Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Eleni V Dimaraki"'
Publikováno v:
Journal of the Endocrine Society. 5:A459-A460
Background: The transition from pediatric to adult type 1 diabetes (TID) care represents a vulnerable period for young adults (YA), and many are eventually lost to follow up. This can result in lost opportunities for patient education, worsened glyce
Autor:
Soo Young Kim, Craig A. Jaffe, Vasantha Padmanabhan, Ronald Taussig, Eleni V. Dimaraki, Ariel L. Barkan, William F. Chandler, Morton B. Brown
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 91:2185-2190
Some indirect evidence suggests hypothalamic control of GH secretion in acromegaly.The objective of the study is to examine whether GH secretion in acromegaly is dependent on endogenous GHRH.We studied eight patients with untreated acromegaly due to
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 90:2117-2121
The diagnosis of acromegaly is suspected based on the typical clinical presentation and is subsequently confirmed biochemically by elevated GH and IGF-I concentrations. We report three female patients with pituitary tumors who presented without any s
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 89:3255-3260
Normal aging in men is accompanied by lower serum testosterone (T), GH, and IGF-I concentrations. The mechanisms of the age-related diminution in the activity of the somatotropic axis (somatopause) are uncertain. Several explanations have been propos
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 88:4776-4780
GH secretory patterns in humans are sexually dimorphic in terms of pulse regularity, amplitude of the diurnal rhythm, and magnitude of basal (trough) secretion. The neuroendocrine mechanisms of gender-specific GH regulation in humans are currently un
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 285:E163-E170
Using a continuous subcutaneous octreotide infusion to create constant supraphysiological somatostatinergic tone, we have previously shown that growth hormone (GH) pulse generation in women is independent of endogenous somatostatin (SRIH) declines. G
Autor:
Craig A. Jaffe, Eleni V. Dimaraki, William F. Chandler, Roberta DeMott-Friberg, Ariel L. Barkan
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 87:3537-3542
The biochemical diagnosis of acromegaly is conventionally based on elevated plasma GH levels that fail to suppress after an oral glucose load. We studied 16 newly diagnosed patients with acromegaly with normal mean plasma GH but elevated age and gend
Autor:
Eleni V. Dimaraki, Wesley P. Fairfield, Laurence Katznelson, Gemma Sesmilo, Pamela U. Freda, K Pulaski, Mary Lee Vance, Douglas Hayden, Stavros Stavrou, Vivien Bonert, Anne Klibanski
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 87:1692-1699
Acromegaly is associated with premature cardiovascular mortality. GH replacement therapy decreases inflammatory markers of cardiovascular risk, but little is known about these markers in patients with acromegaly. The GH receptor antagonist, pegvisoma
Autor:
Craig A. Jaffe, Cyril Y. Bowers, Eleni V. Dimaraki, Peter Marbach, Roberta DeMott-Friberg, Mary Russell-Aulet, Ariel L. Barkan
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 280:E489-E495
To test whether endogenous hypothalamic somatostatin (SRIH) fluctuations are playing a role in the generation of growth hormone (GH) pulses, continuous subcutaneous octreotide infusion (16 μg/h) was used to create constant supraphysiological somatos
Autor:
Eleni V. Dimaraki, Craig A. Jaffe
Publikováno v:
Reviews in endocrinemetabolic disorders. 7(4)
Ghrelin, a 28-amino acid hormone that is acylated post-translation, is the endogenous ligand for the growth hormone (GH) secretagogue (GHS) receptor (GHS-R). The highest concentrations of ghrelin are found in the stomach; however ghrelin peptide is a