Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Elena Zenaro"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
CD8+ lymphocytes are adaptive immunity cells with the particular function to directly kill the target cell following antigen recognition in the context of MHC class I. In addition, CD8+ T cells may release pro-inflammatory cytokines, such as tumor ne
Externí odkaz:
https://doaj.org/article/559e1076475340f1a4fa1eb1fa95bdea
Autor:
Lara Toffali, Beatrice D’Ulivo, Cinzia Giagulli, Alessio Montresor, Elena Zenaro, Massimo Delledonne, Marzia Rossato, Barbara Iadarola, Andrea Sbarbati, Paolo Bernardi, Gabriele Angelini, Barbara Rossi, Nicola Lopez, Wolfgang A. Linke, Andreas Unger, Dario Di Silvestre, Louise Benazzi, Antonella De Palma, Sara Motta, Gabriela Constantin, Pierluigi Mauri, Carlo Laudanna
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112516- (2023)
Summary: Response to multiple microenvironmental cues and resilience to mechanical stress are essential features of trafficking leukocytes. Here, we describe unexpected role of titin (TTN), the largest protein encoded by the human genome, in the regu
Externí odkaz:
https://doaj.org/article/170109d87daa42509161d0df15919a04
Autor:
Barbara Rossi, Silvia Dusi, Gabriele Angelini, Alessandro Bani, Nicola Lopez, Vittorina Della Bianca, Enrica Caterina Pietronigro, Elena Zenaro, Carlotta Zocco, Gabriela Constantin
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Th1 and Th17 cell migration into the central nervous system (CNS) is a fundamental process in the pathogenesis of experimental autoimmune encephalomyelitis (EAE), the animal model of multiple sclerosis (MS). Particularly, leptomeningeal vessels of th
Externí odkaz:
https://doaj.org/article/1c5a350d113b4905a40e9c526873466b
Autor:
Praveen Bathini, Isabel Dupanloup, Elena Zenaro, Eleonora Terrabuio, Amrei Fischer, Edona Ballabani, Marie-Agnes Doucey, Lavinia Alberi
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 28, Iss , Pp 100568- (2023)
Background: Studies in rodents and humans have indicated that inflammation outside CNS (systemic inflammation) affects brain homeostasis contributing to neurodevelopmental disorders. Itis becoming increasingly evident that such early insults may also
Externí odkaz:
https://doaj.org/article/6024bdd53787463198cbcab050f653ff
Autor:
Francesca Pettinella, Chiara Lattanzi, Marta Donini, Elena Caveggion, Olivia Marini, Giulia Iannoto, Sara Costa, Elena Zenaro, Tiago Moderno Fortunato, Sara Gasperini, Matteo Giani, Lorenzo Belluomini, Marco Sposito, Jessica Insolda, Ilaria Mariangela Scaglione, Michele Milella, Annalisa Adamo, Ornella Poffe, Vincenzo Bronte, Stefano Dusi, Marco A. Cassatella, Stefano Ugel, Sara Pilotto, Patrizia Scapini
Publikováno v:
Cancers, Vol 15, Iss 21, p 5285 (2023)
The advent of immune checkpoint inhibitors (ICIs), for instance, programmed cell death 1 (PD-1)/PD-1 ligand 1 (PD-L1) blockers, has greatly improved the outcome of patients affected by non-small cell lung cancer (NSCLC). However, most NSCLC patients
Externí odkaz:
https://doaj.org/article/61c25e53ccd1443d99932ff4d508b0f6
Autor:
Sara Costa, Dalila Bevilacqua, Elena Caveggion, Sara Gasperini, Elena Zenaro, Francesca Pettinella, Marta Donini, Stefano Dusi, Gabriela Constantin, Silvia Lonardi, William Vermi, Francesco De Sanctis, Stefano Ugel, Tiziana Cestari, Clare L. Abram, Clifford A. Lowell, Pamela Rodegher, Franco Tagliaro, Giampiero Girolomoni, Marco A. Cassatella, Patrizia Scapini
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundPsoriasis is a chronic skin disease associated with deregulated interplays between immune cells and keratinocytes. Neutrophil accumulation in the skin is a histological feature that characterizes psoriasis. However, the role of neutrophils
Externí odkaz:
https://doaj.org/article/b8b37b1a6ace4838bb7bd76f755ac86f
Autor:
Bruno Santos-Lima, Enrica Caterina Pietronigro, Eleonora Terrabuio, Elena Zenaro, Gabriela Constantin
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Leukocyte migration into the central nervous system (CNS) represents a central process in the development of neurological diseases with a detrimental inflammatory component. Infiltrating neutrophils have been detected inside the brain of patients wit
Externí odkaz:
https://doaj.org/article/063ac0d47a984ba39ff6e86a88fe305f
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/698420c6315d486db70e1d8ef04ac773
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Neurodegenerative diseases are closely related to inflammatory and autoimmune events, suggesting that the dysregulation of the immune system is a key pathological factor. Both multiple sclerosis (MS) and Alzheimer's disease (AD) are characterized by
Externí odkaz:
https://doaj.org/article/1d1008bbf1a244c797cb80c8f70e7517
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Neurodegenerative diseases are progressive degenerative conditions characterized by the functional deterioration and ultimate loss of neurons. These incurable and debilitating diseases affect millions of people worldwide, and therefore represent a ma
Externí odkaz:
https://doaj.org/article/b5f17450b1694ef2b01e0cb6b0a4ee81