Evidence that conserved essential genes are enriched for pro-longevity factors

Autor: Naci Oz, Elena Vayndorf, Mitsuhiro Tsuchiya, Samantha McLean, Lesly Turcios-Hernandez, Jason N. Pitt, Ben W. Blue, Michael Muir, Michael G. Kiflezghi, Alexander Tyshkovskiy, Alexander Mendenhall, Matt Kaeberlein, Alaattin Kaya

Publikováno v: GeroScience. 44:1995-2006

At the cellular level, many aspects of aging are conserved across species. This has been demonstrated by numerous studies in simple model organisms like Saccharomyces cerevisiae, Caenorhabdits elegans, and Drosophila melanogaster. Because most geneti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faeabfc061af5d3ce6682c958ec6a109
https://doi.org/10.1007/s11357-022-00604-5

A robotic system for high-throughput automated lifespan and phenotyping analysis in C. elegans

Autor: Richard Nguyen, Jason N. Pitt, Matt Kaeberlein, Emily Chang, Ashley Liang, Renee Ruan, Elena Vayndorf, Judy Z Wu

Publikováno v: Innovation in Aging

A goal of gerontology-related research is to develop therapies to improve the healthy period of life by understanding and targeting the molecular hallmarks of biological aging. Much progress has been made toward understanding the genetic and biochemi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88bc90a6aa0c783f677a85186bcfe067
https://doi.org/10.1093/geroni/igaa057.3270

Cartography of opportunistic pathogens and antibiotic resistance genes in a tertiary hospital environment

Autor: Chng K. R., Li C., Bertrand D., Ng A. H. Q., Kwah J. S., Low H. M., Tong C., Natrajan M., Zhang M. H., Xu L., Ko K. K. K., Ho E. X. P., Av-Shalom T. V., Teo J. W. P., Khor C. C., Danko D., Bezdan D., Afshinnekoo E., Ahsanuddin S., Bhattacharya C., Butler D. J., De Filippis F., Hecht J., Kahles A., Karasikov M., Kyrpides N. C., Leung M. H. Y., Meleshko D., Mustafa H., Mutai B., Neches R. Y., Ng A., Nieto-Caballero M., Nikolayeva O., Nikolayeva T., Png E., Sanchez J. L., Shaaban H., Sierra M. A., Tong X., Young B., Alicea J., Bhattacharyya M., Blekhman R., Castro-Nallar E., Canas A. M., Chatziefthimiou A. D., Crawford R. W., Deng Y., Desnues C., Dias-Neto E., Donnellan D., Dybwad M., Elhaik E., Ercolini D., Frolova A., Graf A. B., Green D. C., Hajirasouliha I., Hernandez M., Iraola G., Jang S., Jones A., Kelly F. J., Knights K., Labaj P. P., Lee P. K. H., Shawn L., Ljungdahl P., Lyons A., Mason-Buck G., McGrath K., Mongodin E. F., Moraes M. O., Nagarajan N., Noushmehr H., Oliveira M., Ossowski S., Osuolale O. O., Ozcan O., Paez-Espino D., Rascovan N., Richard H., Ratsch G., Schriml L. M., Semmler T., Sezerman O. U., Shi L., Song L. H., Suzuki H., Court D. S., Thomas D., Tighe S. W., Udekwu K. I., Ugalde J. A., Valentine B., Vassilev D. I., Vayndorf E., Velavan T. P., Zambrano M. M., Zhu J., Zhu S., Mason C. E., Chen S. L., Ng O. T., Marimuthu K., Ang B.

Publikováno v: Nature Medicine
Nature Medicine, 2020, 26 (6), pp.941-951. ⟨10.1038/s41591-020-0894-4⟩
Nature Medicine, Nature Publishing Group, 2020, 26 (6), pp.941-951. ⟨10.1038/s41591-020-0894-4⟩
Nature Medicine, 26 (6)

Although disinfection is key to infection control, the colonization patterns and resistomes of hospital-environment microbes remain underexplored. We report the first extensive genomic characterization of microbiomes, pathogens and antibiotic resista

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e151ea928c76bf905e5f5def8184306
https://ruj.uj.edu.pl/xmlui/handle/item/281490