FtsZ treadmilling is essential for Z-ring condensation and septal constriction initiation in Bacillus subtilis cell division

Autor: Kevin D. Whitley, Calum Jukes, Nicholas Tregidgo, Eleni Karinou, Pedro Almada, Yann Cesbron, Ricardo Henriques, Cees Dekker, Séamus Holden

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)

Bacterial cell division by cell wall synthesis proteins is guided by treadmilling filaments of the cytoskeleton protein FtsZ. Here authors use nanofabrication, advanced microscopy, and microfluidics to resolve the function of FtsZ treadmilling in the

Externí odkaz: https://doaj.org/article/f128d22694da419c86e73cfe7331df52

Democratising deep learning for microscopy with ZeroCostDL4Mic

Autor: Pieta K. Mattila, Lucas von Chamier, Yoav Shechtman, Elias Nehme, Guillaume Jacquemet, Johanna Jukkala, Alexander Krull, Daniel Krentzel, Loic Royer, Tim-Oliver Buchholz, Mike Heilemann, Christophe Leterrier, Martina Lerche, Romain F. Laine, Ricardo Henriques, Florian Jug, Sara Hernández-Pérez, Martin L. Jones, Eleni Karinou, Ahmet Can Solak, Christoph Spahn, Seamus Holden

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12, ⟨10.1038/s41467-021-22518-0⟩
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications, 2021, 12, ⟨10.1038/s41467-021-22518-0⟩

Deep Learning (DL) methods are powerful analytical tools for microscopy and can outperform conventional image processing pipelines. Despite the enthusiasm and innovations fuelled by DL technology, the need to access powerful and compatible resources

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::020f134a7f24e39c4432fd2895e9d76b
https://hal-amu.archives-ouvertes.fr/hal-03233449/document

FtsZ treadmilling is essential for Z-ring condensation and septal constriction initiation in Bacillus subtilis cell division

Autor: Eleni Karinou, Seamus Holden, Calum Jukes, Ricardo Henriques, Pedro Almada, Cees Dekker, Nicholas Tregidgo, Kevin D. Whitley

Despite the central role of division in bacterial physiology, how division proteins work together as a nanoscale machine to divide the cell remains poorly understood. Cell division by cell wall synthesis proteins is guided by the cytoskeleton protein

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::560ca2e502d7c3af96efe4a8a46a76d7
https://doi.org/10.1101/2020.07.01.182006

Inactivation of the Monofunctional Peptidoglycan Glycosyltransferase SgtB Allows Staphylococcus aureus To Survive in the Absence of Lipoteichoic Acid

Autor: Eleni Karinou, Christopher F. Schuster, Manuel Pazos, Waldemar Vollmer, Angelika Gründling

Publikováno v: Journal of Bacteriology

The bacterial cell wall acts as a primary defense against environmental insults such as changes in osmolarity. It is also a vulnerable structure, as defects in its synthesis can lead to growth arrest or cell death. The important human pathogen Staphy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::778dbccbb9422199d32bd50558321bd9
http://europepmc.org/articles/PMC6287468

TheEscherichia coliSLC26 homologue YchM (DauA) is a C4-dicarboxylic acid transporter

Autor: Eleni Karinou, Mélanie Morel, Emma L R Compton, Arnaud Javelle

Publikováno v: Molecular Microbiology. 87:623-640

The SLC26/SulP (solute carrier/sulphate transporter) proteins are a ubiquitous superfamily of secondary anion transporters. Prior studies have focused almost exclusively on eukaryotic members and bacterial members are frequently classified as sulphat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0c541c7cc7f91bb6f63e01d3d9dd3526
https://doi.org/10.1111/mmi.12120