Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Elena W Y, Hsieh"'
Autor:
Ryan M. Baxter, Christine S. Wang, Josselyn E. Garcia-Perez, Daniel S. Kong, Brianne M. Coleman, Valentyna Larchenko, Ronald P. Schuyler, Conner Jackson, Tusharkanti Ghosh, Pratyaydipta Rudra, Debdas Paul, Manfred Claassen, Rosemary Rochford, John C. Cambier, Debashis Ghosh, Jennifer C. Cooper, Mia J. Smith, Elena W. Y. Hsieh
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionMost childhood-onset SLE patients (cSLE) develop lupus nephritis (cLN), but only a small proportion achieve complete response to current therapies. The prognosis of children with LN and end-stage renal disease is particularly dire. Mortal
Externí odkaz:
https://doaj.org/article/a41397a204e54b1f9e4f77656d9bf4c0
Autor:
Mansooreh Ahmadian, Christian Rickert, Angela Minic, Julia Wrobel, Benjamin G Bitler, Fuyong Xing, Michael Angelo, Elena W Y Hsieh, Debashis Ghosh, Kimberly R Jordan
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 9, p e1011432 (2023)
Multiplex imaging is a powerful tool to analyze the structural and functional states of cells in their morphological and pathological contexts. However, hypothesis testing with multiplex imaging data is a challenging task due to the extent and comple
Externí odkaz:
https://doaj.org/article/e7584e9180f24e198429145c9540321c
Autor:
Joseph D, Hernandez, Elena W Y, Hsieh
Publikováno v:
Current Opinion in Pediatrics. 34:580-588
The current review highlights how inborn errors of immunity (IEI) due to IL-2 receptor (IL-2R) subunit defects may result in children presenting with a wide variety of infectious and inflammatory presentations beyond typical X-linked severe combined
Autor:
Ronald P. Schuyler, Conner Jackson, Josselyn E. Garcia-Perez, Ryan M. Baxter, Sidney Ogolla, Rosemary Rochford, Debashis Ghosh, Pratyaydipta Rudra, Elena W. Y. Hsieh
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Cytometry by Time-Of-Flight (CyTOF) uses antibodies conjugated to isotopically pure metals to identify and quantify a large number of cellular features with single-cell resolution. A barcoding approach allows for 20 unique samples to be pooled and pr
Externí odkaz:
https://doaj.org/article/4b7ed76ef1d74cc0b0a1defbed816dc9
Autor:
Josselyn E. Garcia-Perez, Ryan M. Baxter, Daniel S. Kong, Richard Tobin, Martin McCarter, John M. Routes, James Verbsky, Michael B. Jordan, Cullen M. Dutmer, Elena W. Y. Hsieh
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
CTLA-4 is essential for immune tolerance. Heterozygous CTLA4 mutations cause immune dysregulation evident in defective regulatory T cells with low levels of CTLA-4 expression. Biallelic mutations in LRBA also result in immune dysregulation with low l
Externí odkaz:
https://doaj.org/article/c80be548f8aa430a82d406e1f50aadde
Autor:
Victor G. Lui, Tusharkanti Ghosh, Amy Rymaszewski, Shaoying Chen, Ryan M. Baxter, Daniel S. Kong, Debashis Ghosh, John M. Routes, James W. Verbsky, Elena W. Y. Hsieh
Publikováno v:
Journal of Clinical Immunology.
Autor:
Sarah Kulke, Matthew O’Hara, Julie J. Kim-Chang, Cathleen A. Collins, Abigail Silber, Elena W. Y. Hsieh
Publikováno v:
Advances in Therapy
Introduction Characterize the burden of illness in pediatric patients with congen̄ital athymia who were receiving supportive care. Methods This cross-sectional study of adult caregivers of patients with congenital athymia used both a quantitative su
Publikováno v:
Journal of Clinical Immunology
Congenital athymia is an ultra-rare disease characterized by the absence of a functioning thymus. It is associated with several genetic and syndromic disorders including FOXN1 deficiency, 22q11.2 deletion, CHARGE Syndrome (Coloboma, Heart defects, At
Autor:
Ross M. Kedl, Elena W. Y. Hsieh, Thomas E. Morrison, Gabriela Samayoa-Reyes, Siobhan Flaherty, Conner L. Jackson, Rosemary Rochford
Despite the obvious knowledge that infectious particles can be shared through respiration, whether other constituents of the nasal/oral fluids can be passed between hosts has surprisingly never even been postulated, let alone investigated. The circum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcd1c5c3de7f3fbdd2f8bc968d6ca79b
https://doi.org/10.1101/2022.04.28.22274443
https://doi.org/10.1101/2022.04.28.22274443
Autor:
Benjamin S. Frank, Michael DiMaria, Max B. Mitchell, Lori J. Silveira, Jelena Klawitter, Ludmila Khailova, Jesse A. Davidson, Gareth J. Morgan, Mark D. Twite, Elena W Y Hsieh
Publikováno v:
Transl Res
Despite significant morbidity among infants with single ventricle heart disease (SVHD), clinical monitoring is limited by poor understanding of the underlying pathobiology. Proteomics can identify novel biomarkers and important pathways in complex di