Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Eleni Topkas"'
Autor:
Liliana Endo-Munoz, Na Cai, Andrew Cumming, Rebecca Macklin, Lilia Merida de Long, Eleni Topkas, Pamela Mukhopadhyay, Michelle Hill, Nicholas A Saunders
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0133592 (2015)
Pulmonary metastasis is the major untreatable complication of osteosarcoma (OS) resulting in 10-20% long-term survival. The factors and pathways regulating these processes remain unclear, yet their identification is crucial in order to find new thera
Externí odkaz:
https://doaj.org/article/659d63ddc58c40a2a08f5b9ea856210c
Autor:
Nicholas A. Saunders, Liliana Endo-Munoz, Fiona Simpson, Pamela Mukhopadhyay, Marcin Dzienis, Ana Cristina Vargas, Samuel Boros, Eleni Topkas, Orla M. Gannon, Lilia Merida de Long, Mehlika Hazar-Rethinam
Figure S2. Adenovirus infection of murine keratinocytes does not alter normal cell responses.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0df2da1c980d9b4d5cb4741d6492c1b4
https://doi.org/10.1158/1078-0432.22460970
https://doi.org/10.1158/1078-0432.22460970
Autor:
Nicholas A. Saunders, Liliana Endo-Munoz, Fiona Simpson, Pamela Mukhopadhyay, Marcin Dzienis, Ana Cristina Vargas, Samuel Boros, Eleni Topkas, Orla M. Gannon, Lilia Merida de Long, Mehlika Hazar-Rethinam
The file contains figure legends for 6 supplementary figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf6757faaad3a07a791048073bef3af9
https://doi.org/10.1158/1078-0432.22460955.v1
https://doi.org/10.1158/1078-0432.22460955.v1
Autor:
Nicholas A. Saunders, Liliana Endo-Munoz, Fiona Simpson, Pamela Mukhopadhyay, Marcin Dzienis, Ana Cristina Vargas, Samuel Boros, Eleni Topkas, Orla M. Gannon, Lilia Merida de Long, Mehlika Hazar-Rethinam
Purpose: Head and neck squamous cell carcinomas (HNSCC) are frequently drug resistant and have a mortality rate of 45%. We have previously shown that E2F7 may contribute to drug resistance in SCC cells. However, the mechanism and pathways involved re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0212cd25a1412b06361d4a95df861e97
https://doi.org/10.1158/1078-0432.c.6524655
https://doi.org/10.1158/1078-0432.c.6524655
Autor:
Tina Baillie, Julie Burn, Victoria Jones, Anthony J. Gill, Anna Lapuk, Roger H. Kim, Anita Muljono, Yesser Zein, James Harraway, Eric Gagne, Cathy Lim, Melissa K. McConechy, Kambin Nejad, Eric Lee, Fiona Maclean, Ana Cristina Vargas, Michael Walsh, Eleni Topkas
Publikováno v:
Pathology. 52:410-420
We sought to review the prevalence of EGFR T790M and other EGFR mutations associated with either proven or probable tyrosine kinase inhibitor (TKI) resistance in the Australasian lung cancer population and to perform histopathological correlation in
Publikováno v:
Journal of Clinical Pathology. 74:43-47
AimsOsimertinib is a third-generation EGFR (epidermal growth factor receptor) tyrosine kinase inhibitor that is effective in non-small cell lung cancer (NSCLC) harbouring the EGFR T790M mutation. The Idylla EGFR Mutation Test is a rapid cartridge-bas
Publikováno v:
Journal of clinical pathology. 74(1)
Osimertinib is a third-generationEighty NSCLC samples were tested by both Idylla and a next-generation sequencing (NGS) assay; 46 were from patients at disease progression, and 24 of these had known T790M mutations. Droplet digital PCR (ddPCR) was us
Autor:
Douglas H. Thamm, S. Sommerville, Maurine J. Thomson, Tristram C. Bennett, Liliana Endo-Munoz, Rodney C. Straw, Kathleen O'Connell, Amy Lane, Eleni Topkas, Sherry Y. Wu, Nicholas Matigian, Maureen Cooper, Nicholas A. Saunders, Guy Bird, A. E. Peaston, Laura Brockley
Publikováno v:
Veterinary and comparative oncologyREFERENCES. 18(2)
Osteosarcoma is the most common paediatric primary bone malignancy. The major cause of death in osteosarcoma is drug-resistant pulmonary metastasis. Previous studies have shown that thioredoxin reductase 2 is a driver of metastasis in osteosarcoma an
Autor:
Liliana Endo-Munoz, Haolu Wang, Sally Martin, Rebecca Macklin, Na Cai, Natalia Saenz Ponce, A. Cumming, Dorothy Loo, Kerry L. Inder, Rebecca E. Lane, Eleni Topkas, Nicholas A. Saunders
Publikováno v:
Oncotarget
Osteosarcoma (OS) is the most common pediatric bone tumor and is associated with the emergence of pulmonary metastasis. Unfortunately, the mechanistic basis for metastasis remains unclear. Tumor-derived extracellular vesicles (EVs) have been shown to
Autor:
Mehlika Hazar-Rethinam, Na Cai, Eleni Topkas, Melinda Burgess, A. Cumming, Nicholas A. Saunders, Orla M. Gannon, Liliana Endo-Munoz
Publikováno v:
Oncotarget
Osteosarcoma (OS) accounts for 56% of malignant bone cancers in children and adolescents. Patients with localized disease rarely develop metastasis; however, pulmonary metastasis occurs in approximately 50% of patients and leads to a 5-year survival