Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Eleni Constantopoulos"'
Impact of APOE on amyloid and tau accumulation in argyrophilic grain disease and Alzheimer’s disease
Autor:
Ana-Caroline Raulin, Sydney V. Doss, Michael G. Heckman, Emily C. Craver, Zonghua Li, Tadafumi C. Ikezu, Hiroaki Sekiya, Chia-Chen Liu, Yuka A. Martens, Cassandra L. Rosenberg, Lindsey A. Kuchenbecker, Michael DeTure, R. Ross Reichard, Aivi T. Nguyen, Eleni Constantopoulos, Rachel A. Larsen, Emmaline K. Kounaves, Melissa E. Murray, Dennis W. Dickson, Ronald C. Petersen, Guojun Bu, Takahisa Kanekiyo
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-16 (2024)
Abstract Alzheimer’s disease (AD), characterized by the deposition of amyloid-β (Aβ) in senile plaques and neurofibrillary tangles of phosphorylated tau (pTau), is increasingly recognized as a complex disease with multiple pathologies. AD sometim
Externí odkaz:
https://doaj.org/article/8f5535e35e724bf6989bb41e302e114e
Autor:
Preston R. Harris, Douglas A. Keen, Eleni Constantopoulos, Savanna N. Weninger, Eric Hines, Matthew P. Koppinger, Zain I. Khalpey, John P. Konhilas
Publikováno v:
Journal of the International Society of Sports Nutrition, Vol 16, Iss 1 (2019)
Background Exercise and heat trigger dehydration and an increase in extracellular fluid osmolality, leading to deficits in exercise performance and thermoregulation. Evidence from previous studies supports the potential for deep-ocean mineral water t
Externí odkaz:
https://doaj.org/article/88bcb6c9f92a4c20b7c1430f88f7a043
Autor:
Michelle M. Mielke, Eleni Constantopoulos, Val J. Lowe, Alejandro A. Rabinstein, David T.W. Jones, Dennis W. Dickson, Stuart J. McCarter, Scott A. Przybelski, Ronald C. Petersen, Hugo Botha, Clifford R. Jack, Jonathan Graff-Radford, Timothy G. Lesnick, Prashanthi Vemuri, Melissa E. Murray, R. Ross Reichard, Bradley F. Boeve, Kejal Kantarci, Vijay K. Ramanan, David S. Knopman
Publikováno v:
Neurology
Background and ObjectivesTo determine the contribution of cerebral amyloid angiopathy (CAA) to Pittsburgh compound B (PiB)–PET tracer retention.MethodsParticipants from the Mayo Clinic Study of Aging and Mayo Clinic Alzheimer's Disease Research Cen
Autor:
David T.W. Jones, Scott A. Przybelski, Vijay K. Ramanan, Melissa E. Murray, Hugo Botha, Michelle M. Mielke, Alejandro A. Rabinstein, Bradley F. Boeve, Ronald C. Petersen, Timothy G. Lesnick, Prashanthi Vemuri, Eleni Constantopoulos, Kejal Kantarci, Dennis W. Dickson, R. Ross Reichard, Clifford R. Jack, Jonathan Graff-Radford, David S. Knopman
Publikováno v:
J Alzheimers Dis
OBJECTIVE: To determine whether cerebral microbleeds (CMBs) on antemortem hemosiderin-sensitive MRI sequences correlate with cerebral amyloid angiopathy (CAA). METHODS: We reviewed 54 consecutive patients regardless of diagnosis with antemortem T2*GR
Autor:
Jessica N Sanchez, Danielle K. Cannon, Hao Chen, Yulia Lipovka, Dennis P Pollow, Eleni Constantopoulos, Jessica A. Regan, John P. Konhilas, Rinku Skaria, Laurel A. McKee, Marissa A. Lopez-Pier, Heddwen L. Brooks
Publikováno v:
Am J Physiol Heart Circ Physiol
There is a sharp rise in cardiovascular disease (CVD) risk and progression with the onset of menopause. The 4-vinylcyclohexene diepoxide (VCD) model of menopause recapitulates the natural, physiological transition through perimenopause to menopause.
Autor:
Michael A. Paolini, Parichita Choudhury, Keith A. Josephs, Joseph R. Duffy, Julie A. Fields, R. Ross Reichard, Bradley F. Boeve, David T.W. Jones, Mary M. Machulda, Melissa E. Murray, Dennis W. Dickson, Ronald C. Petersen, David S. Knopman, Jonathan Graff-Radford, Neill R. Graff-Radford, Eleni Constantopoulos, Eugene L. Scharf, Joseph E. Parisi, Eva Alden
Publikováno v:
Journal of Neurology. 267:2697-2704
Pick’s disease (PiD) is a unique subtype of frontotemporal lobar degeneration characterized pathologically by aggregates of 3-Repeat tau. Few studies have examined the clinical variability and disease progression in PiD. We describe the clinical fe
Autor:
Diana P Londoño, Kogulavadanan Arumaithurai, Eleni Constantopoulos, Michael R Basso, R Ross Reichard, Eoin P Flanagan, B Mark Keegan
Publikováno v:
Brain communications. 4(4)
Among people with multiple sclerosis, cognitive impairment occurs commonly and is a potent predictor of disability. Some multiple sclerosis patients present with severe cognitive impairment, and distinguishing multiple sclerosis-related cognitive imp
Autor:
John P. Konhilas, Eric R. Hines, Douglas A. Keen, Eleni Constantopoulos, Savanna N. Weninger, Zain Khalpey, Preston R. Harris, Matthew P. Koppinger
Publikováno v:
Journal of the International Society of Sports Nutrition, Vol 16, Iss 1, Pp 1-12 (2019)
Journal of the International Society of Sports Nutrition
Journal of the International Society of Sports Nutrition
Background Exercise and heat trigger dehydration and an increase in extracellular fluid osmolality, leading to deficits in exercise performance and thermoregulation. Evidence from previous studies supports the potential for deep-ocean mineral water t
Autor:
Yong Guo, Claudia F. Lucchinetti, Kianoush Kashani, Eleni Constantopoulos, Nicholas A. Boire, R. Ross Reichard
Publikováno v:
Acta Neuropathologica
We report the neuropathological findings of a patient who died from complications of COVID-19. The decedent was initially hospitalized for surgical management of underlying coronary artery disease. He developed post-operative complications and was ev
Autor:
Farmin Samareh-Jahani, Carol A. Barnes, Todd W. Vanderah, John P. Konhilas, Eleni Constantopoulos, Ajay R. Uprety, Meredith Hay
Publikováno v:
Behavioral Neuroscience. 131:99-114
Patients with congestive heart failure (CHF) have increased hospital readmission rates and mortality if they are concomitantly diagnosed with cognitive decline and memory loss. Accordingly, we developed a preclinical model of CHF-induced cognitive im