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pro vyhledávání: '"Eleni-Anastasia Triantafyllou"'
Οι επαγόμενοι από την υποξία παράγοντες HIF μεσολαβούν την επιβίωση φυσιολογικών κυττάρων σε χαμηλές συγκεντρώσεις οξυγόνου και καρκινι
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d30c2b751d8995471c8d5709b8720259
https://doi.org/10.12681/eadd/43750
https://doi.org/10.12681/eadd/43750
Publikováno v:
Hypoxia
Hypoxia and its key mediators hypoxia inducible Factors (HIFs) are implicated in the development of liver diseases of diverse etiologies, often in interplay with inflammatory mediators. We investigated the interplay between hypoxia and proinflammator
Autor:
Ilias Mylonis, Efrosyni Paraskeva, George Simos, Eleni Georgatsou, Eleni-Anastasia Triantafyllou
Publikováno v:
Biochimica et biophysica acta. Molecular and cell biology of lipids. 1863(9)
Hypoxia inducible factor-1 (HIF-1) supports survival of normal cells under low oxygen concentration and cancer cells in the hypoxic tumor microenvironment. This involves metabolic reprogramming via upregulation of glycolysis, downregulation of oxidat