Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Eleni Maria Varypataki"'
Supplementary Table 1: Loading efficiencies of OVA24 and OVA17 in liposomes Supplementary fig.1: Loading of OVA17 and OVA24 in liposomes as function of adjustable initial peptide concentration Supplementary Table 2:Physicochemical properties of lipos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f444b40bccb69c88f9980adfb4ae273
https://doi.org/10.1158/2326-6066.22537610.v1
https://doi.org/10.1158/2326-6066.22537610.v1
Therapeutic vaccination with synthetic long peptides (SLP) can be clinically effective against HPV-induced premalignant lesions; however, their efficiency in established malignant lesions leaves room for improvement. Here, we report the high therapeu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9a660fefe84fe8e3507161489757a3f
https://doi.org/10.1158/2326-6066.c.6548498.v1
https://doi.org/10.1158/2326-6066.c.6548498.v1
Autor:
Eleni Maria Varypataki, Fabio Hasler, Ying Waeckerle-Men, Sarah Vogel-Kindgen, Anders Høgset, Thomas M. Kündig, Bruno Gander, Cornelia Halin, Pål Johansen
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Cytotoxic T lymphocytes (CTLs) are key players in fighting cancer, and their induction is a major focus in the design of therapeutic vaccines. Yet, therapeutic vaccine efficacy is limited, in part due to the suboptimal vaccine processing by antigen-p
Externí odkaz:
https://doaj.org/article/c0096178e37541498f79e584f063610e
Autor:
Maria Karagianni, Eleni Maria Varypataki, Valeria Nicolini, Christian Münz, Pablo Umana, Christian Klein, Laura Codarri Deak
Publikováno v:
Cancer Research. 82:2070-2070
PD1-IL2v is a novel immunocytokine constituted by a high affinity bivalent blocking PD-1 antibody and a heterodimeric silent Fc-part fused to a monomeric IL-2 variant (IL2v). In contrast to wildtype IL2, IL2v does not bind to CD25 (IL2Ra) and, theref
Autor:
Philipp Schineis, Sarah Vogel-Kindgen, Martine Theisen, Zuzanna K. Kotkowska, Pål Johansen, Saurav Subedi, Mona C. Friess, Isabel Kolm, Ying Waeckerle-Men, Thomas M. Kündig, David Schwyter, Eleni Maria Varypataki, Anders Høgset, Lucy Hausammann, Bruno Gander, Cornelia Halin
Antigen cross-presentation to cytotoxic CD8+ T cells is crucial for the induction of anti-tumor and anti-viral immune responses. Recently, co-encapsulation of photosensitizers and antigens into microspheres and subsequent photochemical internalizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2685436b07fa5daf767fe0f63276e72e
https://www.zora.uzh.ch/id/eprint/209624/
https://www.zora.uzh.ch/id/eprint/209624/
Autor:
Manfred Claassen, Anne Greet Bittermann, Christina Fassnacht, Yun-Tsan Chang, Eleni Maria Varypataki, Philip Knuckles, Martina Ugrinic, Corinne C Widmer, Kilian Eyerich, Emmanuella Guenova, Sarah H. Carl, Jean-Pierre Bourquin, Maya Vonow-Eisenring, Wolfram Hoetzenecker, Steve Pascolo, Yi-Chien Tsai, Alexandre Theocharides, Desislava Ignatova
Publikováno v:
European Journal of Cancer. 156:S5-S6
Background: In cancer, the lack of early diagnostic biomarkers is a challenge, results in delayed diagnosis, and can seriously affect treatment and prognosis. Therefore, defining accurate methods for early identification of rare malignant cells is of
Autor:
Laura, Codarri Deak, Valeria, Nicolini, Masao, Hashimoto, Maria, Karagianni, Petra C, Schwalie, Laura, Lauener, Eleni Maria, Varypataki, Marine, Richard, Esther, Bommer, Johannes, Sam, Stefanie, Joller, Mario, Perro, Floriana, Cremasco, Leo, Kunz, Emilio, Yanguez, Tamara, Hüsser, Ramona, Schlenker, Marisa, Mariani, Vinko, Tosevski, Sylvia, Herter, Marina, Bacac, Inja, Waldhauer, Sara, Colombetti, Xavier, Gueripel, Stephan, Wullschleger, Melanie, Tichet, Douglas, Hanahan, Haydn T, Kissick, Stephane, Leclair, Anne, Freimoser-Grundschober, Stefan, Seeber, Volker, Teichgräber, Rafi, Ahmed, Christian, Klein, Pablo, Umaña
Publikováno v:
Nature. 610(7930)
Expansion and differentiation of antigen-experienced PD-1
Autor:
Desislava Ignatova, Yun-Tsan Chang, Ieva Saulite, Wolfram Hoetzenecker, Malgorzata Bobrowicz, Steve Pascolo, Julia Scarisbrick, Emmanuella Guenova, Florian Anzengruber, Christina Fassnacht, Florentia Dimitriou, Mirjam Nägeli, Reinhard Dummer, Antonio Cozzio, Eleni Maria Varypataki
Publikováno v:
Oncoimmunology, vol. 9, no. 1, pp. 1738797
OncoImmunology, Vol 9, Iss 1 (2020)
Oncoimmunology
OncoImmunology, Vol 9, Iss 1 (2020)
Oncoimmunology
Sézary syndrome (SS) is an aggressive leukemic variant of cutaneous T-cell lymphoma (L-CTCL) that arises from malignant clonally derived skin-homing CD4 + T cells. Based on advancements in our understanding of the mechanisms underlying L-CTCL, boost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::429af0b064585f2384d099c844567f35
https://serval.unil.ch/resource/serval:BIB_E73C64998C98.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_E73C64998C98.P001/REF.pdf
Autor:
Jeroen Heuts, Anton G. T. Terwisscha van Scheltinga, Wim Jiskoot, Stefan Romeijn, Ferry Ossendorp, Eleni Maria Varypataki, Koen van der Maaden, Jan W. Drijfhout
Publikováno v:
Pharmaceutical Research, 35, 207. SPRINGER/PLENUM PUBLISHERS
Pharmaceutical Research, 35(11)
Pharmaceutical Research
Pharmaceutical Research, 35(11)
Pharmaceutical Research
Purpose Personalized peptide-based cancer vaccines will be composed of multiple patient specific synthetic long peptides (SLPs) which may have various physicochemical properties. To formulate such SLPs, a flexible vaccine delivery system is required.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38f3bb2bf9fa5204877c43859aaa88e1
https://hdl.handle.net/1887/66702
https://hdl.handle.net/1887/66702
Autor:
Eleni Maria Varypataki, Wim Jiskoot, Nicolas Collin, Ferry Ossendorp, Ana Luisa Silva, Christophe Barnier-Quer
Publikováno v:
Journal of Controlled Release, 226, 98-106
Nanoparticulate formulations for synthetic long peptide (SLP)-cancer vaccines as alternative to clinically used Montanide ISA 51- and squalene-based emulsions are investigated in this study. SLPs were loaded into TLR ligand-adjuvanted cationic liposo