Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Eleonora A. M. Festen"'
Autor:
Shixian Hu, Arno R. Bourgonje, Ranko Gacesa, Bernadien H. Jansen, Johannes R. Björk, Amber Bangma, Iwan J. Hidding, Hendrik M. van Dullemen, Marijn C. Visschedijk, Klaas Nico Faber, Gerard Dijkstra, Hermie J. M. Harmsen, Eleonora A. M. Festen, Arnau Vich Vila, Lieke M. Spekhorst, Rinse K. Weersma
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Disrupted host-microbe interactions at the mucosal level are key to the pathophysiology of IBD. This study aimed to comprehensively examine crosstalk between mucosal gene expression and microbiota in patients with IBD. To study tissue-specif
Externí odkaz:
https://doaj.org/article/7d585f4cd17d4027b8c1cce58bfea380
Autor:
J. Casper Swarte, Tim J. Knobbe, Johannes R. Björk, Ranko Gacesa, Lianne M. Nieuwenhuis, Shuyan Zhang, Arnau Vich Vila, Daan Kremer, Rianne M. Douwes, Adrian Post, Evelien E. Quint, Robert A. Pol, Bernadien H. Jansen, TransplantLines investigators, Martin H. de Borst, Vincent E. de Meijer, Hans Blokzijl, Stefan P. Berger, Eleonora A. M. Festen, Alexandra Zhernakova, Jingyuan Fu, Hermie J. M. Harmsen, Stephan J. L. Bakker, Rinse K. Weersma
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Kidney transplant recipients (KTR) have impaired health-related quality of life (HRQoL) and suffer from intestinal dysbiosis. Increasing evidence shows that gut health and HRQoL are tightly related in the general population. Here, we investi
Externí odkaz:
https://doaj.org/article/cdeb8a6b39384ab38c6f1bc5cddf08f1
Autor:
Arno R. Bourgonje, Sietse J. Wichers, Shixian Hu, Hendrik M. van Dullemen, Marijn C. Visschedijk, Klaas Nico Faber, Eleonora A. M. Festen, Gerard Dijkstra, Janneke N. Samsom, Rinse K. Weersma, Lieke M. Spekhorst
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Fatigue is a common and clinically challenging symptom in patients with inflammatory bowel diseases (IBD), occurring in ~ 50% of patients with quiescent disease. In this study, we aimed to investigate whether fatigue in patients with clinica
Externí odkaz:
https://doaj.org/article/1ca027029dca4c7482e2e2e9d0f9249d
Autor:
Werna T. C. Uniken Venema, Aarón D. Ramírez-Sánchez, Emilia Bigaeva, Sebo Withoff, Iris Jonkers, Rebecca E. McIntyre, Mennatallah Ghouraba, Tim Raine, Rinse K. Weersma, Lude Franke, Eleonora A. M. Festen, Monique G. P. van der Wijst
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Single-cell RNA sequencing (scRNA-seq) has revolutionized the study of the cellular landscape of organs. Most single-cell protocols require fresh material, which limits sample size per experiment, and consequently, introduces batch effects.
Externí odkaz:
https://doaj.org/article/ea1f79c0e77a4d50adbee714e2e2a5a2
Autor:
Antonius T. Otten, Arno R. Bourgonje, Petra P. Horinga, Hedwig H. van der Meulen, Eleonora A. M. Festen, Hendrik M. van Dullemen, Rinse K. Weersma, Coretta C. van Leer-Buter, Gerard Dijkstra, Marijn C. Visschedijk
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionPatients with Inflammatory Bowel Disease (IBD) frequently receive immunomodulating treatment, which may render them at increased risk of an attenuated immune response upon vaccination. In this study, we assessed the effects of different t
Externí odkaz:
https://doaj.org/article/56f0e304104d4b58ab94dda216154f64
Autor:
Marta S. Alexdottir, Arno R. Bourgonje, Morten A. Karsdal, Martin Pehrsson, Roberta Loveikyte, Hendrik M. van Dullemen, Marijn C. Visschedijk, Eleonora A. M. Festen, Rinse K. Weersma, Klaas Nico Faber, Gerard Dijkstra, Joachim H. Mortensen
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundCrohn’s disease (CD) is characterized by excessive protease activity and extracellular matrix (ECM) remodeling. To date, 30–50% of patients experience non-response to anti-TNF-α treatment. This study aimed to assess whether serological
Externí odkaz:
https://doaj.org/article/fff2a2308066439c9000ede3fd3ae70f
Autor:
Marta S. Alexdottir, Arno R. Bourgonje, Morten A. Karsdal, Martin Pehrsson, Roberta Loveikyte, Hendrik M. van Dullemen, Marijn C. Visschedijk, Eleonora A. M. Festen, Rinse K. Weersma, Klaas Nico Faber, Gerard Dijkstra, Joachim H. Mortensen
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8137 (2022)
Crohn’s disease (CD) is a relapsing-remitting inflammatory disease of the gastrointestinal (GI) tract characterized by increased extracellular matrix (ECM) remodeling. The introduction of the α4β7-integrin inhibitor vedolizumab (VEDO) has improve
Externí odkaz:
https://doaj.org/article/86aec7cd862f4bb7a5aa85eb0a5b04aa
Autor:
Arno R. Bourgonje, Laura A. Bolte, Lianne L. C. Vranckx, Lieke M. Spekhorst, Ranko Gacesa, Shixian Hu, Hendrik M. van Dullemen, Marijn C. Visschedijk, Eleonora A. M. Festen, Janneke N. Samsom, Gerard Dijkstra, Rinse K. Weersma, Marjo J. E. Campmans-Kuijpers
Publikováno v:
Nutrients, Vol 14, Iss 12, p 2522 (2022)
Diet plays an important role in the development and progression of inflammatory bowel disease (IBD, comprising Crohn’s disease (CD) and ulcerative colitis (UC)). However, little is known about the extent to which different diets reflect inflammatio
Externí odkaz:
https://doaj.org/article/bd6885e67ab74d469afcf02ea988b4a1
Autor:
Arno R. Bourgonje, Reinier C. A. van Linschoten, Rachel L. West, Maarten A. van Dijk, Coretta C. van Leer-Buter, Gursah Kats-Ugurlu, Marieke J. Pierik, Eleonora A. M. Festen, Rinse K. Weersma, Gerard Dijkstra
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 14 (2021)
In the wake of the coronavirus disease 2019 (COVID-19) pandemic, it is unclear how asymptomatic severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-infected patients who present with acute severe ulcerative colitis (UC) can be treated effect
Externí odkaz:
https://doaj.org/article/3df5814880f04332a481288eabae23b4
Autor:
Naomi Karmi, Amber Bangma, Lieke M Spekhorst, Hendrik M van Dullemen, Marijn C Visschedijk, Gerard Dijkstra, Rinse K Weersma, Michiel D Voskuil, Eleonora A M Festen
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0256860 (2021)
BackgroundAnti-tumour necrosis factor alpha (TNFα) therapy is widely used in the management of Crohn's disease (CD) and ulcerative colitis (UC). However, up to a third of patients do not respond to induction therapy and another third of patients los
Externí odkaz:
https://doaj.org/article/7e6c3516725d43519dd43909c7f20bd4