Göttingen, Germany., Toischer K; Clinic for Cardiology and Pneumology, University Medical Center, Göttingen, Germany.; German Centre for Cardiovascular Research (DZHK), partner site Göttingen, Göttingen, Germany.

Publikováno v: European journal of heart failure [Eur J Heart Fail] 2020 Jan; Vol. 22 (1), pp. 54-66. Date of Electronic Publication: 2019 Dec 17.

m⁶ A 甲基化在心肌梗死后心肌重构发病机制中的研究进展.

Autor: 解长旭^1,2 xiechangxumail@163.com, 郭帅杰^1,2, 陈思琪^1,2, 张 蕾^1,2, 刘卫红^1,2, 李思耐^1,2, 周明学^1,2 mingxue78@163.com

Publikováno v: Chinese Journal of Arteriosclerosis. Jul2024, Vol. 32 Issue 7, p613-620. 8p.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Altered m6A RNA methylation governs denervation-induced muscle atrophy by regulating ubiquitin proteasome pathway.

Autor: Sun, Junjie¹ (AUTHOR), Zhou, Hai² (AUTHOR), Chen, Zehao¹ (AUTHOR), Zhang, Han³ (AUTHOR), Cao, Yanzhe¹ (AUTHOR), Yao, Xinlei¹ (AUTHOR), Chen, Xin⁴ (AUTHOR), Liu, Boya¹ (AUTHOR), Gao, Zihui¹ (AUTHOR), Shen, Yuntian¹ (AUTHOR) syt517@ntu.edu.cn, Qi, Lei⁵ (AUTHOR) qilei723@ntu.edu.cn, Sun, Hualin¹ (AUTHOR) sunhl@ntu.edu.cn

Publikováno v: Journal of Translational Medicine. 11/23/2023, Vol. 21 Issue 1, p1-17. 17p.