Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Eleni, Pontiki"'
Autor:
Eleni Kavetsou, Ioanna Pitterou, Nikos G. Dimitrioglou, Stefanos Kikionis, Eftichia Kritsi, Panagiotis Zoumpoulakis, Eleni Pontiki, Dimitra Hadjipavlou-Litina, Dimitris T. Hatziavramidis, Anastasia Detsi
Publikováno v:
Micro, Vol 3, Iss 4, Pp 892-911 (2023)
The present study focuses on the synthesis of the natural product 4-methyl-umbelliferone (4-MU, hymecromone), the preparation, characterization, and biological activity evaluation of 4-MU inclusion complexes with β-cyclodextrin (β-CD), as well as t
Externí odkaz:
https://doaj.org/article/24e01ac5a7c44881b2c7c4cc1b831181
Publikováno v:
Antioxidants, Vol 13, Iss 8, p 898 (2024)
Cancer and oxidative stress are interrelated, with reactive oxygen species (ROS) playing crucial roles in physiological processes and oncogenesis. Excessive ROS levels can induce DNA damage, leading to cancer, and disrupt antioxidant defenses, contri
Externí odkaz:
https://doaj.org/article/e1ead2a3ebec418cb55c1ffe1829523c
Autor:
Evangelia-Eirini N. Vlachou, Eleni Pontiki, Dimitra J. Hadjipavlou-Litina, Konstantinos E. Litinas
Publikováno v:
Organics, Vol 4, Iss 3, Pp 364-385 (2023)
New methyl-substituted, and diphenyl-substituted fused dipyranoquinolinones are prepared in excellent yields via the triple bond activation and 6-endo-dig cyclization of propargyloxycoumarin derivatives by gold nanoparticles supported on TiO2 in chlo
Externí odkaz:
https://doaj.org/article/b0dc2810dc3f4625bf31095a2cc60f85
Autor:
Michail Saragatsis, Eleni Pontiki
Publikováno v:
Molecules, Vol 29, Iss 6, p 1189 (2024)
The pyrimidine ring is present in various biomolecules such as DNA and RNA bases, aminoacids, vitamins, etc. Additionally, many clinically used drugs including methotrexate and risperidone contain the pyrimidine heterocyclic scaffold as well. Pyrimid
Externí odkaz:
https://doaj.org/article/099f2326ffe846c8ba568a5b10d379bf
Publikováno v:
Molecules, Vol 28, Iss 24, p 7958 (2023)
Molecular hybridization has emerged as a promising approach in the treatment of diseases exhibiting multifactorial etiology. With regard to this, dual cyclooxygenase-2/lipoxygenase (COX-2/LOX) inhibitors could be considered a safe alternative to trad
Externí odkaz:
https://doaj.org/article/c5dbdc8e059548ab8df660876ab10a8f
Autor:
Ioanna Kostopoulou, Andromachi Tzani, Konstantina Chronaki, Kyriakos C. Prousis, Eleni Pontiki, Dimitra Hadjiplavlou-Litina, Anastasia Detsi
Publikováno v:
Molecules, Vol 29, Iss 1, p 190 (2023)
In this work, the privileged scaffold of 4-hydroxy-2quinolinone is investigated through the synthesis of carboxamides and hybrid derivatives, as well as through their bioactivity evaluation, focusing on the ability of the molecules to inhibit the soy
Externí odkaz:
https://doaj.org/article/cd6a7b2823ec4b4195c1feb79a6cc8fa
Autor:
Aliki Drakontaeidi, Eleni Pontiki
Publikováno v:
Pharmaceuticals, Vol 16, Iss 12, p 1639 (2023)
Research into histone deacetylases (HDACs) has experienced a remarkable surge in recent years. These enzymes are key regulators of several fundamental biological processes, often associated with severe and potentially fatal diseases. Inhibition of th
Externí odkaz:
https://doaj.org/article/8a66533bb98e48809453a6a25dc64224
Autor:
Evangelia-Eirini N. Vlachou, Ioannis Fotopoulos, Catherine Gabriel, Eleni Pontiki, Dimitra J. Hadjipavlou-Litina, Konstantinos E. Litinas
Publikováno v:
European Journal of Medicinal Chemistry Reports, Vol 5, Iss , Pp 100063- (2022)
Bis-fused pyridopyranocoumarins are prepared in excellent yields through the triple bond activation of propargylaminopropargyloxycoumarins or propargylamino (Kontogiorgis et al., 2012; Zhang et al., 2014) [7,8]-fused pyranocoumarins by gold nanoparti
Externí odkaz:
https://doaj.org/article/38e2223aafb541f49bdfbda7811f60a9
Autor:
Malama Myriagkou, Evangelia Papakonstantinou, Georgia-Eirini Deligiannidou, Alexandros Patsilinakos, Christos Kontogiorgis, Eleni Pontiki
Publikováno v:
Molecules, Vol 28, Iss 9, p 3913 (2023)
The heterocyclic ring system of pyrido [2,3-d]pyrimidines is a privileged scaffold in medicinal chemistry, possessing several biological activities. The synthesis of the pyrimidine derivatives was performed via the condensation of a suitable α,β-un
Externí odkaz:
https://doaj.org/article/98efeab15707416e9653a92dfe72cffa
Publikováno v:
Molecules, Vol 28, Iss 3, p 1084 (2023)
Alzheimer’s disease (AD), a neurodegenerative brain disorder that affects millions of people worldwide, is characterized by memory loss and cognitive decline. Low levels of acetylcholine and abnormal levels of beta-amyloid, T protein aggregation, i
Externí odkaz:
https://doaj.org/article/d22b5c2aa94a43eabd913aaa542ab3dd