Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Elena Viziteu"'
Autor:
Sara Ovejero, Elena Viziteu, Laure Dutrieux, Julie Devin, Yea-Lih Lin, Elina Alaterre, Michel Jourdan, Jihane Basbous, Guilhem Requirand, Nicolas Robert, Hugues de Boussac, Anja Seckinger, Dirk Hose, Laure Vincent, Charles Herbaux, Angelos Constantinou, Philippe Pasero, Jérôme Moreaux
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Multiple myeloma (MM) is a hematologic cancer characterized by accumulation of malignant plasma cells in the bone marrow. To date, no definitive cure exists for MM and resistance to current treatments is one of the major challenges of this disease. T
Externí odkaz:
https://doaj.org/article/8605def9a5a94e54ac65b0f7d255bd7b
Publikováno v:
Journal of visualized experiments : JoVE. (143)
Plasma cells (PCs) secrete large amounts of antibodies and develop from B cells that have been activated. PCs are rare cells located in the bone marrow or mucosa and ensure humoral immunity. Due to their low frequency and location, the study of PCs i
Publikováno v:
Expert Review of Hematology
Expert Review of Hematology, Taylor & Francis, 2016, 9 (4), pp.351-360. ⟨10.1586/17474086.2016.1141673⟩
Expert Review of Hematology, Taylor & Francis, 2016, 9 (4), pp.351-360. ⟨10.1586/17474086.2016.1141673⟩
Acute myeloid leukemia (AML) is a heterogeneous disease at molecular level, in response to therapy and prognosis. The molecular landscape of AML is evolving with new technologies revealing complex panorama of genetic abnormalities where genomic insta
Autor:
Elena Viziteu, Hartmut Goldschmidt, Anja Seckinger, Camille Grandmougin, Bernard Klein, Jérôme Moreaux, Dirk Hose
Publikováno v:
British Journal of Cancer
British Journal of Cancer, Cancer Research UK, 2016, 114 (5), pp.519-523. ⟨10.1038/bjc.2016.20⟩
British Journal of Cancer, Cancer Research UK, 2016, 114 (5), pp.519-523. ⟨10.1038/bjc.2016.20⟩
BACKGROUND: Multiple myeloma (MM) is an incurable clonal plasma cell malignancy. The constitutive expression of HIF-1α in MM suggests that inhibition of HIF-1α-mediated transcription represents an interesting target in MM. METHODS: As p300 is a cru
Autor:
Camille Grandmougin, Anja Seckinger, Laurie Herviou, Laure Vincent, Dirk Hose, Bernard Klein, H. Goldschmidt, Jérôme Moreaux, Philippe Pasero, Julie Devin, N. Robert, Elena Viziteu
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 15:e214-e215
Epigenetics is characterized by a wide range of changes that are reversible and orchestrate gene expression. Recent studies have shown that epigenetic modifications play a role in multiple myeloma (MM) by silencing various cancer-related genes. We in
Autor:
Dirk Hose, Yea-Lih Lin, Angelos Constantinou, Philippe Pasero, Jérôme Moreaux, Elena Viziteu, Laure Vincent, Bernard Klein, Anja Seckinger
Publikováno v:
Blood. 128:4433-4433
Hematological malignancies, including MM, are characterized by genomic instability that is possibly related to underlying defects in DNA repair or genomic stability maintenance. RECQ helicases are at the crossroad between replication, recombination,
Autor:
Julie Devin, Elena Viziteu, Laurie Herviou, Anja Seckinger, Grandmougin Camille, Hartmut Goldschmidt, Laure Vincent, Philippe Pasero, Dirk Hose, Bernard Klein, Jerome Moreaux
Publikováno v:
Blood. 126:1771-1771
Epigenetics is characterized by a wide range of changes that are reversible and orchestrate gene expression. Recent studies have shown that epigenetic modifications play a role in multiple myeloma (MM) by silencing various cancer-related genes. We in
Autor:
Philippe Pasero, Bernard Klein, Jérôme Moreaux, Angelos Constantinou, Jihane Basbous, Camille Grandmougin, Anja Seckinger, Claire Gourzones, Dirk Hose, H. Goldschmidt, Yea-Lih Lin, Elena Viziteu
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 15:e67
are ongoing to inform our efforts of clinically translating CAR T-cell therapy in this entity.
Autor:
Hartmut Goldschmidt, Angelique Bruyer, Angelos Constantinou, Jihane Basbous, Bernard Klein, Jérôme Moreaux, Camille Grandmougin, Elena Viziteu, Dirk Hose
Publikováno v:
Blood. 122:1889-1889
Multiple Myeloma (MM) is a still lethal disease in 2013 characterized by the accumulation in the bone marrow of a clone of malignant plasma cells. Recent studies have shown that epigenetic modifications play a role by silencing various cancer-related
Publikováno v:
Biomarker Research
Biomarker Research, BioMed Central, 2016, 4, pp.3. ⟨10.1186/s40364-016-0057-4⟩
Biomarker Research, 2016, 4, pp.3. ⟨10.1186/s40364-016-0057-4⟩
Biomarker Research, BioMed Central, 2016, 4, pp.3. ⟨10.1186/s40364-016-0057-4⟩
Biomarker Research, 2016, 4, pp.3. ⟨10.1186/s40364-016-0057-4⟩
Background RECQ helicase family members act as guardians of the genome to assure proper DNA metabolism in response to genotoxic stress. Hematological malignancies are characterized by genomic instability that is possibly related to underlying defects