Výsledky vyhledávání - "Eleonora Petrucci"

Akademický článek

Ovarian Cancers: Genetic Abnormalities, Tumor Heterogeneity and Progression, Clonal Evolution and Cancer Stem Cells

Autor: Ugo Testa, Eleonora Petrucci, Luca Pasquini, Germana Castelli, Elvira Pelosi

Publikováno v: Medicines, Vol 5, Iss 1, p 16 (2018)

Four main histological subtypes of ovarian cancer exist: serous (the most frequent), endometrioid, mucinous and clear cell; in each subtype, low and high grade. The large majority of ovarian cancers are diagnosed as high-grade serous ovarian cancers

Externí odkaz: https://doaj.org/article/dfcc4d11d5204fd2a03612f1d307f7cd

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Akademický článek

A small molecule SMAC mimic LBW242 potentiates TRAIL- and anticancer drug-mediated cell death of ovarian cancer cells.

Autor: Eleonora Petrucci, Luca Pasquini, Manuela Bernabei, Ernestina Saulle, Mauro Biffoni, Fabio Accarpio, Simone Sibio, Angelo Di Giorgio, Violante Di Donato, Assunta Casorelli, Pierluigi Benedetti-Panici, Ugo Testa

Publikováno v: PLoS ONE, Vol 7, Iss 4, p e35073 (2012)

BACKGROUND: Ovarian cancer remains a leading cause of death in women and development of new therapies is essential. Second mitochondria derived activator of caspase (SMAC) has been described to sensitize for apoptosis. We have explored the pro-apopto

Externí odkaz: https://doaj.org/article/fb7f06b3a0f84d43ab66e7d88134c29e

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Akademický článek

Mechanism of human Hb switching: a possible role of the kit receptor/miR 221-222 complex

Autor: Marco Gabbianelli, Ugo Testa, Ornella Morsilli, Elvira Pelosi, Ernestina Saulle, Eleonora Petrucci, Germana Castelli, Serena Giovinazzi, Gualtiero Mariani, Micol E. Fiori, Giuseppina Bonanno, Adriana Massa, Carlo M. Croce, Laura Fontana, Cesare Peschle

Publikováno v: Haematologica, Vol 95, Iss 8 (2010)

Background The human hemoglobin switch (HbF→HbA) takes place in the peri/post-natal period. In adult life, however, the residual HbF (

Externí odkaz: https://doaj.org/article/6413d18974c34a93bebccc34cd5d711a

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Assessment of Tumor Heterogeneity in High-Grade Serous Ovarian Cancer: Mass Cytometry to Understand the Complex Tumor Biology

Autor: Luca, Pasquini, Roberta, Riccioni, Eleonora, Petrucci

Publikováno v: Methods in molecular biology (Clifton, N.J.). 2535

Ovarian cancer (OC) is the most deadly gynecological malignancy worldwide. OC patients undergo debulking surgery followed by platinum/taxane-based chemotherapy; however, despite recent development of new therapeutic approaches based on combination of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1527e0f28e80072875b72623ae615b6c
https://pubmed.ncbi.nlm.nih.gov/35867226

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Isolation and preliminary characterization of a human 'phage display'-derived antibody against neural adhesion molecule-1 antigen interfering with fibroblast growth factor receptor-1 binding

Autor: Maria Luisa Dupuis, Alessandra Boe, Mauro Andreotti, Carla Raggi, Mara Gellini, Alessandra Mallano, Alessandro Ascione, Eleonora Petrucci, Gianni Colotti, Stefano Barca, Stefano Vella, Roberta Riccioni, Michela Flego

Publikováno v: Human antibodies 29 (2021): 63–84. doi:10.3233/HAB-200431
info:cnr-pdr/source/autori:Flego M.; Colotti G.; Ascione A.; Dupuis M.L.; Petrucci E.; Riccioni R.; Andreotti M.; Raggi C.; Boe A.; Barca S.; Gellini M.; Vella S.; Mallano A./titolo:Isolation and preliminary characterization of a human 'phage display'-derived antibody against neural adhesion molecule-1 antigen interfering with fibroblast growth factor receptor-1 binding/doi:10.3233%2FHAB-200431/rivista:Human antibodies/anno:2021/pagina_da:63/pagina_a:84/intervallo_pagine:63–84/volume:29

BACKGROUND: The NCAM or CD56 antigen is a cell surface glycoprotein belonging to the immunoglobulin super-family involved in cell-cell and cell-matrix adhesion. NCAM is also over-expressed in many tumour types and is considered a tumour associated an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69121e4b14ab6d503ce0a5694b5bbd94
https://pubmed.ncbi.nlm.nih.gov/33164927

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qSNE: quadratic rate t-SNE optimizer with automatic parameter tuning for large datasets

Autor: Eleonora Petrucci, Katja Kaipio, Juha Koiranen, Oskari Lehtonen, Antti Häkkinen, Luca Pasquini, Olli Carpén, Sakari Hietanen, Johanna Hynninen, Rainer Lehtonen, Mauro Biffoni, Julia Casado, Sampsa Hautaniemi

Publikováno v: Bioinformatics

Motivation Non-parametric dimensionality reduction techniques, such as t-distributed stochastic neighbor embedding (t-SNE), are the most frequently used methods in the exploratory analysis of single-cell datasets. Current implementations scale poorly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04808ad52b65a0a010e99c4fc0d8fe7c
http://hdl.handle.net/10138/325933

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Correction: Inhibition of TPO-induced MEK or mTOR activity induces opposite effects on the ploidy of human differentiating megakaryocytes (doi:10.1242/jcs.02784)

Autor: R Guerriero, Isabella Parolini, Ugo Testa, Cesare Peschle, Eleonora Petrucci, Paola Samoggia, C Chelucci, Marco Gabbianelli, Massimo Sargiacomo

Publikováno v: Journal of Cell Science. 132

This Expression of Concern relates to [J. Cell Sci. (2006) 119, 744-752 (doi:10.1242/jcs.02784)][1]. Journal of Cell Science was informed that several bands in each of the ERK1/2, P-AKT, AKT and p70S6K blots in Fig. 5 look very similar. After discuss

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::125ed0f50df191e10a54e7285f685f07
https://doi.org/10.1242/jcs.233676

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Hemopoietic and angiogenetic progenitors in healthy athletes: different responses to endurance and maximal exercise

Autor: Veca M, Ugo Testa, Eleonora Petrucci, Giuseppe Morici, Laura Chimenti, Paolo Palange, Gioia M, Maria R. Bonsignore, Alice Huertas, Anna Bonanno, Roberta Riccioni, Gualtiero Mariani

Publikováno v: Journal of Applied Physiology. 109:60-67

J Appl Physiol. 2010 Jul;109(1):60-7. Epub 2010 May 6. Hemopoietic and angiogenetic progenitors in healthy athletes: different responses to endurance and maximal exercise. Bonsignore MR, Morici G, Riccioni R, Huertas A, Petrucci E, Veca M, Mariani G,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c5e64859caa771b47ba62cf16dc476d
https://doi.org/10.1152/japplphysiol.01344.2009

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