Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Eleonora Ciarlo"'
Autor:
Angelique Cercillieux, Joanna Ratajczak, Magali Joffraud, José Luis Sanchez-Garcia, Guillaume Jacot, Alix Zollinger, Sylviane Métairon, Judith Giroud-Gerbetant, Marie Rumpler, Eleonora Ciarlo, Miriam Valera-Alberni, Audrey Sambeat, Carles Canto
Publikováno v:
Molecular Metabolism, Vol 66, Iss , Pp 101605- (2022)
Objective: Disturbances in NAD+ metabolism have been described as a hallmark for multiple metabolic and age-related diseases, including type 2 diabetes. While alterations in pancreatic β-cell function are critical determinants of whole-body glucose
Externí odkaz:
https://doaj.org/article/945b64715a904374bce76583c128706e
Autor:
Charlotte Théroude, Marta Reverte, Tytti Heinonen, Eleonora Ciarlo, Irene T. Schrijver, Nikolaos Antonakos, Nicolas Maillard, Florian Pralong, Didier Le Roy, Thierry Roger
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Trained immunity refers to the ability of the innate immune system exposed to a first challenge to provide an enhanced response to a secondary homologous or heterologous challenge. We reported that training induced with β-glucan one week before infe
Externí odkaz:
https://doaj.org/article/2b5ed9c435204569ae3f45b8e9d027a1
Autor:
Raphaël Enaud, Renaud Prevel, Eleonora Ciarlo, Fabien Beaufils, Gregoire Wieërs, Benoit Guery, Laurence Delhaes
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
The gut and lungs are anatomically distinct, but potential anatomic communications and complex pathways involving their respective microbiota have reinforced the existence of a gut–lung axis (GLA). Compared to the better-studied gut microbiota, the
Externí odkaz:
https://doaj.org/article/bc2862b5bb6d4e80b362c6809b5d0a70
Autor:
Eleonora Ciarlo, Tytti Heinonen, Jérôme Lugrin, Hans Acha-Orbea, Didier Le Roy, Johan Auwerx, Thierry Roger
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Sirtuin 3 (SIRT3) is the main mitochondrial deacetylase. SIRT3 regulates cell metabolism and redox homeostasis, and protects from aging and age-associated pathologies. SIRT3 may drive both oncogenic and tumor-suppressive effects. SIRT3 defic
Externí odkaz:
https://doaj.org/article/bc479b495c564277aaaa4232ca0847e2
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Sirtuin 2 (SIRT2) and SIRT3 are cytoplasmic and mitochondrial NAD-dependent deacetylases. SIRT2 and SIRT3 target proteins involved in metabolic, proliferation and inflammation pathways and have been implicated in the pathogenesis of neurodegenerative
Externí odkaz:
https://doaj.org/article/c00dec5f985d45ad84d31ab91ee37ab6
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The sirtuins SIRT3 and SIRT5 are the main mitochondrial lysine deacetylase and desuccinylase, respectively. SIRT3 and SIRT5 regulate metabolism and redox homeostasis and have been involved in age-associated metabolic, neurologic and oncologic disease
Externí odkaz:
https://doaj.org/article/f47c12dd049841719cdaa15fc7b9bc89
Autor:
Tytti Heinonen, Eleonora Ciarlo, Charlotte Théroude, Aimilia Pelekanou, Jacobus Herderschee, Didier Le Roy, Thierry Roger
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Sirtuin 5 (SIRT5) is a member of the family of NAD+-dependent lysine/histone deacetylases. SIRT5 resides mainly in the mitochondria where it catalyzes deacetylation, demalonylation, desuccinylation, and deglutarylation of lysine to regulate metabolic
Externí odkaz:
https://doaj.org/article/c0cb66ed02f447b99cec68aae4889a49
Autor:
Eleonora Ciarlo, Tytti Heinonen, Charlotte Théroude, Jacobus Herderschee, Matteo Mombelli, Jérôme Lugrin, Marc Pfefferlé, Beatrice Tyrrell, Sarah Lensch, Hans Acha-Orbea, Didier Le Roy, Johan Auwerx, Thierry Roger
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Sirtuin 2 (SIRT2) is one of the seven members of the family of NAD+-dependent histone deacetylases. Sirtuins target histones and non-histone proteins according to their subcellular localization, influencing various biological processes. SIRT2 resides
Externí odkaz:
https://doaj.org/article/b0cfa00f1243495f8bf99759e3e50e8e
Autor:
Eleonora Ciarlo, Sara Massone, Ilaria Penna, Mario Nizzari, Arianna Gigoni, Giorgio Dieci, Claudio Russo, Tullio Florio, Ranieri Cancedda, Aldo Pagano
Publikováno v:
Disease Models & Mechanisms, Vol 6, Iss 2, Pp 424-433 (2013)
SUMMARY Recent studies indicated that sortilin-related receptor 1 (SORL1) is a risk gene for late-onset Alzheimer's disease (AD), although its role in the aetiology and/or progression of this disorder is not fully understood. Here, we report the find
Externí odkaz:
https://doaj.org/article/ce060c0f1dbf4dbd921ea90c750f34f1
Autor:
Silvia Ferreira Lopes, Gaëlle Vacher, Eleonora Ciarlo, Dessislava Savova-Bianchi, Thierry Roger, Hélène Niculita-Hirzel
Publikováno v:
Toxins, Vol 9, Iss 11, p 337 (2017)
The type B trichothecene mycotoxins deoxynivalenol (DON), nivalenol (NIV) and fusarenon-X (FX) are structurally related secondary metabolites frequently produced by Fusarium on wheat. Consequently, DON, NIV and FX contaminate wheat dusts, exposing gr
Externí odkaz:
https://doaj.org/article/5e4dfeb0c62e462797b15ea854a14430