Zobrazeno 1 - 10 of 68 pro vyhledávání: '"Eleonora Katz"'
1
Functional postnatal maturation of the medial olivocochlear efferent-outer hair cell synapse
Autor: Ana Belén Elgoyhen, Eleonora Katz, Lucas G. Vattino, Carolina Wedemeyer
Publikováno v: J Neurosci
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
The organ of Corti, the auditory mammalian sensory epithelium, contains two types of mechanotransducer cells, inner and outer hair cells (IHCs and OHCs, respectively). IHCs are involved in conveying acoustic stimuli to the central nervous system whil
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::436f34cb18874ca5775ad753fb928754
http://www.jneurosci.org/lookup/doi/10.1523/JNEUROSCI.2409-19.2020
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2
A Gain-of-Function Mutation in the α9 Nicotinic Acetylcholine Receptor Alters Medial Olivocochlear Efferent Short-Term Synaptic Plasticity
Autor: Mariano N. Di Guilmi, Ana Belén Elgoyhen, Carolina Wedemeyer, Paul A. Fuchs, Jimena A. Ballestero, Stéphane F. Maison, Marcelo J. Moglie, Julián Taranda, Eleonora Katz, Lucas G. Vattino, M. Charles Liberman
Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Gain control of the auditory system operates at multiple levels. Cholinergic medial olivocochlear (MOC) fibers originate in the brainstem and make synaptic contacts at the base of the outer hair cells (OHCs), the final targets of several feedback loo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e3c3bef893ed97a63d16d0d446293f5
https://doi.org/10.1523/jneurosci.2528-17.2018
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3
Akademický článek
A point mutation in the hair cell nicotinic cholinergic receptor prolongs cochlear inhibition and enhances noise protection.
Autor: Julian Taranda, Stéphane F Maison, Jimena A Ballestero, Eleonora Katz, Jessica Savino, Douglas E Vetter, Jim Boulter, M Charles Liberman, Paul A Fuchs, A Belén Elgoyhen
Publikováno v: PLoS Biology, Vol 7, Iss 1, p e18 (2009)
The transduction of sound in the auditory periphery, the cochlea, is inhibited by efferent cholinergic neurons projecting from the brainstem and synapsing directly on mechanosensory hair cells. One fundamental question in auditory neuroscience is wha
Externí odkaz: https://doaj.org/article/fe6e8caadb304db3972a5af73403bdc9
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4
Developmental synaptic changes at the transient olivocochlear-inner hair cell synapse
Autor: Ana Belén Elgoyhen, Carolina Wedemeyer, Graciela Kearney, Eleonora Katz, Lucas G. Vattino, Javier Zorrilla de San Martin
Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
In the mature mammalian cochlea, inner hair cells (IHCs) are mainly innervated by afferent fibers that convey sound information to the CNS. During postnatal development, however, medial olivocochlear (MOC) efferent fibers transiently innervate the IH
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36284f9e135d3ce171e859453813ca79
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5
Tracking the Molecular Evolution of Calcium Permeability in a Nicotinic Acetylcholine Receptor
Autor: Marcela Lipovsek, Neil S. Millar, Angélica Fierro, Ana Belén Elgoyhen, Edwin G. Pérez, Juan Carlos Boffi, Eleonora Katz, Paul A. Fuchs
Publikováno v: Molecular Biology and Evolution
Nicotinic acetylcholine receptors are a family of ligand-gated nonselective cationic channels that participate in fundamental physiological processes at both the central and the peripheral nervous system. The extent of calcium entry through ligand-ga
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9945ab3da9ca47e850b0728bbe2a459
http://europepmc.org/articles/PMC4245820
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6
Activation of Presynaptic GABAB(1a,2)Receptors Inhibits Synaptic Transmission at Mammalian Inhibitory Cholinergic Olivocochlear–Hair Cell Synapses
Autor: Eleonora Katz, Ana Vanesa Torbidoni, Ana Belén Elgoyhen, Jimena A. Ballestero, Carolina Wedemeyer, Javier Zorrilla de San Martin, Paul A. Fuchs, María Eugenia Gómez-Casati, Bernhard Bettler
Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
The synapse between olivocochlear (OC) neurons and cochlear mechanosensory hair cells is cholinergic, fast, and inhibitory. The inhibitory sign of this cholinergic synapse is accounted for by the activation of Ca 2+ -permeable postsynaptic α9α10 ni
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b301dd083c345b112dade419a9196de9
https://doi.org/10.1523/jneurosci.2554-13.2013
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7
Positive modulation of the α9α10 nicotinic cholinergic receptor by ascorbic acid
Autor: Juan Carlos Boffi, Eleonora Katz, Carolina Wedemeyer, Marcela Lipovsek, Daniel Juan Calvo, Ana Belén Elgoyhen
Publikováno v: British Journal of Pharmacology. 168:954-965
Background and Purpose The activation of α9α10 nicotinic cholinergic receptors (nAChRs) present at the synapse between efferent olivocochlear fibres and cochlear hair cells can prevent acoustic trauma. Hence, pharmacological potentiators of these r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e74c9faaa601cf7afbf02aebfeb33b5f
https://doi.org/10.1111/j.1476-5381.2012.02221.x
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8
The efferent medial olivocochlear-hair cell synapse
Autor: Ana Belén Elgoyhen, Eleonora Katz
Publikováno v: Journal of Physiology-Paris. 106:47-56
Amplification of incoming sounds in the inner ear is modulated by an efferent pathway which travels back from the brain all the way to the cochlea. The medial olivocochlear system makes synaptic contacts with hair cells, where the neurotransmitter ac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8285028e757333262d9826a94920b08e
https://doi.org/10.1016/j.jphysparis.2011.06.001
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9
Ca2+and Ca2+-Activated K+Channels That Support and Modulate Transmitter Release at the Olivocochlear Efferent–Inner Hair Cell Synapse
Autor: Sonja Pyott, Jimena Ballestero, Eleonora Katz, Javier Zorrilla de San Martin
Publikováno v: The Journal of Neuroscience. 30:12157-12167
In the mammalian auditory system, the synapse between efferent olivocochlear (OC) neurons and sensory cochlear hair cells is cholinergic, fast, and inhibitory. This efferent synapse is mediated by the nicotinic α9α10 receptor coupled to the activat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e847d178f6b29bc0585da5a8f2441c5
https://doi.org/10.1523/jneurosci.2541-10.2010
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10
The nicotinic receptor of cochlear hair cells: A possible pharmacotherapeutic target?
Autor: Ana Belén Elgoyhen, Paul A. Fuchs, Eleonora Katz
Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Mechanosensory hair cells of the organ of Corti transmit information regarding sound to the central nervous system by way of peripheral afferent neurons. In return, the central nervous system provides feedback and modulates the afferent stream of inf
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bde423722e4a11b41148d16e4a8c572
https://doi.org/10.1016/j.bcp.2009.05.023
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