Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Eleni A. Rekka"'
Publikováno v:
Molecules, Vol 29, Iss 16, p 3763 (2024)
Degenerative conditions, such as neurodegenerative disorders (Alzheimer’s disease (AD), Parkinson’s disease (PD)) and cardiovascular diseases, are complex, multifactorial disorders whose pathophysiology has not been fully elucidated yet. As a res
Externí odkaz:
https://doaj.org/article/69461d276c37434b807e7818c02148c8
Publikováno v:
Nutrients, Vol 16, Iss 16, p 2740 (2024)
Vitamins are micronutrients necessary for the normal function of the body. Although each vitamin has different physicochemical properties and a specific role in maintaining life, they may also possess a common characteristic, i.e., antioxidant activi
Externí odkaz:
https://doaj.org/article/8944f63ac0a64985910869d6ce6b0911
Publikováno v:
Molecules, Vol 29, Iss 5, p 1016 (2024)
Amides containing methyl esters of γ-aminobutyric acid (GABA), L-proline and L-tyrosine, and esters containing 3-(pyridin-3-yl)propan-1-ol were synthesized by conjugation with 3,5-di-tert-butyl-4-hydroxybenzoic, an NSAID (tolfenamic acid), or 3-phen
Externí odkaz:
https://doaj.org/article/b91f5d5c3e0b43bb8192bd9c5a0a9da8
Publikováno v:
Molecules, Vol 28, Iss 18, p 6732 (2023)
Oxidative stress and hyperlipidemia are important factors for the initiation and progression of various cell degenerative pathological conditions, including cardiovascular and neurological diseases. A series of cinnamic acid-derived acids, such as fe
Externí odkaz:
https://doaj.org/article/c668038697b94e5bb1e8becfa153dc14
Publikováno v:
Antioxidants, Vol 12, Iss 7, p 1436 (2023)
A series of thiomorpholine and cinnamyl alcohol derivatives, conjugated with cinnamic acid-containing moieties, such as ferulic acid, sinapic acid and 3,4-dimethoxycinnamic acid, were synthesized and tested for their antioxidant, anti-inflammatory an
Externí odkaz:
https://doaj.org/article/11512e5ee98940ed901f529b66b83509
Publikováno v:
Molecules, Vol 27, Iss 23, p 8402 (2022)
Multiple sclerosis (MS) is a complex neurodegenerative disease. Although its pathogenesis is rather vague in some aspects, it is well known to be an inflammatory process characterized by inflammatory cytokine release and oxidative burden, resulting i
Externí odkaz:
https://doaj.org/article/7f25047d0c5a41ac9b0c2690ace8ef9f
Publikováno v:
Molecules, Vol 27, Iss 20, p 6984 (2022)
Alzheimer’s Disease (AD) is a common neurodegenerative disorder characterized by memory loss and cognitive impairment. Its pathology has not been fully clarified and therefore highly effective treatments have not been obtained yet. Almost all the c
Externí odkaz:
https://doaj.org/article/87f2c9c6c3ed44c6b43789dab105ab2c
Autor:
Paraskevi Tziona, Panagiotis Theodosis-Nobelos, Georgios Papagiouvannis, Anthi Petrou, Chryssoula Drouza, Eleni A. Rekka
Publikováno v:
Molecules, Vol 27, Iss 7, p 2104 (2022)
The synthesis of derivatives of three nonspecific COX-1 and COX-2 inhibitors, ibuprofen, ketoprofen, naproxen is presented. These acids were connected via an amide bond with an amino acid (L-proline, L-tyrosine, and beta-alanine) used as a linker. Th
Externí odkaz:
https://doaj.org/article/7b16a4ae00f4426c935699e8814bc112
Autor:
Panagiotis Theodosis-Nobelos, Georgios Papagiouvannis, Paraskevi Tziona, Panos N. Kourounakis, Eleni A. Rekka
Publikováno v:
Molecules, Vol 26, Iss 13, p 4060 (2021)
A series of L-serine amides of antioxidant acids, such as Trolox, (E)-3-(3,5-di-tert-butyl-4-hydroxyphenyl)acrylic acid (phenolic derivative of cinnamic acid) and 3,5-di-tert-butyl-4-hydroxybenzoic acid (structurally similar to butylated hydroxytolue
Externí odkaz:
https://doaj.org/article/65e2bdcb4adf430d90e113bb890447e9
Publikováno v:
Molecules, Vol 24, Iss 18, p 3277 (2019)
Novel derivatives of some non steroidal anti-inflammatory drugs, as well as of the antioxidants α-lipoic acid, trolox and (E)-3-(3,5-di-tert-butyl-4-hydroxyphenyl)acrylic acid with lorazepam were synthesised by a straightforward method at satisfacto
Externí odkaz:
https://doaj.org/article/ef0c28fe00ba4de9896cc454c92598e8