Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Eleonora Khlebus"'
Autor:
Eleonora Khlebus, Vladimir Kutsenko, Alexey Meshkov, Alexandra Ershova, Anna Kiseleva, Anton Shevtsov, Natalia Shcherbakova, Anastasiia Zharikova, Vadim Lankin, Alla Tikhaze, Irina Chazova, Elena Yarovaya, Oksana Drapkina, Sergey Boytsov
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0217620 (2019)
Oxidatively modified low-density lipoproteins (oxLDL) play an important role in the occurrence and progression of atherosclerosis. To identify the genetic factors influencing the oxLDL levels, we have genotyped 776 DNA samples of Russian individuals
Externí odkaz:
https://doaj.org/article/0730e84079ac42d8985efca0a02fcebf
Autor:
Eleonora Khlebus, Veena K. Vuttaradhi, Thomas Welte, Namrata Khurana, Joseph Celestino, Hannah C. Beird, Curtis Gumbs, Latasha Little, Alejandra Flores Legarreta, Bryan M. Fellman, Tri Nguyen, Barrett Lawson, Sammy Ferri-Borgogno, Samuel C. Mok, Russell R. Broaddus, David M. Gershenson, P. Andrew Futreal, R. Tyler Hillman
Publikováno v:
Molecular Cancer Research. 21:483-494
Adult-type granulosa cell tumors (aGCT) are rare ovarian sex cord tumors with few effective treatments for recurrent disease. The objective of this study was to characterize the tumor microenvironment (TME) of primary and recurrent aGCTs and to ident
Autor:
R. Tyler Hillman, P. Andrew Futreal, David M. Gershenson, Russell R. Broaddus, Samuel C. Mok, Sammy Ferri-Borgogno, Barrett Lawson, Tri Nguyen, Bryan M. Fellman, Alejandra Flores Legarreta, Latasha Little, Curtis Gumbs, Hannah C. Beird, Joseph Celestino, Namrata Khurana, Thomas Welte, Veena K. Vuttaradhi, Eleonora Khlebus
RNA Sequencing QC Metrics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46943888c66a7d69d57cd0cbf4fef713
https://doi.org/10.1158/1541-7786.22725314
https://doi.org/10.1158/1541-7786.22725314
Autor:
R. Tyler Hillman, P. Andrew Futreal, David M. Gershenson, Russell R. Broaddus, Samuel C. Mok, Sammy Ferri-Borgogno, Barrett Lawson, Tri Nguyen, Bryan M. Fellman, Alejandra Flores Legarreta, Latasha Little, Curtis Gumbs, Hannah C. Beird, Joseph Celestino, Namrata Khurana, Thomas Welte, Veena K. Vuttaradhi, Eleonora Khlebus
Adult-type granulosa cell tumors (aGCT) are rare ovarian sex cord tumors with few effective treatments for recurrent disease. The objective of this study was to characterize the tumor microenvironment (TME) of primary and recurrent aGCTs and to ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72617fb515f528475ebcabb0c455fea0
https://doi.org/10.1158/1541-7786.c.6603389.v2
https://doi.org/10.1158/1541-7786.c.6603389.v2
Autor:
R. Tyler Hillman, P. Andrew Futreal, David M. Gershenson, Russell R. Broaddus, Samuel C. Mok, Sammy Ferri-Borgogno, Barrett Lawson, Tri Nguyen, Bryan M. Fellman, Alejandra Flores Legarreta, Latasha Little, Curtis Gumbs, Hannah C. Beird, Joseph Celestino, Namrata Khurana, Thomas Welte, Veena K. Vuttaradhi, Eleonora Khlebus
S1. Heatmap of unsupervised hierarchical clustering of the top 1000 most variable genes.S2. Violin plots showing the expression levels of genes previously identified as differentially expressed genes between primary and recurrent tumors in Haltia et
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a228780cf7ee879c5515dc478d40f5f
https://doi.org/10.1158/1541-7786.22647020.v1
https://doi.org/10.1158/1541-7786.22647020.v1
Autor:
Veena Vuttaradhi, Eleonora Khlebus, Thomas Welte, Namrata Khurana, Barrett Lawson, Robert Tyler Hillman
Publikováno v:
Cancer Research. 83:1462-1462
Background: A missense mutation in the Forkhead domain-containing FOXL2 (Foxl2 p.C134W) transcription factor is found in nearly all adult-type granulosa cell tumors, but the oncogenic mechanism of this mutation is not known. Other Forkhead family tra
Autor:
Eleonora Khlebus, Veena K. Vuttaradhi, Thomas Welte, Namrata Khurana, Joseph Celestino, Hannah C. Beird, Curtis Gumbs, Latasha Little, Alejandra Flores Legarreta, Tri Nguyen, Barrett Lawson, Russell R. Broaddus, David M. Gershenson, P. Andrew Futreal, R. Tyler Hillman
Publikováno v:
Cancer Research. 83:2503-2503
Background: Adult-type granulosa cell tumors (AGCT) are rare ovarian sex cord tumors that exhibit near-universal FOXL2 c.C402G (p.Cys134Trp) hotspot mutations. AGCT recurrence is difficult to predict and is almost always incurable after relapse. Litt
Autor:
Thomas Welte, Veena Vuttaradhi, Eleonora Khlebus, Barrett Lawson, Robert T. Hillman, Nghi Nguyen, Mary Sobieski, Reid T. Powell, Clifford Stephan
Publikováno v:
Cancer Research. 83:453-453
Background: Nearly all adult-type granulosa cell tumors of the ovary (aGCTs) carry the same oncogenic mutation affecting the second winged helix domain of the Forkhead family transcription factor FOXL2 (c.C402G; p.C134W). There are no currently avail
Autor:
A. V. Kiseleva, Petr Slominsky, Olga V. Kurilova, Alexey N Meshkov, Irina A. Efimova, Eleonora Khlebus, Svetlana A. Shalnova, A. I. Ershova, Olga P Skirko, M. V. Klimushina, Mikhail G. Divashuk, Oxana Drapkina, Anastasia Zharikova, Evgeniia Sotnikova, Maria S. Pokrovskaya
Publikováno v:
Pharmacogenomics and Personalized Medicine. 13:679-686
Purpose Cystic fibrosis (CF) is one of the most common monogenic diseases with an autosomal recessive inheritance. Carrier screening leads to a reduction in the number of children born with CF disease. The aim of this study was to develop the custom
Autor:
Eleonora Khlebus, Veena K. Vuttaradhi, Thomas Welte, Namrata Khurana, Joseph Celestino, Hannah C. Beird, Curtis Gumbs, Latasha Little, Tri Nguyen, Barrett Lawson, Russell R. Broaddus, David M. Gershenson, Andrew Futreal, R. Tyler Hillman
Publikováno v:
Leading Edge of Cancer Research Symposium: Poster Session.