Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Eleonora Lapi"'
Autor:
Catarina P. Santos, Eleonora Lapi, Jaime Martínez de Villarreal, Laura Álvaro-Espinosa, Asunción Fernández-Barral, Antonio Barbáchano, Orlando Domínguez, Ashley M. Laughney, Diego Megías, Alberto Muñoz, Francisco X. Real
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
The biology of the urothelium has been difficult to study given the lack of methods to propagate these cells. Here, the authors generate mouse urothelial organoids derived from bladder urothelial cells with high CD49f/ITGA6 and define what regulates
Externí odkaz:
https://doaj.org/article/320d107785b94de1b92b9124a3eed2a2
Autor:
Magali De Koninck, Eleonora Lapi, Claudio Badía-Careaga, Itziar Cossío, Daniel Giménez-Llorente, Miriam Rodríguez-Corsino, Elena Andrada, Andrés Hidalgo, Miguel Manzanares, Francisco X. Real, Ana Losada
Publikováno v:
Cell Reports, Vol 32, Iss 6, Pp 108014- (2020)
Summary: Cohesin mediates sister chromatid cohesion and 3D genome folding. Two versions of the complex carrying STAG1 or STAG2 coexist in somatic vertebrate cells. STAG2 is commonly mutated in cancer, and germline mutations have been identified in co
Externí odkaz:
https://doaj.org/article/4fc2b6de40da498d9e73ce3ab9b6fc0f
Autor:
A. Fernández-Barral, Catarina P. Santos, Orlando Domínguez, Alberto Muñoz, Francisco X. Real, Diego Megías, Laura Alvaro-Espinosa, Antonio Barbáchano, Eleonora Lapi, Ashley M. Laughney, Jaime Martinez de Villarreal
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
Recercat. Dipósit de la Recerca de Catalunya
Repisalud
Instituto de Salud Carlos III (ISCIII)
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
Recercat. Dipósit de la Recerca de Catalunya
Repisalud
Instituto de Salud Carlos III (ISCIII)
© The Author(s) 2019.
Understanding urothelial stem cell biology and differentiation has been limited by the lack of methods for their unlimited propagation. Here, we establish mouse urothelial organoids that can be maintained uninterruptedly f
Understanding urothelial stem cell biology and differentiation has been limited by the lack of methods for their unlimited propagation. Here, we establish mouse urothelial organoids that can be maintained uninterruptedly f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce9301b90c22466014a684005590dc86
https://doaj.org/article/320d107785b94de1b92b9124a3eed2a2
https://doaj.org/article/320d107785b94de1b92b9124a3eed2a2
Autor:
Yasmina Cuartero, Alfonso Valencia, F. Radvanyi, Vera Pancaldi, Marc A. Marti-Renom, Miguel Madrid-Mencía, Enrique Carrillo-de-Santa Pau, Francisco X. Real, François Serra, Juan Antonio Rodríguez, Eleonora Lapi, Hélène Neyret-Kahn, François Le Dily, Mirabai Cuenca-Ardura, Laia Richart
Publikováno v:
Repisalud
Instituto de Salud Carlos III (ISCIII)
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2021, ⟨10.1093/nar/gkab864⟩
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
Instituto de Salud Carlos III (ISCIII)
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2021, ⟨10.1093/nar/gkab864⟩
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
Cohesin exists in two variants containing STAG1 or STAG2. STAG2 is one of the most mutated genes in cancer and a major bladder tumor suppressor. Little is known about how its inactivation contributes to tumorigenesis. Here, we analyze the genomic dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::284738d186c887ef6a9c316a8a876eaa
http://hdl.handle.net/10230/52354
http://hdl.handle.net/10230/52354
Autor:
Mirabai Cuenca, Marc A. Marti-Renom, Yasmina Cuartero, François Le Dily, Alfonso Valencia, Francisco X. Real, François Serra, Enrique Carrillo-de-Santa Pau, Juan Antonio Rodríguez, Laia Richart, Eleonora Lapi, Hélène Neyret-Kahn, Miguel Madrid-Mencía, F. Radvanyi, Vera Pancaldi
Cohesin exists in two variants, containing either STAG1 or STAG2. STAG2 is one of the most commonly mutated genes in human cancer, and a major bladder cancer tumor suppressor. Little is known about how its inactivation contributes to tumor developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3db6b96ea520fdf867e97d09d84a4ccc
https://doi.org/10.1101/2020.08.06.240457
https://doi.org/10.1101/2020.08.06.240457
Autor:
Miriam Rodríguez-Corsino, Ana Losada, Daniel Giménez-Llorente, Andrés Hidalgo, Francisco X. Real, Claudio Badia-Careaga, Magali De Koninck, Itziar Cossío, Miguel Manzanares, Elena Andrada, Eleonora Lapi
Publikováno v:
Cell Reports, Vol 32, Iss 6, Pp 108014-(2020)
Repisalud
Instituto de Salud Carlos III (ISCIII)
Digital.CSIC. Repositorio Institucional del CSIC
Universitat Politècnica de Catalunya (UPC)
Repisalud
Instituto de Salud Carlos III (ISCIII)
Digital.CSIC. Repositorio Institucional del CSIC
Universitat Politècnica de Catalunya (UPC)
Cohesin mediates sister chromatid cohesion and 3D genome folding. Two versions of the complex carrying STAG1 or STAG2 coexist in somatic vertebrate cells. STAG2 is commonly mutated in cancer, and germline mutations have been identified in cohesinopat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6887edec5316d0c5cf72f6c6f450ab34
http://www.sciencedirect.com/science/article/pii/S2211124720309992
http://www.sciencedirect.com/science/article/pii/S2211124720309992
Autor:
Catarina P. Santos, Eleonora Lapi, Antonio Barbáchano, Alberto Muñoz, A. Fernández-Barral, Francisco X. Real
Here we describe the establishment of mouse urothelial organoids from healthy urothelial tissue digests. NMU-o can grow within 7 days in medium enriched in growth factors, without FACS-sorting epithelial populations and can be passaged in culture for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f0ef2d2e52d39a7f06234dadc155879
https://doi.org/10.21203/rs.2.12413/v1
https://doi.org/10.21203/rs.2.12413/v1
Autor:
Eleonora Lapi, Mattias Höglund, Lars Dyrskjøt, Ana Losada, Villareal J Martínez de, Francisco X. Real, Catarina P. Santos, M Kalisz, Gottfrid Sjödahl
Publikováno v:
Urologic Oncology: Seminars and Original Investigations. 38:896
Introduction Several groups, including ours, have identified STAG2 as a new bladder tumor suppressor gene. STAG2 is part of cohesin, a complex involved in chromosome segregation, DNA repair and chromatin organization. A role for STAG2 in hematopoieti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74c42440ac706c8b3342b58d7334c85e
https://doi.org/10.1016/j.urolonc.2020.10.022
https://doi.org/10.1016/j.urolonc.2020.10.022
Autor:
Antonio Barbáchano, Diego Megías, Catarina P. Santos, Eleonora Lapi, Laura Alvaro-Espinosa, Alberto Muñoz, Francisco X. Real, A. Fernández-Barral
SummaryThe urothelium is a specialized stratified epithelium with unique structural and functional features. Understanding the mechanisms involved in urothelial stem cell biology and differentiation has been limited by the lack of methods for unlimit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d77a26961a32f19c52cb6874c6e0d80c
Autor:
Eleonora Lapi, Antonio Barbáchano, Francisco X. Real, Laura Álvaro, Alberto Muñoz, Catarina P. Santos, Asunción Barral
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Resumen del póster presentado al 15th Meeting of the International Bladder Cancer Network (IBCN), celebrado en Lisboa (Portugal) del 21 al 23 de octubre de 2017.
[Objectives]: Urothelial bladder cancer (UBC) is a heterogeneous disease. Currentl
[Objectives]: Urothelial bladder cancer (UBC) is a heterogeneous disease. Currentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a5b4150da52584dd0d3908bad0ce846
http://hdl.handle.net/10261/189610
http://hdl.handle.net/10261/189610