Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Eleni Gourni"'
Autor:
Tilman Läppchen, Adrianna Bilinska, Eirinaios Pilatis, Elena Menéndez, Surachet Imlimthan, Euy Sung Moon, Ali Afshar-Oromieh, Frank Rösch, Axel Rominger, Eleni Gourni
Publikováno v:
Molecules, Vol 29, Iss 13, p 3093 (2024)
Background: FAP radiopharmaceuticals show promise for cancer diagnosis; however, their limited tumor residency hinders treatment. This study compared two FAPi derivatives, DOTA.SA.FAPi and DOTAGA.(SA.FAPi)2, labeled with gallium-68 and lutetium-177,
Externí odkaz:
https://doaj.org/article/285d4217cb994469b1b11d23d67b90fa
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Breast Cancer (BC) is the most common cancer worldwide and, despite the advancements made toward early diagnosis and novel treatments, there is an urgent need to reduce its mortality. The Gastrin-Releasing Peptide Receptor (GRPR) is a promising targe
Externí odkaz:
https://doaj.org/article/d800166837b94aada0fe363fec5401d8
Autor:
Michael Hofstetter, Euy Sung Moon, Fabio D’Angelo, Lucien Geissbühler, Ian Alberts, Ali Afshar-Oromieh, Frank Rösch, Axel Rominger, Eleni Gourni
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 5, Iss 1, Pp 1-19 (2020)
Abstract Background Gastrin Releasing Peptide receptor (GRPr)-based radioligands have shown great promise for diagnostic imaging of GRPr-positive cancers, such as prostate and breast. The present study aims at developing and evaluating a versatile GR
Externí odkaz:
https://doaj.org/article/4a0fe7b14d8f475ab34e7db297ebd9f2
Publikováno v:
ACS Omega, Vol 4, Iss 6, Pp 9925-9931 (2019)
Externí odkaz:
https://doaj.org/article/2dfe9e5301554cb6a594292f0e036a19
Autor:
Surachet Imlimthan, Euy Sung Moon, Hendrik Rathke, Ali Afshar-Oromieh, Frank Rösch, Axel Rominger, Eleni Gourni
Publikováno v:
Pharmaceuticals, Vol 14, Iss 10, p 1023 (2021)
Over the past decade, the tumor microenvironment (TME) has become a new paradigm of cancer diagnosis and therapy due to its unique biological features, mainly the interconnection between cancer and stromal cells. Within the TME, cancer-associated fib
Externí odkaz:
https://doaj.org/article/c92b212da1a04611a9f34e3bc1ee26ea
Autor:
Eleni Gourni PhD, Luigi Del Pozzo BSc, Mark Bartholomä PhD, Yvonne Kiefer BSc, Philipp T. Meyer MD, PhD, Helmut R. Maecke PhD, Jason P. Holland D.Phil
Publikováno v:
Molecular Imaging, Vol 16 (2017)
Radiotracers incorporating the urea-based Glu-NH-C(O)-NH-Lys group have gained prominence due to their role in targeting prostate-specific membrane antigen (PSMA)—a clinical biomarker of prostate cancer. Here, the synthesis, radiolabeling, and in v
Externí odkaz:
https://doaj.org/article/80fc5fd6557c4066a3ee4da24b33cef8
Autor:
Eleni Gourni, Coline Canovas, Victor Goncalves, Franck Denat, Philipp T Meyer, Helmut R Maecke
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145755 (2015)
PURPOSE:The present study aims at developing and evaluating an urea-based prostate specific membrane antigen (PSMA) inhibitor suitable for labeling with 111In for SPECT and intraoperative applications as well as 68Ga and 64Cu for PET imaging. METHODS
Externí odkaz:
https://doaj.org/article/33c99b2cb1fd46f39c28eaa4110a8fb1
Autor:
Eleni Gourni, Gjermund Henriksen
Publikováno v:
Molecules, Vol 22, Iss 4, p 523 (2017)
Prostate cancer is one of the most common malignancies for which great progress has been made in identifying appropriate molecular targets that would enable efficient in vivo targeting for imaging and therapy. The type II integral membrane protein, p
Externí odkaz:
https://doaj.org/article/17f3851829c6488b9a713b356b67b4d3
Autor:
Surachet Imlimthan, Elena Menéndez, Alondra Escudero-Castellanos, Euy Sung Moon, Tilman Läppchen, Hendrik Rathke, Ali Afshar-Oromieh, Frank Roesch, Axel Rominger, Eleni Gourni
Publikováno v:
Nuclear Medicine and Biology. :S56-S57
Autor:
Alondra Escudero-Castellanos, Surachet Imlimthan, Elena Menéndez, Euy Sung Moon, Tilman Läppchen, Hendrik Rathke, Ali Afshar-Oromieh, Frank Roesch, Axel Rominger, Eleni Gourni
Publikováno v:
Nuclear Medicine and Biology. :S186-S187