Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Eleni Manoli"'
The Pseudomonas aeruginosa T6SS Delivers a Periplasmic Toxin that Disrupts Bacterial Cell Morphology
Autor:
Thomas E. Wood, Sophie A. Howard, Andreas Förster, Laura M. Nolan, Eleni Manoli, Nathan P. Bullen, Hamish C.L. Yau, Abderrahman Hachani, Richard D. Hayward, John C. Whitney, Waldemar Vollmer, Paul S. Freemont, Alain Filloux
Publikováno v:
Cell Reports, Vol 29, Iss 1, Pp 187-201.e7 (2019)
Summary: The type VI secretion system (T6SS) is crucial in interbacterial competition and is a virulence determinant of many Gram-negative bacteria. Several T6SS effectors are covalently fused to secreted T6SS structural components such as the VgrG s
Externí odkaz:
https://doaj.org/article/07cd4f7617e14de7be13b4caed130038
Publikováno v:
Statistical Papers.
In many fields of applied research, mostly in sociological, economic, demographic and medical studies, misreporting due to untruthful responding represents a nonsampling error that frequently occurs especially when survey participants are presented w
Autor:
Eleni Manoli
Στόχος της διατριβής είναι η διατύπωση και η επαλήθευση μεθοδολογικού και υπολογιστικού πλαισίου για: (α) τη συστηματική ανάλυση μέτρων
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6890303219f2a9d6092230a56c24b2f2
https://doi.org/10.12681/eadd/40350
https://doi.org/10.12681/eadd/40350
Autor:
Maria A Sainz-Polo, Julian Parkhill, Amy K. Cain, Laura M. Nolan, Alain Filloux, Despoina A. I. Mavridou, Gordon Dougan, David Albesa-Jové, R. Christopher D. Furniss, Thomas Clamens, Eleni Manoli
Publikováno v:
Nature microbiology
The Type VI secretion system (T6SS) is a bacterial nanomachine that delivers toxic effectors to kill competitors or subvert some of their key functions. Here, we use transposon directed insertion-site sequencing to identify T6SS toxins associated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf7628faddbd11f2df6475c46e2a11e4
http://hdl.handle.net/10261/311079
http://hdl.handle.net/10261/311079
Autor:
Maria A Sainz-Polo, David Albesa-Jové, Alain Filloux, Laura M. Nolan, Eleni Manoli, Amy K. Cain, Despoina A. I. Mavridou, Julian Parkhill, Gordon Dougan
SUMMARYThe Type VI secretion system (T6SS) is a bacterial weapon which delivers toxic effectors to kill competitors or subvert some of their key functions. Here we usetransposondirected insertion-sitesequencing (TraDIS) to identify T6SS toxins associ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6793a2bf30a329979afd002a1832ed4
The Pseudomonas aeruginosa T6SS Delivers a Periplasmic Toxin that Disrupts Bacterial Cell Morphology
Autor:
Hamish C. L. Yau, Thomas E. Wood, Nathan P Bullen, Abderrahman Hachani, John C. Whitney, Laura M. Nolan, Andreas Förster, Sophie A. Howard, Eleni Manoli, Richard D. Hayward, Alain Filloux, Waldemar Vollmer, Paul S. Freemont
Publikováno v:
Cell Reports, Vol 29, Iss 1, Pp 187-201.e7 (2019)
201.e7
Cell Reports
201.e7
Cell Reports
Summary The type VI secretion system (T6SS) is crucial in interbacterial competition and is a virulence determinant of many Gram-negative bacteria. Several T6SS effectors are covalently fused to secreted T6SS structural components such as the VgrG sp
Autor:
Lasse Stach, Sara Planamente, Sjors H.W. Scheres, James M. MacDonald, Shaoda He, Eleni Manoli, Paul S. Freemont, Osman Salih, Alain Filloux
Publikováno v:
336.e3
Structure(London, England:1993)
Structure(London, England:1993)
Summary Pseudomonas aeruginosa has three type VI secretion systems (T6SSs), H1-, H2-, and H3-T6SS, each belonging to a distinct group. The two T6SS components, TssB/VipA and TssC/VipB, assemble to form tubules that conserve structural/functional homo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7549277a514ad5f8a4bd874ce1cd106
http://hdl.handle.net/10044/1/56130
http://hdl.handle.net/10044/1/56130
Autor:
Andreas Förster, Sara Planamente, Paul S. Freemont, Nadine S. Lossi, Eleni Manoli, Alain Filloux
Publikováno v:
The Journal of Biological Chemistry
Background: The bacterial type VI secretion apparatus is a phage tail-like structure that secretes toxins/effectors. Results: Four components of the type VI secretion system have coevolved and interact. Conclusion: Distinct classes of type VI secreti
Autor:
Kailyn Hui, Sarah J. Coulthurst, Paul S. Freemont, Rana Dajani, Nadine S. Lossi, Alain Filloux, Peter Simpson, Cerith Jones, Eleni Manoli
Publikováno v:
Molecular Microbiology. 86:437-456
In Pseudomonas aeruginosa three type VI secretion systems (T6SSs) coexist, called H1- to H3-T6SSs. Several T6SS components are proposed to be part of a macromolecular complex resembling the bacteriophage tail. The T6SS protein HsiE1 (TagJ) is unique
Autor:
Derrick J. P. Squire, Denisse L. Leyton, Pooja Sridhar, Michael Overduin, Roy R. Chaudhuri, Timothy J. Knowles, Douglas F. Browning, Ashley H. Spencer, Ian R. Henderson, Sandya Rajesh, Mark Jeeves, Danielle Emery, Mark R. Viant, Ulf Sommer, Riyaz Maderbocus, Adam F. Cunningham, Eleni Manoli
Publikováno v:
EMBO reports. 12:123-128
Insertion of folded proteins into the outer membrane of Gram-negative bacteria is mediated by the essential β-barrel assembly machine (Bam). Here, we report the native structure and mechanism of a core component of this complex, BamE, and show that