Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Eleonore Haltner-Ukomadu"'
Autor:
Eleonore Haltner-Ukomadu, Svitlana Gureyeva, Oleksii Burmaka, Andriy Goy, Lutz Mueller, Grygorii Kostyuk, Victor Margitich
Publikováno v:
Scientia Pharmaceutica, Vol 86, Iss 1, p 3 (2018)
An investigation into the biopharmaceutics classification and a study of the in vitro bioavailability (permeability and solubility) of the antiviral compound enisamium iodide (4-(benzylcarbamoyl)-1-methylpyridinium iodide) were carried out. The solub
Externí odkaz:
https://doaj.org/article/aa8a88dce0c7441da1070f99cb5751cc
Publikováno v:
Biopharmaceutics & Drug Disposition
Purpose Topical nonsteroidal anti‐inflammatory drug formulations are used commonly to treat musculoskeletal pain and inflammation. Drug properties and formulation composition are the primary determinants of the transdermal drug delivery rate. The e
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 111, Iss, Pp 785-790 (2019)
Topical formulations of non-steroidal anti-inflammatory drugs are often used to provide effective local drug concentration while limiting systemic exposure and associated adverse events. Formulation composition has great influence on the rate of tran
Autor:
Oleksii Burmaka, Svitlana Gureyeva, Andriy Goy, Eleonore Haltner-Ukomadu, Lutz Mueller, Grygorii Kostyuk, Victor Margitich
Publikováno v:
Scientia Pharmaceutica; Volume 86; Issue 1; Pages: 3
Scientia Pharmaceutica
Scientia Pharmaceutica, Vol 86, Iss 1, p 3 (2018)
Scientia Pharmaceutica
Scientia Pharmaceutica, Vol 86, Iss 1, p 3 (2018)
An investigation into the biopharmaceutics classification and a study of the in vitro bioavailability (permeability and solubility) of the antiviral compound enisamium iodide (4-(benzylcarbamoyl)-1-methylpyridinium iodide) were carried out. The solub
Autor:
Sascha Tillmanns, Beatrice Trammer, Petra Högger, Manfred Keller, Annette Amann, Eleonore Haltner-Ukomadu
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 70:758-764
Aerolized cyclosporine A (CsA) has been successfully used for prevention of organ rejection in lung transplant recipients. Various formulations of CsA are available and so far no direct comparison of their pharmacokinetics has been performed. Since c
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 68:390-399
The objective of this study was to establish and validate an ex vivo human cervical tissue model appropriate for transport studies of molecular and especially nucleic acid based drugs. For that purpose conditions had to be established for a standardi
Autor:
Udo Bock, Klaus-Jurgen Steffens, Andreas Nixdorf, Mohamed Tawfik Jalal, Eleonore Haltner-Ukomadu
Publikováno v:
Nachrichten aus der Chemie. 53:917-920
In der fruhen Phase der Arzneimittelentwicklung mit einer grosen Zahl an Wirkstoffkandidaten sind schnelle Analysenmethoden gefragt. Hier hat sich die LC-MS/MS-Kopplung durchgesetzt. Allerdings muss die Methodenentwicklung Effekte der Probenmatrix be
Autor:
Peter Meiers, Monika Kaca, Udo Bock, Eleonore Haltner-Ukomadu, Ulrich F. Schaefer, Claus-Michael Lehr, Frank Netzlaff
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 66(1)
The objective of this work was to compare the barrier function of the small diameter reconstructed human epidermis model Episkin (d=12 mm) to human skin in vitro. For that purpose a modification for the Franz diffusion cell (d=15mm) had to be develop
Autor:
Thomas E. Mürdter, Ulrich F. Schaefer, Elke Kleideiter, Eleonore Haltner-Ukomadu, Christiane Baldes, J. Mueller, Ulrich Klotz, Udo Bock, Kamilla Piotrowska, Claus-Michael Lehr, Hanno Huwer, Sebastian Taetz
Publikováno v:
Pharmaceutical research. 23(5)
To characterize the telomerase inhibitor and G-quadruplex stabilizing substance 9-[4-(N,N-dimethylamino)phenylamino]-3,6-bis (3-pyrrolodino-propionamido) acridine x 3HCl (BRACO19) in terms of biopharmaceutical properties such as solubility, protein b
Autor:
Hans-Udo Krächter, Walter Diembeck, Silke Kersen, Hans-Jürgen Düsing, Alexander Vuia, Christine Hoffmann, Annette Mehling, Monika Schäfer-Korting, Manfred Kietzmann, Claus-Michael Lehr, Eleonore Haltner-Ukomadu, Udo Bock, Hans Christian Korting, Monika Kaca, Horst Spielmann, Elisabeth Schmidt, Hennicke Kamp, A.O. Gamer, Frank Niedorf, Frank Netzlaff, Manfred Liebsch, Michaela Weimer, S. Schreiber, M.K. Rübbelke, Christel C. Müller-Goymann, Ulrich Schäfer
Publikováno v:
Scopus-Elsevier
A formal validation study was performed, in order to investigate whether the commercially-available reconstructed human epidermis (RHE) models, EPISKIN®, EpiDerm™ and SkinEthic®, are suitable for in vitro skin absorption testing. The skin types c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a51577b89c2c18b40e2b31f5345661b
http://www.scopus.com/inward/record.url?eid=2-s2.0-45549105564&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-45549105564&partnerID=MN8TOARS