Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Eleonora Bazzini"'
Adhesion molecules as potential targets for neuroprotection in a rodent model of Parkinson's disease
Autor:
Marie-Therese Armentero, Giovanna Levandis, Eleonora Bazzini, Silvia Cerri, Cristina Ghezzi, Fabio Blandini
Publikováno v:
Neurobiology of Disease, Vol 43, Iss 3, Pp 663-668 (2011)
Cell adhesion molecules might play an important role in the inflammatory mechanisms associated with neurodegeneration. We have previously observed, in rats, that subcutaneous injection of complete Freund's adjuvant (CFA), a pro-inflammatory agent tha
Externí odkaz:
https://doaj.org/article/07bffa4c12094092856a31541e4e2a0a
Publikováno v:
Neurobiology of Disease, Vol 29, Iss 1, Pp 161-168 (2008)
Altered glutamatergic neurotransmission is central to the expression of Parkinson's disease (PD) symptoms and may underlie l-DOPA-induced dyskinesias. Drugs acting on glutamate metabotropic receptors (mGluR) of group I can modulate subthalamic nucleu
Externí odkaz:
https://doaj.org/article/cceda146692e46059bcc6e3ca0e43f2c
Publikováno v:
Neurobiology of Disease, Vol 24, Iss 3, Pp 492-505 (2006)
Complete Freund's adjuvant (CFA), a pro-inflammatory agent, was inoculated, subcutaneously, to Sprague–Dawley rats prior to the intrastriatal injection of 6-hydroxydopamine (6-OHDA). Animals were sacrificed 7 and 28 days following 6-OHDA injection;
Externí odkaz:
https://doaj.org/article/f2a37aef933c4f15aa92e7d4558d476f
Autor:
Sergio Lecchini, Giuseppe Nappi, Marie Therese Armentero, Emilia Martignoni, Marco Cosentino, Fabio Blandini, Claudio Pacchetti, Eleonora Bazzini, F. Saporiti, Roberta Zangaglia, Franca Marino
Publikováno v:
Clinical Neuropharmacology. 32:133-139
Long-term treatment of Parkinson disease (PD) is frequently associated with l-3,4-dihydroxyphenylalanine (L-DOPA)-induced dyskinesias (LIDs). L-DOPA-induced dyskinesias are likely due to changes in the signal transduction pathways, at the striatal le
Publikováno v:
European Journal of Neuroscience. 25:397-405
Despite the progressive development of innovative animal models for Parkinson's disease, the intracerebral infusion of neurotoxin 6-hydroxydopamine (6-OHDA) remains the most widely used means to induce an experimental lesion of the nigrostriatal path
Publikováno v:
Neurobiology of Disease, Vol 24, Iss 3, Pp 492-505 (2006)
Complete Freund's adjuvant (CFA), a pro-inflammatory agent, was inoculated, subcutaneously, to Sprague-Dawley rats prior to the intrastriatal injection of 6-hydroxydopamine (6-OHDA). Animals were sacrificed 7 and 28 days following 6-OHDA injection; n
Autor:
Roberta Zangaglia, Claudio Pacchetti, Fabio Blandini, E. Sinforiani, Alberta Samuele, Eleonora Bazzini, Emilia Martignoni, G. Nappi
Publikováno v:
Neurology. 66:529-534
Defects of the ubiquitin-proteasome (UP) system, a multicatalytic complex degrading polyubiquitinated proteins, may intervene in the pathogenesis of neurodegenerative disorders characterized by intracellular formation of protein aggregates such as Pa
Autor:
Marie Therese Armentero, Anna Mangiagalli, Plinio Richelmi, Andrea Ferrigno, Eleonora Bazzini, R. Fancellu, Fabio Blandini, Giuseppe Nappi, Mariapia Vairetti, Alberta Samuele
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1741:325-330
Wilson's disease (WD) is an inherited disorder, characterized by selective copper deposition in liver and brain, chronic hepatitis and extra-pyramidal signs. In this study, we investigated changes of biochemical markers of oxidative stress and apopto
Adhesion molecules as potential targets for neuroprotection in a rodent model of Parkinson's disease
Autor:
Marie Therese Armentero, Fabio Blandini, Giovanna Levandis, Cristina Ghezzi, Eleonora Bazzini, Silvia Cerri
Publikováno v:
Neurobiology of Disease, Vol 43, Iss 3, Pp 663-668 (2011)
Cell adhesion molecules might play an important role in the inflammatory mechanisms associated with neurodegeneration. We have previously observed, in rats, that subcutaneous injection of complete Freund's adjuvant (CFA), a pro-inflammatory agent tha
Autor:
Marisa Faniglione, Mario Colucci, R. De Giorgio, Paolo Clavenzani, Eleonora Bazzini, Cristina Tassorelli, Marila Cervio, B. Balestra, Simone Vigneri, Giovanna Levandis, Fabio Blandini, Rosaria Greco, Marcello Tonini, Giuseppe Nappi
Publikováno v:
Neuroscience letters. 467(3)
Patients with Parkinson’s disease develop motor disturbances often accompanied by peripheral autonomic dysfunctions, including gastrointestinal disorders, such as dysphagia, gastric stasis and constipation. While the mechanisms subserving enteric a