Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Elena Vianini"'
Autor:
Laura Marchetti, Markus Hafner, Christian Gloeckner, Barbara Albertoni, Imke Grüne, Elena Vianini, Michael Famulok
Publikováno v:
Nature protocols
Small molecule inhibitors of proteins are invaluable tools in research and as starting points for drug development. However, their screening can be tedious, as most screening methods have to be tailored to the corresponding drug target. Here, we desc
Publikováno v:
Bioorganic & Medicinal Chemistry. 9:2543-2548
We have applied SELEX (Systematic Evolution of Ligands by EXponential enrichment), a combinatorial method that employs biopolymers for drug discovery, to identify single stranded DNA sequences able to bind l -Tyrosinamide, a simple mimic of Tyrosine,
Autor:
Moltrasio Danilo, Rodolfo Pescador, Elena Vianini, Claudia Sissi, Barbara Gatto, Roberto Porta, Manlio Palumbo, Lorena Lucatello
Publikováno v:
International Journal of Molecular Sciences
Volume 9
Issue 6
Pages 1008-1023
International Journal of Molecular Sciences, Vol 9, Iss 6, Pp 1008-1023 (2008)
Volume 9
Issue 6
Pages 1008-1023
International Journal of Molecular Sciences, Vol 9, Iss 6, Pp 1008-1023 (2008)
Cathepsin G (CatG) is a chymotrypsin-like protease released upon degranulation of neutrophils. In several inflammatory and ischaemic diseases the impaired balance between CatG and its physiological inhibitors leads to tissue destruction and platelet