Prevalence of 185delAG and 5382insC mutations in BRCA1, and 6174delT in BRCA2 in women of Ashkenazi Jewish origin in southern Brazil

Autor: Isabel Cristina Bandeira, Sandra Leistner-Segal, Eleonora Souza Dias, Taiana Valente Tubino, Luciana Grazziotin Rossato, Ana Cristina da Costa Bittelbrunn, Criste Vignol Dillenburg

Publikováno v: Genetics and Molecular Biology, Volume: 35, Issue: 3, Pages: 599-602, Published: 2012
Genetics and Molecular Biology
ResearcherID
Genetics and Molecular Biology v.35 n.3 2012
Sociedade Brasileira de Genética (SBG)
instacron:SBG
Genetics and Molecular Biology, Vol 35, Iss 3, Pp 599-602 (2012)
Repositório Institucional da UFRGS
Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS

Certain mutations in BRCA1 and BRCA2 genes are frequent in the Ashkenazi Jewish population. Several factors contribute to this increased frequency, including consanguineous marriages and an event known as a "bottleneck", which occurred in the past an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e9ee6e2d15b6d64e9a6ec63fdf4f184
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572012000400009&lng=en&tlng=en